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\textbf{Background:} Regulatory frameworks for AI in healthcare, including the EU AI Act and FDA guidance on AI/ML-based medical devices, require clinical decision support to demonstrate not only accuracy but auditability. Existing formal…

Artificial Intelligence · Computer Science 2026-04-24 Michael Bouzinier , Sergey Trifonov , Michael Chumack , Eugenia Lvova , Dmitry Etin

Syllogistic reasoning is crucial for Natural Language Inference (NLI). This capability is particularly significant in specialized domains such as biomedicine, where it can support automatic evidence interpretation and scientific discovery.…

Computation and Language · Computer Science 2025-02-11 Magdalena Wysocka , Danilo Carvalho , Oskar Wysocki , Marco Valentino , Andre Freitas

Large language models (LLMs) exhibit remarkable performance across various NLP tasks. However, they often generate incorrect or hallucinated information, which hinders their practical applicability in real-world scenarios. Human feedback…

Computation and Language · Computer Science 2023-05-24 Wenhao Yu , Zhihan Zhang , Zhenwen Liang , Meng Jiang , Ashish Sabharwal

The surging amount of biomedical literature & digital clinical records presents a growing need for text mining techniques that can not only identify but also semantically relate entities in unstructured data. In this paper we propose a text…

Computation and Language · Computer Science 2021-12-28 Hasham Ul Haq , Veysel Kocaman , David Talby

Large Language Models (LLMs) offer a promising avenue for scientific discovery, yet their application to symbolic regression is often constrained by inefficient search strategies and coarse feedback signals. Current methods typically guide…

Machine Learning · Computer Science 2026-05-29 Evgeny S. Saveliev , Samuel Holt , Nabeel Seedat , David L. Bentley , Jim Weatherall , Mihaela van der Schaar

Prompt engineering significantly influences the reliability and clinical utility of Large Language Models (LLMs) in medical applications. Current optimization approaches inadequately address domain-specific medical knowledge and safety…

Computation and Language · Computer Science 2025-08-26 Yinda Chen , Yangfan He , Jing Yang , Dapeng Zhang , Zhenlong Yuan , Muhammad Attique Khan , Jamel Baili , Por Lip Yee

Retrieval-augmented generation (RAG) faces challenges related to factual correctness, source attribution, and response completeness. The LiveRAG Challenge hosted at SIGIR'25 aims to advance RAG research using a fixed corpus and a shared,…

Information Retrieval · Computer Science 2025-06-30 Weronika Łajewska , Ivica Kostric , Gabriel Iturra-Bocaz , Mariam Arustashvili , Krisztian Balog

Speech monologues recorded in naturalistic settings provide opportunities to characterize mental illness phenomenology and detect symptom exacerbation. Large language models (LLMs) offer new possibilities for automating this process, as…

Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a…

Previous work has demonstrated that AI methods for analysing scientific literature benefit significantly from annotating sentences in papers according to their rhetorical roles, such as research gaps, results, limitations, extensions of…

Computation and Language · Computer Science 2026-02-11 Francisco Bolaños , Angelo Salatino , Francesco Osborne , Enrico Motta

High throughput extraction and structured labeling of data from academic articles is critical to enable downstream machine learning applications and secondary analyses. We have embedded multimodal data curation into the academic publishing…

Computation and Language · Computer Science 2024-09-26 Jorge Abreu-Vicente , Hannah Sonntag , Thomas Eidens , Cassie S. Mitchell , Thomas Lemberger

Retrieval systems are increasingly used in biomedical and clinical natural language processing applications, yet practical guidance for researchers building such systems is limited. In this work, we provide such guidance through an…

Information Retrieval · Computer Science 2026-04-24 Hayk Stepanyan , Matthew McDermott

Large Language Models (LLMs) are transforming information extraction from academic literature, offering new possibilities for knowledge management. This study presents an LLM-based system designed to extract detailed information about…

Information Retrieval · Computer Science 2025-05-29 Jiseung Yoo , Curran Mahowald , Meiyu Li , Wei Ai

There are a few challenges related to the task of biomedical named entity recognition, which are: the existing methods consider a fewer number of biomedical entities (e.g., disease, symptom, proteins, genes); and these methods do not…

Computation and Language · Computer Science 2022-07-05 Shaina Raza , Brian Schwartz

In clinical research and clinical decision-making, it is important to know if a study changes or only supports the current standards of care for specific disease management. We define such a change as transformative and a support as…

Computation and Language · Computer Science 2021-12-28 Xuanyu Shi , Jian Du

Clinical trial eligibility matching is a critical yet often labor-intensive and error-prone step in medical research, as it ensures that participants meet precise criteria for safe and reliable study outcomes. Recent advances in Natural…

Machine Learning · Computer Science 2025-03-04 Muhammad Talha Sharif , Abdul Rehman

Large language models (LLMs) like ChatGPT can generate and revise text with human-level performance. These models come with clear limitations: they can produce inaccurate information, reinforce existing biases, and be easily misused. Yet,…

Computation and Language · Computer Science 2025-07-04 Dmitry Kobak , Rita González-Márquez , Emőke-Ágnes Horvát , Jan Lause

The rapid rise in AI conference submissions has driven increasing exploration of large language models (LLMs) for peer review support. However, LLM-based reviewers often generate superficial, formulaic comments lacking substantive,…

Computation and Language · Computer Science 2026-04-17 Zhuofeng Li , Yi Lu , Dongfu Jiang , Haoxiang Zhang , Yuyang Bai , Chuan Li , Yu Wang , Shuiwang Ji , Jianwen Xie , Yu Zhang

High-performing medical Large Language Models (LLMs) typically require extensive fine-tuning with substantial computational resources, limiting accessibility for resource-constrained healthcare institutions. This study introduces a…

Computation and Language · Computer Science 2025-10-17 Ziad Elshaer , Essam A. Rashed

Jailbreaking in Large Language Models (LLMs) threatens their safe use in sensitive domains like education by allowing users to bypass ethical safeguards. This study focuses on detecting jailbreaks in 2-Sigma, a clinical education platform…