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Accurate prostate cancer diagnosis remains challenging. Even when using MRI, radiologists exhibit low specificity and significant inter-observer variability, leading to potential delays or inaccuracies in identifying clinically significant…

Background: Artificial intelligence (AI) assisted lung nodule detection systems are increasingly deployed in clinical settings without site-specific validation. Performance reported under benchmark conditions may not reflect real-world…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Daniel Soliman

Revealing novel insights from the relationship between molecular measurements and pathology remains a very impactful application of machine learning in biomedicine. Data in this domain typically contain only a few observations but thousands…

Machine Learning · Computer Science 2026-03-31 Christopher Kolberg , Jules Kreuer , Jonas Huurdeman , Sofiane Ouaari , Katharina Eggensperger , Nico Pfeifer

This study presents a lightweight pipeline for skin lesion detection, addressing the challenges posed by imbalanced class distribution and subtle or atypical appearances of some lesions. The pipeline is built around a lightweight model that…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Mingzhe Hu , Xiaofeng Yang

Recent Tabular Foundation Models (TFMs) have demonstrated state-of-the-art predictive performance, often surpassing Gradient-Boosted Decision Trees (GBDTs). However, the trustworthiness of these models, particularly their uncertainty…

Machine Learning · Computer Science 2026-05-28 José Lucas De Melo Costa , Fabrice Popineau , Arpad Rimmel , Bich-Liên Doan

Objective: Organ deformation models have the potential to improve delivery and reduce toxicity of radiotherapy, but existing data-driven motion models are based on either patient-specific or population data. We propose to combine population…

The emergence of multi-modal deep learning models has made significant impacts on clinical applications in the last decade. However, the majority of models are limited to single-tasking, without considering disease diagnosis is indeed a…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Lijian Xu , Ziyu Ni , Xinglong Liu , Xiaosong Wang , Hongsheng Li , Shaoting Zhang

Pathology foundation models (PFMs) have advanced rapidly in recent years and support training classifiers for a range of histopathology tasks. However, their robustness across hospitals remains limited: performance often degrades when…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Ben Vardi , Dana Schonberger , Yuval Friedmann , Zohar Yakhini , Iris Barshack , Alexander Loebel , Ariel Shamir

Mitotic figures are classified into typical and atypical variants, with atypical counts correlating strongly with tumor aggressiveness. Accurate differentiation is therefore essential for patient prognostication and resource allocation, yet…

Image and Video Processing · Electrical Eng. & Systems 2025-09-19 Mieko Ochi , Bae Yuan

The ability to reason about and predict the outcome of contacts is paramount to the successful execution of many robot tasks. Analytical rigid-body contact models are used extensively in planning and control due to their computational…

Robotics · Computer Science 2017-11-06 Nima Fazeli , Samuel Zapolsky , Evan Drumwright , Alberto Rodriguez

Medical foundation models show promise to learn broadly generalizable features from large, diverse datasets. This could be the base for reliable cross-modality generalization and rapid adaptation to new, task-specific goals, with only a few…

Accurate disease trajectory prediction is critical for early intervention, resource allocation, and improving long-term outcomes. While electronic health records (EHRs) provide a rich longitudinal view of patient health in clinical…

Machine Learning · Computer Science 2026-05-15 Yunying Zhu , Andrew R Weckstein , Kueiyu Joshua Lin , Jie Yang

Foundation models (FMs) have demonstrated strong performance across diverse pathology tasks. While there are similarities in the pre-training objectives of FMs, there is still limited understanding of their complementarity, redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Brennan Flannery , Thomas DeSilvio , Jane Nguyen , Satish E. Viswanath

The shortage of nephrologists and the growing public health concern over renal failure have spurred the demand for AI systems capable of autonomously detecting kidney abnormalities. Renal failure, marked by a gradual decline in kidney…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Tahmim Hossain , Faisal Sayed , Solehin Islam

Medical image segmentation is crucial for disease diagnosis and treatment planning, yet developing robust segmentation models often requires substantial computational resources and large datasets. Existing research shows that pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Paul Zaha , Lars Böcking , Simeon Allmendinger , Leopold Müller , Niklas Kühl

Machine learning models are typically deployed in a test setting that differs from the training setting, potentially leading to decreased model performance because of domain shift. If we could estimate the performance that a pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2022-07-21 Zeju Li , Konstantinos Kamnitsas , Mobarakol Islam , Chen Chen , Ben Glocker

Federated learning enables collaborative model training across medical institutions without sharing raw data, but its performance is often limited by domain heterogeneity across clients. Existing approaches to address this challenge fall…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Chamani Shiranthika , Parvaneh Saeedi

ECG foundation models are increasingly popular due to their adaptability across various tasks. However, their clinical applicability is often limited by performance gaps compared to task-specific models, even after pre-training on large ECG…

Machine Learning · Computer Science 2026-01-30 Ya Zhou , Yujie Yang , Xiaohan Fan , Wei Zhao

State-of-the-art vessel segmentation methods typically require large-scale annotated datasets and suffer from severe performance degradation under domain shifts. In clinical practice, however, acquiring extensive annotations for every new…

Image and Video Processing · Electrical Eng. & Systems 2026-03-02 Kirato Yoshihara , Yohei Sugawara , Yuta Tokuoka , Lihang Hong

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…