English
Related papers

Related papers: scBench: Evaluating AI Agents on Single-Cell RNA-s…

200 papers

The rapid deployment of AI agents in commercial settings has outpaced the development of evaluation methodologies that reflect production realities. Existing benchmarks measure agent capabilities through retrospectively curated tasks with…

Evaluating AI agents in finance faces two key challenges: static benchmarks require costly expert annotation yet miss the dynamic decision-making central to real-world trading, while LLM-based judges introduce uncontrolled variance on…

Artificial Intelligence · Computer Science 2026-03-03 Xiaochuang Yuan , Hui Xu , Silvia Xu , Cui Zou , Jing Xiong

Recent advances in medical large language models (LLMs), multimodal models, and agents demand evaluation frameworks that reflect real clinical workflows and safety constraints. We present MedBench v4, a nationwide, cloud-based benchmarking…

Agent skills, structured procedural knowledge packages injected at inference time, are increasingly used to augment LLM agents on software engineering tasks. However, their real utility in end-to-end development settings remains unclear. We…

Software Engineering · Computer Science 2026-03-17 Tingxu Han , Yi Zhang , Wei Song , Chunrong Fang , Zhenyu Chen , Youcheng Sun , Lijie Hu

As LLM agents are increasingly built around reusable skills, a central challenge is no longer only whether agents can use provided skills, but whether they can generate correct, reusable, and executable skills from repositories and…

Artificial Intelligence · Computer Science 2026-05-19 Yifan Zhou , Zhentao Zhang , Ziming Cheng , Shuo Zhang , Qizhen Lan , Zhangquan Chen , Zhi Yang , QianyuXu , Ronghao Chen , Huacan Wang , Sen Hu

Reusable skills are becoming a common interface for extending large language model agents, packaging procedural guidance with access to files, tools, memory, and execution environments. However, this modularity introduces attack surfaces…

Cryptography and Security · Computer Science 2026-05-28 Chang Jin , An Wang , Zeming Wei , Kai Wang , Biaojie Zeng , Qiaosheng Zhang , Chao Yang , Jingjing Qu , Xia Hu , Xingcheng Xu

Performance bugs are inefficiencies in software that waste computational resources without causing functional failures, making them particularly challenging to detect and fix. While recent advances in Software Engineering agents have shown…

Software Engineering · Computer Science 2025-12-04 Spandan Garg , Roshanak Zilouchian Moghaddam , Neel Sundaresan

Goal changes are a defining feature of real world multi-turn interactions, yet current agent benchmarks primarily evaluate static objectives or one-shot tool use. We introduce AgentChangeBench, a benchmark explicitly designed to measure how…

Artificial Intelligence · Computer Science 2025-10-22 Manik Rana , Calissa Man , Anotida Expected Msiiwa , Jeffrey Paine , Kevin Zhu , Sunishchal Dev , Vasu Sharma , Ahan M R

Frontier AI systems are increasingly capable and deployed in high-stakes multi-agent environments. However, existing AI safety benchmarks largely evaluate single agents, leaving multi-agent risks such as coordination failure and conflict…

Artificial Intelligence · Computer Science 2026-05-25 Pepijn Cobben , Xuanqiang Angelo Huang , Thao Amelia Pham , Isabel Dahlgren , Terry Jingchen Zhang , Zhijing Jin

AI agents are an exciting new research direction, and agent development is driven by benchmarks. Our analysis of current agent benchmarks and evaluation practices reveals several shortcomings that hinder their usefulness in real-world…

Machine Learning · Computer Science 2024-07-02 Sayash Kapoor , Benedikt Stroebl , Zachary S. Siegel , Nitya Nadgir , Arvind Narayanan

The field of single-cell biology is growing rapidly and is generating large amounts of data from a variety of species, disease conditions, tissues, and organs. Coordinated efforts such as CZI CELLxGENE, HuBMAP, Broad Institute Single Cell…

LLM agents now perform strongly in software engineering, deep research, GUI automation, and various other applications, while recent agent scaffolds and models are increasingly integrating these capabilities into unified systems. Yet, most…

Modern coding scaffolds turn LLMs into capable software agents, but their ability to follow scaffold-specified instructions remains under-examined, especially when constraints are heterogeneous and persist across interactions. To fill this…

Scientific evidence often spans instruments, databases, and disciplines, so no single source records the full phenomenon. This makes it difficult to determine when coordinated AI agents add value over simpler scientific workflows. We…

Artificial Intelligence · Computer Science 2026-05-22 Fiona Y. Wong , Markus J. Buehler

Scientific knowledge bases accelerate discovery by curating findings from primary literature into structured, queryable formats for both human researchers and emerging AI systems. Maintaining these resources requires expert curators to…

Artificial Intelligence · Computer Science 2026-02-11 Xingjian Zhang , Sophia Moylan , Ziyang Xiong , Qiaozhu Mei , Yichen Luo , Jiaqi W. Ma

AI agents powered by large language models exhibit strong reasoning and problem-solving capabilities, enabling them to assist scientific research tasks such as formula derivation and code generation. However, whether these agents can…

Understanding cell identity and function through single-cell level sequencing data remains a key challenge in computational biology. We present a novel framework that leverages gene-specific textual annotations from the NCBI Gene database…

Genomics · Quantitative Biology 2025-05-14 Douglas Jiang , Zilin Dai , Luxuan Zhang , Qiyi Yu , Haoqi Sun , Feng Tian

We introduce SWE-PRBench, a benchmark of 350 pull requests with human-annotated ground truth for evaluating AI code review quality. Evaluated against an LLM-as-judge framework validated at kappa=0.75, 8 frontier models detect only 15-31% of…

Software Engineering · Computer Science 2026-03-30 Deepak Kumar

Autonomous scientific research is significantly advanced thanks to the development of AI agents. One key step in this process is finding the right scientific literature, whether to explore existing knowledge for a research problem, or to…

Data analytics is essential for extracting valuable insights from data that can assist organizations in making effective decisions. We introduce InsightBench, a benchmark dataset with three key features. First, it consists of 100 datasets…