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Layer segmentation is important to quantitative analysis of retinal optical coherence tomography (OCT). Recently, deep learning based methods have been developed to automate this task and yield remarkable performance. However, due to the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Hong Liu , Dong Wei , Donghuan Lu , Xiaoying Tang , Liansheng Wang , Yefeng Zheng

Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Document image segmentation is crucial for document analysis and recognition but remains challenging due to the diversity of document formats and segmentation tasks. Existing methods often address these tasks separately, resulting in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Xiao-Hui Li , Fei Yin , Cheng-Lin Liu

Nucleus segmentation is an important analysis task in digital pathology. However, methods for automatic segmentation often struggle with new data from a different distribution, requiring users to manually annotate nuclei and retrain…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Titus Griebel , Anwai Archit , Constantin Pape

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

As a non-invasive imaging modality, optical coherence tomography (OCT) can provide micrometer-resolution 3D images of retinal structures. Therefore it is commonly used in the diagnosis of retinal diseases associated with edema in and under…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Morgan Heisler , Sieun Lee , Gavin Ding , Marinko V. Sarunic , Mirza Faisal Beg

Foundation models (FMs) have shown great promise in medical image analysis by improving generalization across diverse downstream tasks. In ophthalmology, several FMs have recently emerged, but there is still no clear answer to fundamental…

Visual artefacts of early diabetic retinopathy in retinal fundus images are usually small in size, inconspicuous, and scattered all over retina. Detecting diabetic retinopathy requires physicians to look at the whole image and fixate on…

Computer Vision and Pattern Recognition · Computer Science 2020-06-01 Muhammad Naseer Bajwa , Yoshinobu Taniguchi , Muhammad Imran Malik , Wolfgang Neumeier , Andreas Dengel , Sheraz Ahmed

In ophthalmological imaging, multiple imaging systems, such as color fundus, infrared, fluorescein angiography, optical coherence tomography (OCT) or OCT angiography, are often involved to make a diagnosis of retinal disease. Multi-modal…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Aline Sindel , Bettina Hohberger , Andreas Maier , Vincent Christlein

Among the research efforts to segment the retinal vasculature from fundus images, deep learning models consistently achieve superior performance. However, this data-driven approach is very sensitive to domain shifts. For fundus images, such…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Dewei Hu , Xing Yao , Jiacheng Wang , Yuankai K. Tao , Ipek Oguz

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

Diabetic retinopathy is the most important complication of diabetes. Early diagnosis of retinal lesions helps to avoid visual loss or blindness. Due to high-resolution and small-size lesion regions, applying existing methods, such as…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Zizheng Yan , Xiaoguang Han , Changmiao Wang , Yuda Qiu , Zixiang Xiong , Shuguang Cui

Medical image segmentation is a crucial and time-consuming task in clinical care, where mask precision is extremely important. The Segment Anything Model (SAM) offers a promising approach, as it provides an interactive interface based on…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Julien Khlaut , Elodie Ferreres , Daniel Tordjman , Hélène Philippe , Tom Boeken , Pierre Manceron , Corentin Dancette

In ophthalmology, early fundus screening is an economic and effective way to prevent blindness caused by ophthalmic diseases. Clinically, due to the lack of medical resources, manual diagnosis is time-consuming and may delay the condition.…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Ning Li , Tao Li , Chunyu Hu , Kai Wang , Hong Kang

Automatic segmentation of retinal blood vessels from fundus images plays an important role in the computer aided diagnosis of retinal diseases. The task of blood vessel segmentation is challenging due to the extreme variations in morphology…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Avijit Dasgupta , Sonam Singh

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

Previous foundation models for fundus images were pre-trained with limited disease categories and knowledge base. Here we introduce a knowledge-rich vision-language model (RetiZero) that leverages knowledge from more than 400 fundus…

Diseases such as diabetic retinopathy and age-related macular degeneration pose a significant risk to vision, highlighting the importance of precise segmentation of retinal vessels for the tracking and diagnosis of progression. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Tariq M. Khan , Muhammad Arsalan , Shahzaib Iqbal , Imran Razzak , Erik Meijering

We introduce a new technique for generating retinal fundus images that have anatomically accurate vascular structures, using diffusion models. We generate artery/vein masks to create the vascular structure, which we then condition to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-12 Sojung Go , Younghoon Ji , Sang Jun Park , Soochahn Lee