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Adaptation is used by biological sensory systems to respond to a wide range of environmental signals, by adapting their response properties to the statistics of the stimulus in order to maximize information transmission. We derive rules of…

Neurons and Cognition · Quantitative Biology 2021-04-14 Daniele Conti , Thierry Mora

Biological sensory systems react to changes in their surroundings. They are characterized by fast response and slow adaptation to varying environmental cues. Insofar as sensory adaptive systems map environmental changes to changes of their…

Statistical Mechanics · Physics 2014-12-15 Pablo Sartori , Léo Granger , Chiu Fan Lee , Jordan M. Horowitz

Biological systems process information under noisy environment. Sensory adaptation model of E. coli is suitable for investigation because of its simplicity. To understand the adaptation processing quantitatively, stochastic thermodynamic…

Molecular Networks · Quantitative Biology 2019-07-16 Keita Ashida , Kotaro Oka

Sensory adaptation enables organisms to adjust their perception in a changing environment. A paradigm is bacterial chemotaxis, where the output activity of chemoreceptors is adapted to different baseline concentrations via receptor…

Cell Behavior · Quantitative Biology 2024-01-23 Vansh Kharbanda , Benedikt Sabass

Adaptive physical and biological systems continually process fluctuating information from their environments. When the environment is nonstationary, inference itself becomes a nonequilibrium process with thermodynamic cost. We analyse a…

Statistical Mechanics · Physics 2026-03-23 Aditya Gupta

Biological systems display impressive capabilities in effectively responding to environmental signals in real time. There is increasing evidence that organisms may indeed be employing near optimal Bayesian calculations in their…

Neurons and Cognition · Quantitative Biology 2010-02-12 Steve Yaeli , Ron Meir

Living systems need to be highly responsive, and also to keep fluctuations low. These goals are incompatible in equilibrium systems due to the Fluctuation Dissipation Theorem (FDT). Here, we show that biological sensory systems, driven far…

Biological Physics · Physics 2015-09-16 Pablo Sartori , Yuhai Tu

How do organisms recognize their environment by acquiring knowledge about the world, and what actions do they take based on this knowledge? This article examines hypotheses about organisms' adaptation to the environment from machine…

Neurons and Cognition · Quantitative Biology 2019-03-01 Hideaki Shimazaki

The ability to monitor nutrient and other environmental conditions with high sensitivity is crucial for cell growth and survival. Sensory adaptation allows a cell to recover its sensitivity after a transient response to a shift in the…

Subcellular Processes · Quantitative Biology 2016-01-07 Shou-Wen Wang , Yueheng Lan , Lei-Han Tang

The interplay between information, dissipation, and control is reshaping our understanding of thermodynamics in feedback-regulated systems. We develop the informational Onsager-Machlup principle, a generalized variational framework that…

Soft Condensed Matter · Physics 2026-04-30 Kento Yasuda , Kenta Ishimoto , Shigeyuki Komura

We derive a class of macroscopic differential equations that describe collective adaptation, starting from a discrete-time stochastic microscopic model. The behavior of each agent is a dynamic balance between adaptation that locally…

Adaptation and Self-Organizing Systems · Physics 2024-05-15 Yuzuru Sato , Eizo Akiyama , James P. Crutchfield

Agents acting in the natural world aim at selecting appropriate actions based on noisy and partial sensory observations. Many behaviors leading to decision mak- ing and action selection in a closed loop setting are naturally phrased within…

Machine Learning · Statistics 2014-06-30 Alex Susemihl , Ron Meir , Manfred Opper

Adaptive systems -- such as a biological organism gaining survival advantage, an autonomous robot executing a functional task, or a motor protein transporting intracellular nutrients -- must model the regularities and stochasticity in their…

Statistical Mechanics · Physics 2021-04-13 A. B. Boyd , J. P. Crutchfield , M. Gu

Starting at the mesoscopic level with a general formulation of stochastic thermodynamics in terms of Markov jump processes, we identify the scaling conditions that ensure the emergence of a (typically nonlinear) deterministic dynamics and…

Statistical Mechanics · Physics 2025-05-26 Gianmaria Falasco , Massimiliano Esposito

The signaling apparatus mediating bacterial chemotaxis can adapt to a wide range of persistent external stimuli. In many cases, the bacterial activity returns to its pre-stimulus level exactly and this "perfect adaptability" is robust…

Biological Physics · Physics 2017-10-16 Bernardo A. Mello , Yuhai Tu

Adaptation of the chemotaxis sensory pathway of the bacterium Escherichia coli is integral for detecting chemicals over a wide range of background concentrations, ultimately allowing cells to swim towards sources of attractant and away from…

Cell Behavior · Quantitative Biology 2015-05-18 Diana Clausznitzer , Olga Oleksiuk , Linda Lovdok , Victor Sourjik , Robert G. Endres

Recent research in robot exploration and mapping has focused on sampling environmental hotspot fields. This exploration task is formalized by Low, Dolan, and Khosla (2008) in a sequential decision-theoretic planning under uncertainty…

Machine Learning · Computer Science 2013-05-28 Kian Hsiang Low , John M. Dolan , Pradeep Khosla

Stochastic thermodynamics has largely succeeded in characterizing both equilibrium and far-from-equilibrium phenomena. Yet many opportunities remain for application to mesoscopic complex systems -- especially biological ones -- whose…

Statistical Mechanics · Physics 2022-11-08 Mikhael T. Semaan , James P. Crutchfield

The linear response to temperature changes is derived for systems with overdamped stochastic dynamics. Holding both in transient and steady state conditions, the results allow to compute nonequilibrium thermal susceptibilities from…

Statistical Mechanics · Physics 2016-04-11 Gianmaria Falasco , Marco Baiesi

Living cells often need to measure chemical concentrations that vary in time. To this end, they deploy many resources, e.g. receptors, downstream signaling molecules, time and energy. Here, we present a theory for the optimal design of a…

Molecular Networks · Quantitative Biology 2019-02-26 G. Malaguti , P. R. ten Wolde
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