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Randomized experiments have become a cornerstone of evidence-based decision-making in contexts ranging from online platforms to public health. However, in experimental settings with network interference, a unit's treatment can influence…

Machine Learning · Computer Science 2025-10-22 Sadegh Shirani , Yuwei Luo , William Overman , Ruoxuan Xiong , Mohsen Bayati

Background: Small interfering RNA (siRNA) is a promising therapeutic agent due to its ability to silence disease-related genes via RNA interference. While traditional machine learning and early deep learning methods have made progress in…

Biomolecules · Quantitative Biology 2025-03-07 Wangdan Liao , Weidong Wang

The correct interpretation of convolutional models is a hard problem for time series data. While saliency methods promise visual validation of predictions for image and language processing, they fall short when applied to time series. These…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Christoffer Loeffler , Wei-Cheng Lai , Bjoern Eskofier , Dario Zanca , Lukas Schmidt , Christopher Mutschler

Interpretable machine learning and explainable artificial intelligence have become essential in many applications. The trade-off between interpretability and model performance is the traitor to developing intrinsic and model-agnostic…

Machine Learning · Computer Science 2023-09-06 Chiara Balestra , Bin Li , Emmanuel Müller

Deep neural networks have shown their profound impact on achieving human level performance in visual saliency prediction. However, it is still unclear how they learn the task and what it means in terms of understanding human visual system.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Sai Phani Kumar Malladi , Jayanta Mukhopadhyay , Chaker Larabi , Santanu Chaudhury

Saliency methods are a popular class of feature attribution explanation methods that aim to capture a model's predictive reasoning by identifying "important" pixels in an input image. However, the development and adoption of these methods…

Machine Learning · Computer Science 2022-06-20 Joon Sik Kim , Gregory Plumb , Ameet Talwalkar

In recent years, Artificial Intelligence has become a powerful partner for complex tasks such as data analysis, prediction, and problem-solving, yet its lack of transparency raises concerns about its reliability. In sensitive domains such…

Machine Learning · Computer Science 2026-03-10 Jesús Sánchez Ochoa , Enrique Tomás Martínez Beltrán , Alberto Huertas Celdrán

Traditional compartmental models, including SIR, SEIR, and SIRS frameworks, remain the analytical standard for epidemic forecasting. However, real-world data validation consistently reveals significant predictive failures, such as peak…

Physics and Society · Physics 2026-02-02 Jose de Jesus Bernal-Alvarado , David Delepine

Explainability in time series forecasting is essential for improving model transparency and supporting informed decision-making. In this work, we present CrossScaleNet, an innovative architecture that combines a patch-based cross-attention…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Ibrahim Delibasoglu , Fredrik Heintz

Interpretability is a critical factor in applying complex deep learning models to advance the understanding of brain disorders in neuroimaging studies. To interpret the decision process of a trained classifier, existing techniques typically…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Zixuan Liu , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao

LLM confidence signals are used for abstention, routing, and safety-critical decisions. No standard practice exists for checking whether a confidence signal carries item-level information before building on it. We transfer the validity…

Computation and Language · Computer Science 2026-04-21 Jon-Paul Cacioli

Feed-forward only convolutional neural networks (CNNs) may ignore intrinsic relationships and potential benefits of feedback connections in vision tasks such as saliency detection, despite their significant representation capabilities. In…

Computer Vision and Pattern Recognition · Computer Science 2022-01-12 Guanqun Ding , Nevrez Imamoglu , Ali Caglayan , Masahiro Murakawa , Ryosuke Nakamura

Empirical investigations into unintended model behavior often show that the algorithm is predicting another outcome than what was intended. These exposes highlight the need to identify when algorithms predict unintended quantities - ideally…

Methodology · Statistics 2026-01-27 Amanda Coston

The fundamental challenge of drawing causal inference is that counterfactual outcomes are not fully observed for any unit. Furthermore, in observational studies, treatment assignment is likely to be confounded. Many statistical methods have…

Methodology · Statistics 2022-08-01 Harsh Parikh , Carlos Varjao , Louise Xu , Eric Tchetgen Tchetgen

As large-scale training regimes have gained popularity, the use of pretrained models for downstream tasks has become common practice in machine learning. While pretraining has been shown to enhance the performance of models in practice, the…

Machine Learning · Computer Science 2023-10-10 Laura Fee Nern , Harsh Raj , Maurice Georgi , Yash Sharma

Saliency maps have shown to be both useful and misleading for explaining model predictions especially in the context of images. In this paper, we perform sanity checks for text modality and show that the conclusions made for image do not…

Machine Learning · Computer Science 2021-06-15 Narine Kokhlikyan , Vivek Miglani , Bilal Alsallakh , Miguel Martin , Orion Reblitz-Richardson

Robust machine learning for regulatory genomics is studied under biologically and technically induced distribution shifts. Deep convolutional and attention based models achieve strong in distribution performance on DNA regulatory sequence…

Genomics · Quantitative Biology 2026-02-20 Yiyao Yang

Tables provide valuable knowledge that can be used to verify textual statements. While a number of works have considered table-based fact verification, direct alignments of tabular data with tokens in textual statements are rarely…

Computation and Language · Computer Science 2021-09-10 Fei Wang , Kexuan Sun , Jay Pujara , Pedro Szekely , Muhao Chen

Saliency is the perceptual capacity of our visual system to focus our attention (i.e. gaze) on relevant objects. Neural networks for saliency estimation require ground truth saliency maps for training which are usually achieved via…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 Carola Figueroa-Flores , David Berga , Joost van der Weijer , Bogdan Raducanu

Traditional saliency map methods, popularized in computer vision, highlight individual points (pixels) of the input that contribute the most to the model's output. However, in time series, they offer limited insights, as semantically…

Machine Learning · Computer Science 2026-05-08 Christodoulos Kechris , Jonathan Dan , David Atienza