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Related papers: Identifying Evidence-Based Nudges in Biomedical Li…

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Manually curated biomedical repositories -- spanning bioactivity, genomics, and chemistry -- are expensive to maintain, lag behind primary literature, and discard experimental context, obscuring nuances needed to assess data correctness and…

Large Language Models (LLMs) demonstrate remarkable versatility in various NLP tasks but encounter distinct challenges in biomedical due to the complexities of language and data scarcity. This paper investigates LLMs application in the…

Computation and Language · Computer Science 2024-07-12 Masoud Monajatipoor , Jiaxin Yang , Joel Stremmel , Melika Emami , Fazlolah Mohaghegh , Mozhdeh Rouhsedaghat , Kai-Wei Chang

Large language models (LLMs) show promise for extracting clinically meaningful information from unstructured health records, yet their translation into real-world settings is constrained by the lack of scalable and trustworthy validation…

We introduce Biomed-Enriched, a biomedical text dataset constructed from PubMed via a two-stage annotation process. In the first stage, a large language model annotates 400K paragraphs from PubMed scientific articles, assigning scores for…

Computation and Language · Computer Science 2025-06-26 Rian Touchent , Nathan Godey , Eric de la Clergerie

A significant and growing number of published scientific articles is found to involve fraudulent practices, posing a serious threat to the credibility and safety of research in fields such as medicine. We propose Pub-Guard-LLM, the first…

Computation and Language · Computer Science 2025-08-22 Lihu Chen , Shuojie Fu , Gabriel Freedman , Cemre Zor , Guy Martin , James Kinross , Uddhav Vaghela , Ovidiu Serban , Francesca Toni

We present MedNuggetizer, https://mednugget-ai.de/; access is available upon request.}, a tool for query-driven extraction and clustering of information nuggets from medical documents to support clinicians in exploring underlying medical…

The fundamental process of evidence extraction and synthesis in evidence-based medicine involves extracting PICO (Population, Intervention, Comparison, and Outcome) elements from biomedical literature. However, Outcomes, being the most…

Computation and Language · Computer Science 2025-06-09 Yiliang Zhou , Abigail M. Newbury , Gongbo Zhang , Betina Ross Idnay , Hao Liu , Chunhua Weng , Yifan Peng

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Academic literature reviews have traditionally relied on techniques such as keyword searches and accumulation of relevant back-references, using databases like Google Scholar or IEEEXplore. However, both the precision and accuracy of these…

Human-Computer Interaction · Computer Science 2024-08-27 Hongye An , Arpit Narechania , Emily Wall , Kai Xu

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

Scientific discovery pipelines typically involve complex, rigid, and time-consuming processes, from data preparation to analyzing and interpreting findings. Recent advances in AI have the potential to transform such pipelines in a way that…

Machine Learning · Computer Science 2026-02-20 Paimon Goulart , Jordan Steinhauser , Dawon Ahn , Kylene Shuler , Edward Korzus , Jia Chen , Evangelos E. Papalexakis

We study the task of automatically finding evidence relevant to hypotheses in biomedical papers. Finding relevant evidence is an important step when researchers investigate scientific hypotheses. We introduce EvidenceBench to measure models…

Frontier large language models generate clinically accurate outputs, but their citations are often fabricated. We term this the Provenance Gap. We tested five frontier LLMs across 36 clinician-validated scenarios for three rare…

Large language models (LLMs) have shown remarkable capabilities in Natural Language Processing (NLP), especially in domains where labeled data is scarce or expensive, such as clinical domain. However, to unlock the clinical knowledge hidden…

Computation and Language · Computer Science 2023-09-18 Sonish Sivarajkumar , Mark Kelley , Alyssa Samolyk-Mazzanti , Shyam Visweswaran , Yanshan Wang

The growing use of large language models (LLMs) for biomedical question answering raises concerns about the accuracy and evidentiary support of their responses. To address this, we present Answered with Evidence, a framework for evaluating…

Machine Learning · Computer Science 2025-07-08 Julian D Baldwin , Christina Dinh , Arjun Mukerji , Neil Sanghavi , Saurabh Gombar

Over the past decade, extensive research efforts have been dedicated to the extraction of information from textual process descriptions. Despite the remarkable progress witnessed in natural language processing (NLP), information extraction…

Computation and Language · Computer Science 2024-07-29 Julian Neuberger , Lars Ackermann , Han van der Aa , Stefan Jablonski

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

The extraction of structured knowledge from scientific literature remains a major bottleneck in nutraceutical research, particularly when identifying microbial strains involved in compound biosynthesis. This study presents a domain-adapted…

Quantitative Methods · Quantitative Biology 2025-12-30 Xinyang Sun , Nipon Sarmah , Miao Guo

Large language models (LLMs) are increasingly recognized as valuable tools across the medical environment, supporting clinical, research, and administrative workflows. However, strict privacy and network security regulations in hospital…

Computation and Language · Computer Science 2026-01-09 Seokhwan Ko , Donghyeon Lee , Jaewoo Chun , Hyungsoo Han , Junghwan Cho
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