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Network inference, the task of reconstructing interactions in a complex system from experimental observables, is a central yet extremely challenging problem in systems biology. While much progress has been made in the last two decades,…

Quantitative Methods · Quantitative Biology 2024-09-12 Stephen Y Zhang

Causal representation learning (CRL) offers the promise of uncovering the underlying causal model by which observed data was generated, but the practical applicability of existing methods remains limited by the strong assumptions required…

Machine Learning · Computer Science 2026-01-30 Yuhang Liu , Zhen Zhang , Dong Gong , Erdun Gao , Biwei Huang , Mingming Gong , Anton van den Hengel , Kun Zhang , Javen Qinfeng Shi

Individual contributions to the spread of an epidemic vary widely due to an individual's location in a social network and their intrinsic ability to spread or contract diseases. While the effect of heterogeneous population structure and…

Populations and Evolution · Quantitative Biology 2026-05-14 Abhay Gupta , Nicholas W. Landry

This paper addresses the problem of transferring useful knowledge from a source network to predict node labels in a newly formed target network. While existing transfer learning research has primarily focused on vector-based data, in which…

Machine Learning · Computer Science 2016-11-15 Meng Fang , Jie Yin , Xingquan Zhu

Medical imaging models frequently fail when deployed across hospitals, scanners, populations, or imaging protocols due to domain shift, limiting their clinical reliability. While transfer learning and domain adaptation address such shifts…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Mohammed M. Abdelsamea , Daniel Tweneboah Anyimadu , Tasneem Selim , Saif Alzubi , Lei Zhang , Ahmed Karam Eldaly , Xujiong Ye

Social network structures play an important role in the lives of animals by affecting individual fitness and the spread of disease and information. Nevertheless, we still lack a good understanding of how these structures emerge from the…

Physics and Society · Physics 2026-02-16 Josefine Bohr Brask , Andreas Koher , Darren P. Croft , Sune Lehmann

Cyber-physical systems come with increasingly complex architectures and failure modes, which complicates the task of obtaining accurate system reliability models. At the same time, with the emergence of the (industrial) Internet-of-Things,…

Formal Languages and Automata Theory · Computer Science 2019-09-16 Alexis Linard , Doina Bucur , Marielle Stoelinga

Causality understanding between events is a critical natural language processing task that is helpful in many areas, including health care, business risk management and finance. On close examination, one can find a huge amount of textual…

Computation and Language · Computer Science 2021-02-01 Vivek Khetan , Roshni Ramnani , Mayuresh Anand , Shubhashis Sengupta , Andrew E. Fano

Latent tree learning models represent sentences by composing their words according to an induced parse tree, all based on a downstream task. These models often outperform baselines which use (externally provided) syntax trees to drive the…

Computation and Language · Computer Science 2020-01-16 Jean Maillard , Stephen Clark

Causal inference using observational text data is becoming increasingly popular in many research areas. This paper presents the Bayesian Topic Regression (BTR) model that uses both text and numerical information to model an outcome…

Machine Learning · Statistics 2021-09-14 Maximilian Ahrens , Julian Ashwin , Jan-Peter Calliess , Vu Nguyen

Causal representation learning aims to unveil latent high-level causal representations from observed low-level data. One of its primary tasks is to provide reliable assurance of identifying these latent causal models, known as…

Machine Learning · Computer Science 2024-12-02 Yuhang Liu , Zhen Zhang , Dong Gong , Mingming Gong , Biwei Huang , Anton van den Hengel , Kun Zhang , Javen Qinfeng Shi

Evolutionary methods have long been useful for analysis and explanation in genetics, biology, ecology, and related fields. In this work, we extend these methods to neural networks, specifically large language models (LLMs), to better…

Neural and Evolutionary Computing · Computer Science 2026-05-06 Shannon K. Gallagher , Swati Rallapalli , Tyler Brooks , Chuck Loughin , Michele Sezgin , Ronald Yurko

The discovery of causal relationships is a fundamental problem in science and medicine. In recent years, many elegant approaches to discovering causal relationships between two variables from observational data have been proposed. However,…

Machine Learning · Statistics 2021-06-22 Ciarán M. Lee , Christopher Hart , Jonathan G. Richens , Saurabh Johri

Vector-borne diseases often infect multiple host species, increasing the likelihood of disease persistence due to the presence of multiple reservoirs. Vector biting patterns and feeding preferences can shift in response to selective…

Populations and Evolution · Quantitative Biology 2026-05-01 Shravani Shetgaonkar , Anupama Sharma

Early estimates of the transmission properties of a newly emerged pathogen are critical to an effective public health response, and are often based on limited outbreak data. Here, we use simulations to investigate a potential source of bias…

Populations and Evolution · Quantitative Biology 2022-11-17 Thomas Harris , Nicholas Geard , Cameron Zachreson

The "reversal curse" refers to the phenomenon where large language models (LLMs) exhibit predominantly unidirectional behavior when processing logically bidirectional relationships. Prior work attributed this to autoregressive training --…

Computation and Language · Computer Science 2026-01-13 Shaokai He , Kaiwen Wei , Xinyi Zeng , Xiang Chen , Xue Yang , Zhenyang Li , Jiang Zhong , Yu Tian

We introduce a novel framework for temporal causal discovery and inference that addresses two key challenges: complex nonlinear dependencies and spurious correlations. Our approach employs a multi-layer Transformer-based time-series…

Machine Learning · Computer Science 2025-08-25 Jihua Huang , Yi Yao , Ajay Divakaran

Recent work has shown promising results in causal discovery by leveraging interventional data with gradient-based methods, even when the intervened variables are unknown. However, previous work assumes that the correspondence between…

Machine Learning · Computer Science 2022-07-12 Gonçalo R. A. Faria , André F. T. Martins , Mário A. T. Figueiredo

Classical machine learning techniques often struggle with overfitting and unreliable predictions when exposed to novel conditions. Introducing causality into the modelling process offers a promising way to mitigate these challenges by…

Computational Engineering, Finance, and Science · Computer Science 2025-05-28 David Zapata Gonzalez , Marcel Meyer , Oliver Mueller

Statistical learning relies upon data sampled from a distribution, and we usually do not care what actually generated it in the first place. From the point of view of causal modeling, the structure of each distribution is induced by…

Machine Learning · Computer Science 2018-09-11 Giambattista Parascandolo , Niki Kilbertus , Mateo Rojas-Carulla , Bernhard Schölkopf
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