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The study of the retinal vasculature is a fundamental stage in the screening and diagnosis of many diseases. A complete retinal vascular analysis requires to segment and classify the blood vessels of the retina into arteries and veins…

Image and Video Processing · Electrical Eng. & Systems 2022-09-21 José Morano , Álvaro S. Hervella , Jorge Novo , José Rouco

Accurate retinal vessel segmentation is a challenging problem in color fundus image analysis. An automatic retinal vessel segmentation system can effectively facilitate clinical diagnosis and ophthalmological research. Technically, this…

Image and Video Processing · Electrical Eng. & Systems 2021-03-26 Muyi Sun , Guanhong Zhang

Ophthalmic diseases pose a significant global health burden. However, traditional diagnostic methods and existing monocular image-based deep learning approaches often overlook the pathological correlations between the two eyes. In practical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Guohao Huo , Zibo Lin , Zitong Wang , Ruiting Dai , Hao Tang

Artificial intelligence applied to retinal images offers significant potential for recognizing signs and symptoms of retinal conditions and expediting the diagnosis of eye diseases and systemic disorders. However, developing generalized…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Boa Jang , Youngbin Ahn , Eun Kyung Choe , Chang Ki Yoon , Hyuk Jin Choi , Young-Gon Kim

Purpose: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net) to segment volumetric retinal fluid on optical coherence tomography (OCT) volume. Methods: 3 x 3-mm OCT scans were acquired…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Yukun Guo , Tristan T. Hormel , Honglian Xiong , Jie Wang , Thomas S. Hwang , Yali Jia

The vascular structure of blood vessels is important in diagnosing retinal conditions such as glaucoma and diabetic retinopathy. Accurate segmentation of these vessels can help in detecting retinal objects such as the optic disc and optic…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Abdullah Sarhan , Jon Rokne , Reda Alhajj , Andrew Crichton

Retinal image plays a crucial role in diagnosing various diseases, as retinal structures provide essential diagnostic information. However, effectively capturing structural features while integrating them with contextual information from…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Xinwei Luo , Songlin Zhao , Yun Zong , Yong Chen , Gui-shuang Ying , Lifang He

The development of multi-label deep learning models for retinal disease classification is often hindered by the scarcity of large, expertly annotated clinical datasets due to patient privacy concerns and high costs. The recent release of…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Jerry Cao-Xue , Tien Comlekoglu , Keyi Xue , Guanliang Wang , Jiang Li , Gordon Laurie

Pathologic myopia (PM) is a common blinding retinal degeneration suffered by highly myopic population. Early screening of this condition can reduce the damage caused by the associated fundus lesions and therefore prevent vision loss.…

Image and Video Processing · Electrical Eng. & Systems 2023-05-16 Huihui Fang , Fei Li , Junde Wu , Huazhu Fu , Xu Sun , José Ignacio Orlando , Hrvoje Bogunović , Xiulan Zhang , Yanwu Xu

Accurate vessel segmentation is critical for clinical applications such as disease diagnosis and surgical planning, yet remains challenging due to thin, branching structures and low texture contrast. While foundation models like the Segment…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Suzhong Fu , Rui Sun , Xuan Ding , Jingqi Dong , Yiming Yang , Yao Zhu , Min Chang Jordan Ren , Delin Deng , Angelica Aviles-Rivero , Shuguang Cui , Zhen Li

Over the past decade, generative models have demonstrated success in enhancing fundus images. However, the evaluation of these models remains a challenge. A benchmark for fundus image enhancement is needed for three main reasons:(1)…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Xuanzhao Dong , Wenhui Zhu , Xiwen Chen , Hao Wang , Xin Li , Yujian Xiong , Jiajun Cheng , Zhipeng Wang , Shao Tang , Oana Dumitrascu , Yalin Wang

The joint interpretation of multi-modal and multi-view fundus images is critical for retinopathy prevention, as different views can show the complete 3D eyeball field and different modalities can provide complementary lesion areas. Compared…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Yonghao Huang , Leiting Chen , Chuan Zhou

Detecting retinal image analysis, particularly the geometrical features of branching points, plays an essential role in diagnosing eye diseases. However, existing methods used for this purpose often are coarse-level and lack fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Hao Wang , Wenhui Zhu , Jiayou Qin , Xin Li , Oana Dumitrascu , Xiwen Chen , Peijie Qiu , Abolfazl Razi

The retinal vascular condition is a reliable biomarker of several ophthalmologic and cardiovascular diseases, so automatic vessel segmentation may be crucial to diagnose and monitor them. In this paper, we propose a novel method that…

Image and Video Processing · Electrical Eng. & Systems 2018-12-21 Américo Oliveira , Sérgio Pereira , Carlos A. Silva

Automated segmentation of retinal blood vessels in label-free fundus images entails a pivotal role in computed aided diagnosis of ophthalmic pathologies, viz., diabetic retinopathy, hypertensive disorders and cardiovascular diseases. The…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Avisek Lahiri , Abhijit Guha Roy , Debdoot Sheet , Prabir Kumar Biswas

Retinal disease diagnosis is critical in preventing vision loss and reducing socioeconomic burdens. Globally, over 2.2 billion people are affected by some form of vision impairment, resulting in annual productivity losses estimated at $411…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Youssef Sabiri , Walid Houmaidi , Amine Abouaomar

Retinal vessel segmentation plays a vital role in analyzing fundus images for the diagnosis of systemic and ocular diseases. Building on this, classifying segmented vessels into arteries and veins (A/V) further enables the extraction of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Shuang Zeng , Chee Hong Lee , Kaiwen Li , Boxu Xie , Ourui Fu , Hangzhou He , Lei Zhu , Yanye Lu , Fangxiao Cheng

Diabetic Retinopathy (DR) is a leading cause of vision loss globally. Yet despite its prevalence, the majority of affected people lack access to the specialized ophthalmologists and equipment required for assessing their condition. This can…

Computer Vision and Pattern Recognition · Computer Science 2021-10-22 Alexandros Papadopoulos , Fotis Topouzis , Anastasios Delopoulos

Vessel segmentation of retinal images is a key diagnostic capability in ophthalmology. This problem faces several challenges including low contrast, variable vessel size and thickness, and presence of interfering pathology such as…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Venkateswararao Cherukuri , Vijay Kumar BG , Raja Bala , Vishal Monga

The segmentation of retinal vessels is of significance for doctors to diagnose the fundus diseases. However, existing methods have various problems in the segmentation of the retinal vessels, such as insufficient segmentation of retinal…

Computer Vision and Pattern Recognition · Computer Science 2018-05-14 Yun Jiang , Ning Tan