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Randomized controlled trials generate experimental variation that can credibly identify causal effects, but often suffer from limited scale, while observational datasets are large, but often violate desired identification assumptions. To…

Econometrics · Economics 2023-12-27 George Z. Gui

Fast and accurate sampling method is in high demand, in order to bridge the large gaps between molecular dynamic simulations and experimental observations. Recently, integrated tempering enhanced sampling method (ITS) has been proposed and…

Numerical Analysis · Mathematics 2018-06-22 Zhiyi You , Liying Li , Jianfeng Lu , Hao Ge

Guided exploration with expert demonstrations improves data efficiency for reinforcement learning, but current algorithms often overuse expert information. We propose a novel algorithm to speed up Q-learning with the help of a limited…

Machine Learning · Computer Science 2022-10-06 Fengdi Che , Xiru Zhu , Doina Precup , David Meger , Gregory Dudek

In the pursuit of novel catalyst development to address pressing environmental concerns and energy demand, conventional design and optimization methods often fall short due to the complexity and vastness of the catalyst parameter space. The…

Chemical Physics · Physics 2024-02-08 Nung Siong Lai , Yi Shen Tew , Xialin Zhong , Jun Yin , Jiali Li , Binhang Yan , Xiaonan Wang

In the field of materials science, comprehending material properties is often hindered by the complexity of datasets originating from various sources. This study introduces the Automated Model Training (AMT) Graphical User Interface (GUI),…

Materials Science · Physics 2024-08-06 Mohamed Bilal Shakeel , Samir Brahim Belhaouari , Fedwa El Mellouhi

Application of artificial intelligence (AI), and more specifically machine learning, to the physical sciences has expanded significantly over the past decades. In particular, science-informed AI, also known as scientific AI or inductive…

Artificial intelligence (AI) has emerged as a powerful tool to enhance decision-making and optimize treatment protocols in in vitro fertilization (IVF). In particular, AI shows significant promise in supporting decision-making during the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Jana Zakall , Birgit Pohn , Antonia Graf , Daniel Kovatchki , Arezoo Borji , Ragib Shahriar Islam , Hossam Haick , Heinz Strohmer , Sepideh Hatamikia

In this paper, we introduce a novel quantum algorithm for the factorization of composite odd numbers. This work makes two significant contributions. First, we present a new improvement to the classical Fermat method, fourfold reducing the…

Cryptography and Security · Computer Science 2025-08-15 Julien Mellaerts

We study a hardware-efficient variational quantum algorithm ansatz tailored for the trapped-ion quantum simulator, HEA-TI. We leverage programmable single-qubit rotations and global spin-spin interactions among all ions, reducing the…

Quantum Physics · Physics 2024-07-04 J. -Z. Zhuang , Y. -K. Wu , L. -M. Duan

Accurately predicting protein-ligand binding free energies (BFEs) remains a central challenge in drug discovery, particularly because the most reliable methods, such as free energy perturbation (FEP), are computationally intensive and…

Chemical Physics · Physics 2025-12-09 Farzad Molani , Art E. Cho

The computational cost of exact methods for quantum simulation using classical computers grows exponentially with system size. As a consequence, these techniques can only be applied to small systems. By contrast, we demonstrate that quantum…

Quantum Physics · Physics 2008-12-17 Ivan Kassal , Stephen P. Jordan , Peter J. Love , Masoud Mohseni , Alán Aspuru-Guzik

While real quantum devices have been increasingly used to conduct research focused on achieving quantum advantage or quantum utility in recent years, executing deep quantum circuits or performing quantum machine learning with large-scale…

Quantum Physics · Physics 2026-04-06 Yoshiaki Kawase

Quantum algorithms for simulating electronic ground states are slower than popular classical mean-field algorithms such as Hartree-Fock and density functional theory, but offer higher accuracy. Accordingly, quantum computers have been…

The increasing prevalence of AI-generated content alongside human-written text underscores the need for reliable discrimination methods. To address this challenge, we propose a novel framework with textual embeddings from Pre-trained…

Computation and Language · Computer Science 2024-11-04 Arjun Ramesh Kaushik , Sunil Rufus R P , Nalini Ratha

Quantum algorithms for simulation of Hamiltonian evolution are often based on product formulae. The fractal methods give a systematic way to find arbitrarily high-order product formulae, but result in a large number of exponentials. On the…

Self-driving labs are transforming drug discovery by enabling automated, AI-guided experimentation, but they face challenges in orchestrating complex workflows, integrating diverse instruments and AI models, and managing data efficiently.…

Software Engineering · Computer Science 2025-04-02 Yao Fehlis , Paul Mandel , Charles Crain , Betty Liu , David Fuller

We report the realization of a nuclear magnetic resonance computer with three quantum bits that simulates an adiabatic quantum optimization algorithm. Adiabatic quantum algorithms offer new insight into how quantum resources can be used to…

Quantum Physics · Physics 2007-05-23 Matthias Steffen , Wim van Dam , Tad Hogg , Greg Breyta , Isaac Chuang

Advances in deep learning have opened an era of abundant and accurate predicted protein structures; however, similar progress in protein ensembles has remained elusive. This review highlights several recent research directions towards…

Biomolecules · Quantitative Biology 2025-09-23 Bowen Jing , Bonnie Berger , Tommi Jaakkola

An artificial intelligence (AI) model can be viewed as a function that maps inputs to outputs in high-dimensional spaces. Once designed and well trained, the AI model is applied for inference. However, even optimized AI models can produce…

Artificial Intelligence · Computer Science 2026-02-27 Sha Hu

The implementation of modern monitoring systems for power quality disturbances have the potential to generate substantial amounts of data, reaching a point where transmission and storage of high-frequency measurements become impractical.…

Systems and Control · Electrical Eng. & Systems 2024-07-02 Markus Stroot , Stefan Seiler , Philipp Lutat , Andreas Ulbig
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