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Diabetic retinopathy (DR), a microvascular complication of diabetes and a leading cause of preventable blindness, is projected to affect more than 130 million individuals worldwide by 2030. Early identification is essential to reduce…

Quantitative Methods · Quantitative Biology 2025-11-12 Jophy Lin

The retina provides a unique, noninvasive window into Alzheimer's disease (AD) and dementia, capturing early structural changes through morphometric features, while systemic and lifestyle risk factors reflect well-established contributors…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Seowung Leem , Lin Gu , Chenyu You , Kuang Gong , Ruogu Fang

Preprint Note: This is the author preprint version of a paper accepted for presentation at the IISE Annual Conference & Expo 2025. The final version will appear in the official proceedings. Diabetic retinopathy (DR) is a leading cause of…

Machine Learning · Computer Science 2025-10-02 Mahyar Mahmoudi , Tieming Liu

Retinopathy of Prematurity (ROP) is an eye disorder primarily affecting premature infants with lower weights. It causes proliferation of vessels in the retina and could result in vision loss and, eventually, retinal detachment, leading to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Alexander Ding , Qilei Chen , Yu Cao , Benyuan Liu

Preventable or undiagnosed visual impairment and blindness affect billion of people worldwide. Automated multi-disease detection models offer great potential to address this problem via clinical decision support in diagnosis. In this work,…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Dominik Müller , Iñaki Soto-Rey , Frank Kramer

Alzheimer's disease (AD) constitutes a complex neurocognitive disease and is the main cause of dementia. Although many studies have been proposed targeting at diagnosing dementia through spontaneous speech, there are still limitations.…

Computation and Language · Computer Science 2023-08-24 Loukas Ilias , Dimitris Askounis

Diabetic retinopathy is a leading cause of blindness in diabetic patients and early detection plays a crucial role in preventing vision loss. Traditional diagnostic methods are often time-consuming and prone to errors. The emergence of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Saif Ur Rehman Khan , Muhammad Nabeel Asim , Sebastian Vollmer , Andreas Dengel

Diabetic retinopathy (DR) is a complication of diabetes, and one of the major causes of vision impairment in the global population. As the early-stage manifestation of DR is usually very mild and hard to detect, an accurate diagnosis via…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Yuhan Zheng , Fuping Wu , Bartłomiej W. Papież

Diabetic retinopathy (DR) is a leading cause of preventable blindness worldwide, demanding accurate automated diagnostic systems. While general-domain vision-language models like Contrastive Language-Image Pre-Training (CLIP) perform well…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Argha Kamal Samanta , Harshika Goyal , Vasudha Joshi , Tushar Mungle , Pabitra Mitra

A major cause of irreversible visual impairment is angle-closure glaucoma, which can be screened through imagery from Anterior Segment Optical Coherence Tomography (AS-OCT). Previous computational diagnostic techniques address this…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Huazhu Fu , Yanwu Xu , Stephen Lin , Damon Wing Kee Wong , Baskaran Mani , Meenakshi Mahesh , Tin Aung , Jiang Liu

Alzheimer's Disease (AD) is a progressive neurological disorder that can result in significant cognitive impairment and dementia. Accurate and timely diagnosis is essential for effective treatment and management of this disease. In this…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Mozhgan Naderi , Maryam Rastgarpour , Amir Reza Takhsha

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Accurate segmentation of retinal images plays a crucial role in aiding ophthalmologists in diagnosing retinopathy of prematurity (ROP) and assessing its severity. However, due to their underdeveloped, thinner vessels, manual annotation in…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Gozde Merve Demirci , Jiachen Yao , Ming-Chih Ho , Xiaoling Hu , Wei-Chi Wu , Chao Chen , Chia-Ling Tsai

Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Mohammad Rahimzadeh , Mahmoud Reza Mohammadi

Independent indoor mobility remains a critical challenge for individuals with visual impairments, largely due to the limited capability of existing assistive systems in detecting fine-grained hazardous objects such as chairs, tables, and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Qi He , XiangXiang Wang , Jingtao Zhang , Yongbin Yu , Hongxiang Chu , Manping Fan , JingYe Cai , Zhenglin Yang

Glaucoma is a leading cause of irreversible blindness, but early detection can significantly improve treatment outcomes. Traditional diagnostic methods are often invasive and require specialized equipment. In this work, we present a deep…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Rishiraj Paul Chowdhury , Nirmit Shekar Karkera

The collaborative reasoning for understanding each image-question pair is very critical but under-explored for an interpretable Visual Question Answering (VQA) system. Although very recent works also tried the explicit compositional…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 Qingxing Cao , Xiaodan Liang , Bailing Li , Guanbin Li , Liang Lin

Retinopathy of prematurity (ROP) is an abnormal blood vessel development in the retina of a prematurely-born infant or an infant with low birth weight. ROP is one of the leading causes for infant blindness globally. Early detection of ROP…

Image and Video Processing · Electrical Eng. & Systems 2020-06-15 Xin Guo , Yusuke Kikuchi , Guan Wang , Jinglin Yi , Qiong Zou , Rui Zhou

Most of the existing deep learning based methods for vessel segmentation neglect two important aspects of retinal vessels, one is the orientation information of vessels, and the other is the contextual information of the whole fundus…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Xinxu Wei , Kaifu Yang , Danilo Bzdok , Yongjie Li

Large vision-language models (LVLMs) are typically trained using autoregressive language modeling objectives, which align visual representations with linguistic space. While effective for multimodal reasoning, this alignment can weaken…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Donghee Lee , Rui Cai , Zhe Zhao
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