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Designing quantum algorithms is a complex and counterintuitive task, making it an ideal candidate for AI-driven algorithm discovery. To this end, we employ the Hive, an AI platform for program synthesis, which utilises large language models…

Accurately computing the free energies of biological processes is a cornerstone of computer-aided drug design but it is a daunting task. The need to sample vast conformational spaces and account for entropic contributions makes the…

We introduce a new Adaptive Integration Approach (AIA) to be used in a wide range of molecular simulations. Given a simulation problem and a step size, the method automatically chooses the optimal scheme out of an available family of…

Numerical Analysis · Computer Science 2016-11-23 Mario Fernández-Pendás , Elena Akhmatskaya , J. M. Sanz-Serna

Quantum annealing method has been widely attracted attention in statistical physics and information science since it is expected to be a powerful method to obtain the best solution of optimization problem as well as simulated annealing. The…

Disordered Systems and Neural Networks · Physics 2017-08-23 Shu Tanaka , Ryo Tamura

We study two hybridization algorithms used for the combination of a quantum inertial sensor based on atom interferometry with a classical inertial sensor for onboard acceleration measurements. The first is based on the direct extraction of…

In biomolecular systems (especially all-atom models) with many degrees of freedom such as proteins and nucleic acids, there exist an astronomically large number of local-minimum-energy states. Conventional simulations in the canonical…

Statistical Mechanics · Physics 2010-12-30 Ayori Mitsutake , Yoshiharu Mori , Yuko Okamoto

To enhance the performance of quantum annealing machines, several methods have been proposed to reduce the number of spins by fixing spin values through preprocessing. We proposed a hybrid optimization method that combines a simulated…

Statistical Mechanics · Physics 2025-07-22 Shuta Kikuchi , Nozomu Togawa , Shu Tanaka

Traditional network experiments focus on validation through either simulation or emulation. Each approach has its own advantages and limitations. In this work, we present a new tool for next-generation network experiments created through…

Networking and Internet Architecture · Computer Science 2026-03-26 Majd Latah , Kubra Kalkan

Quantum-inspired classical algorithms has received much attention due to its exponential speedup compared to existing algorithms, under certain data storage assumptions. The improvements are noticeable in fundamental linear algebra tasks.…

Quantum Physics · Physics 2025-12-08 Hyunho Cha , Jungwoo Lee

The quantum approximate optimisation algorithm (QAOA) is at the core of many scenarios that aim to combine the power of quantum computers and classical high-performance computing appliances for combinatorial optimisation. Several obstacles…

Quantum Physics · Physics 2026-02-26 Simon Thelen , Hila Safi , Wolfgang Mauerer

High-throughput computational materials discovery has promised significant acceleration of the design and discovery of new materials for many years. Despite a surge in interest and activity, the constraints imposed by large-scale…

High precision measurements are essential to solve major scientific and technological challenges, from gravitational wave detection to healthcare diagnostics. Quantum sensing delivers greater precision, but an in-depth optimisation of…

The generation of molecules with Artificial Intelligence (AI) is poised to revolutionize materials discovery. Potential applications range from development of potent drugs to efficient carbon capture and separation technologies. However,…

Quantum computing leverages the unique properties of qubits and quantum parallelism to solve problems intractable for classical systems, offering unparalleled computational potential. However, the optimization of quantum circuits remains…

Hybrid quantum mechanical-molecular mechanical (QM/MM) simulations are widely used in enzyme simulation. Over ten convergence studies of QM/MM methods have revealed over the past several years that key energetic and structural properties…

Chemical Physics · Physics 2017-01-11 Maria Karelina , Heather J. Kulik

Recently, various Artificial Intelligence (AI) based optimization metaheuristics are proposed and applied for a variety of problems. Cohort Intelligence (CI) algorithm is a socio inspired optimization technique which is successfully applied…

Neural and Evolutionary Computing · Computer Science 2023-10-17 Aniket Nargundkar , Madhav Rawal , Aryaman Patel , Anand J Kulkarni , Apoorva S Shastri

This review describes recent advances by the authors and others on the topic of incorporating experimental data into molecular simulations through maximum entropy methods. Methods which incorporate experimental data improve accuracy in…

Chemical Physics · Physics 2019-05-15 Dilnoza B. Amirkulova , Andrew D. White

With advances in scientific computing, computer experiments are increasingly used for optimizing complex systems. However, for modern applications, e.g., the optimization of nuclear physics detectors, each experiment run can require…

Machine Learning · Statistics 2025-08-08 Hwanwoo Kim , Simon Mak , Ann-Kathrin Schuetz , Alan Poon

The ability of quantum computers to overcome the exponential memory scaling of many-body problems is expected to transform quantum chemistry. Quantum algorithms require accurate representations of electronic states on a quantum device, but…

Chemical Physics · Physics 2024-04-26 Hugh G. A. Burton

Product formulas can be used to simulate Hamiltonian dynamics on a quantum computer by approximating the exponential of a sum of operators by a product of exponentials of the individual summands. This approach is both straightforward and…

Quantum Physics · Physics 2019-09-04 Andrew M. Childs , Aaron Ostrander , Yuan Su
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