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The 12-lead electrocardiogram (ECG) is a commonly used tool for detecting cardiac abnormalities such as atrial fibrillation, blocks, and irregular complexes. For the PhysioNet/CinC 2020 Challenge, we built an algorithm using gradient…

Signal Processing · Electrical Eng. & Systems 2020-10-27 Alexander William Wong , Weijie Sun , Sunil Vasu Kalmady , Padma Kaul , Abram Hindle

Electrocardiogram (ECG) interpretation is essential for diagnosing a wide range of cardiac abnormalities. While deep learning has shown strong potential for automating ECG classification, many existing models rely on large, computationally…

Numerous studies are aimed at diagnosing heart diseases based on 12-lead electrocardiographic (ECG) records using deep learning methods. These studies usually use specific datasets that differ in size and parameters, such as patient…

Signal Processing · Electrical Eng. & Systems 2023-05-31 Aram Avetisyan , Shahane Tigranyan , Ariana Asatryan , Olga Mashkova , Sergey Skorik , Vladislav Ananev , Yury Markin

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

We are concerned with the challenge of reliably classifying and assessing intracranial aneurysms using deep learning without compromising clinical transparency. While traditional black-box models achieve high predictive accuracy, their lack…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Toqa Khaled , Ahmad Al-Kabbany

Interpreting and communicating electrocardiogram (ECG) findings are crucial yet challenging tasks in cardiovascular diagnosis, traditionally requiring significant expertise and precise clinical communication. This paper introduces…

Signal Processing · Electrical Eng. & Systems 2025-10-30 Koustav Mallick , Neel Singh , Mohammedreza Hajiarbabi

This paper reviews recent studies in understanding neural-network representations and learning neural networks with interpretable/disentangled middle-layer representations. Although deep neural networks have exhibited superior performance…

Computer Vision and Pattern Recognition · Computer Science 2018-02-08 Quanshi Zhang , Song-Chun Zhu

Electrocardiogram signals are omnipresent in medicine. A vital aspect in the analysis of this data is the identification and classification of heart beat types which is often done through automated algorithms. Advancements in neural…

Machine Learning · Computer Science 2019-11-13 Tom Van Steenkiste , Dirk Deschrijver , Tom Dhaene

Echocardiography is essential to modern cardiology. However, human interpretation limits high throughput analysis, limiting echocardiography from reaching its full clinical and research potential for precision medicine. Deep learning is a…

Computer Vision and Pattern Recognition · Computer Science 2017-06-28 Ali Madani , Ramy Arnaout , Mohammad Mofrad , Rima Arnaout

One significant challenge of exploiting Graph neural networks (GNNs) in real-life scenarios is that they are always treated as black boxes, therefore leading to the requirement of interpretability. To address this, model-level…

Machine Learning · Computer Science 2025-09-22 Xiao Yue , Guangzhi Qu , Lige Gan

The rapid advancements in Artificial Intelligence, specifically Machine Learning (ML) and Deep Learning (DL), have opened new prospects in medical sciences for improved diagnosis, prognosis, and treatment of severe health conditions. This…

Machine Learning · Computer Science 2024-12-11 Atit Pokharel , Shashank Dahal , Pratik Sapkota , Bhupendra Bimal Chhetri

With the development of deep learning-based methods, automated classification of electrocardiograms (ECGs) has recently gained much attention. Although the effectiveness of deep neural networks has been encouraging, the lack of information…

Signal Processing · Electrical Eng. & Systems 2022-03-02 Wenrui Zhang , Xinxin Di , Guodong Wei , Shijia Geng , Zhaoji Fu , Shenda Hong

Deep neural networks have achieved remarkable success in various challenging tasks. However, the black-box nature of such networks is not acceptable to critical applications, such as healthcare. In particular, the existence of adversarial…

Machine Learning · Computer Science 2019-09-12 Shaeke Salman , Seyedeh Neelufar Payrovnaziri , Xiuwen Liu , Pablo Rengifo-Moreno , Zhe He

Cardiovascular diseases (CVDs) are the leading cause of global mortality, necessitating accessible and accurate diagnostic tools. While cardiac magnetic resonance imaging (CMR) provides gold-standard insights into cardiac structure and…

Interpretability is highly desired for deep neural network-based classifiers, especially when addressing high-stake decisions in medical imaging. Commonly used post-hoc interpretability methods have the limitation that they can produce…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Sourya Sengupta , Mark A. Anastasio

A key technology enabling the success of catheter ablation treatment for atrial tachycardia is activation mapping, which relies on manual local activation time (LAT) annotation of all acquired intracardiac electrogram (EGM) signals. This is…

Signal Processing · Electrical Eng. & Systems 2022-06-16 Zerui Chen , Sonia Xhyn Teo , Andrie Ochtman , Shier Nee Saw , Nicholas Cheng , Eric Tien Siang Lim , Murphy Lyu , Hwee Kuan Lee

The electrocardiogram (ECG) is an essential non-invasive diagnostic tool for assessing cardiac conditions. Existing automatic interpretation methods suffer from limited generalizability, focusing on a narrow range of cardiac conditions, and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Ruoqi Liu , Yuelin Bai , Xiang Yue , Ping Zhang

Cardiovascular disease is a large worldwide healthcare issue; symptoms often present suddenly with minimal warning. The electrocardiogram (ECG) is a fast, simple and reliable method of evaluating the health of the heart, by measuring…

Signal Processing · Electrical Eng. & Systems 2022-01-15 Yola Jones , Fani Deligianni , Jeff Dalton

Background: Electrocardiogram (ECG) analysis has emerged as a promising tool for detecting physiological changes linked to non-cardiac disorders. Given the close connection between cardiovascular and neurocognitive health, ECG abnormalities…

Signal Processing · Electrical Eng. & Systems 2025-11-20 Juan Miguel Lopez Alcaraz , Ebenezer Oloyede , David Taylor , Wilhelm Haverkamp , Nils Strodthoff

We present a model for predicting electrocardiogram (ECG) abnormalities in short-duration 12-lead ECG signals which outperformed medical doctors on the 4th year of their cardiology residency. Such exams can provide a full evaluation of…