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Automatic extraction of medical information from clinical documents poses several challenges: high costs of required clinical expertise, limited interpretability of model predictions, restricted computational resources and privacy…

Causal relation extraction (CRE) is central to biomedical text mining, but current resources often conflate causal relations with broader associations, restrict annotation to sentence-level examples, or focus mainly on explicit causal cues.…

Computation and Language · Computer Science 2026-05-28 Ifeoluwa Kunle-John , Josiah Paul , Oluwatosin Agbaakin , Peter Aina , Ikenna Odezuligbo , Sydney Anuyah

Large language models (LLMs) achieve high accuracy in medical diagnosis when all clinical information is provided in a single turn, yet how they behave under multi-turn evidence accumulation closer to real clinical reasoning remains…

Computation and Language · Computer Science 2026-04-07 Jinrui Fang , Runhan Chen , Xu Yang , Jian Yu , Jiawei Xu , Ashwin Vinod , Wenqi Shi , Tianlong Chen , Heng Ji , ChengXiang Zhai , Ying Ding , Yuji Zhang

Predicting Mild Cognitive Impairment (MCI) is currently a challenge as existing diagnostic criteria rely on neuropsychological examinations. Automated Machine Learning (ML) models that are trained on verbal utterances of MCI patients can…

Computation and Language · Computer Science 2015-12-11 Sylvester Olubolu Orimaye , Kah Yee Tai , Jojo Sze-Meng Wong , Chee Piau Wong

An accurate and detailed account of patient medications, including medication changes within the patient timeline, is essential for healthcare providers to provide appropriate patient care. Healthcare providers or the patients themselves…

Large Language Models (LLMs) have emerged as powerful candidates to inform clinical decision-making processes. While these models play an increasingly prominent role in shaping the digital landscape, two growing concerns emerge in…

Computation and Language · Computer Science 2024-04-24 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Large language models are meticulously aligned to be both helpful and harmless. However, recent research points to a potential overkill which means models may refuse to answer benign queries. In this paper, we investigate the factors for…

Computation and Language · Computer Science 2024-02-01 Chenyu Shi , Xiao Wang , Qiming Ge , Songyang Gao , Xianjun Yang , Tao Gui , Qi Zhang , Xuanjing Huang , Xun Zhao , Dahua Lin

Selective labels occur when label observations are subject to a decision-making process; e.g., diagnoses that depend on the administration of laboratory tests. We study a clinically-inspired selective label problem called disparate…

Machine Learning · Computer Science 2024-06-28 Trenton Chang , Jenna Wiens

Large Language Models (LLMs) are increasingly used for medical entity extraction, yet their confidence scores are often miscalibrated, limiting safe deployment in clinical settings. We present a conformal prediction framework that provides…

Computation and Language · Computer Science 2026-03-10 Manil Shrestha , Edward Kim

Clinical coding is the task of assigning a set of alphanumeric codes, referred to as ICD (International Classification of Diseases), to a medical event based on the context captured in a clinical narrative. The latest version of ICD,…

Computation and Language · Computer Science 2022-03-11 Cansu Sen , Bingyang Ye , Javed Aslam , Amir Tahmasebi

Supervised topic models can help clinical researchers find interpretable cooccurence patterns in count data that are relevant for diagnostics. However, standard formulations of supervised Latent Dirichlet Allocation have two problems.…

Machine Learning · Statistics 2016-12-07 Michael C. Hughes , Huseyin Melih Elibol , Thomas McCoy , Roy Perlis , Finale Doshi-Velez

The accurate extraction of medical orders from doctor-patient conversations is a critical task for reducing clinical documentation burdens and ensuring patient safety. This paper details our team submission to the MEDIQA-OE-2025 Shared…

Computation and Language · Computer Science 2025-11-14 Abhinand Balachandran , Bavana Durgapraveen , Gowsikkan Sikkan Sudhagar , Vidhya Varshany J S , Sriram Rajkumar

Medical image analysis requires substantial labeled data for model training, yet expert annotation is expensive and time-consuming. Active learning (AL) addresses this challenge by strategically selecting the most informative samples for…

Image and Video Processing · Electrical Eng. & Systems 2026-03-06 Ifrat Ikhtear Uddin , Longwei Wang , Xiao Qin , Yang Zhou , KC Santosh

Medical synonym identification has been an important part of medical natural language processing (NLP). However, in the field of Chinese medical synonym identification, there are problems like low precision and low recall rate. To solve the…

Computation and Language · Computer Science 2018-12-06 K. Lei , S. Si , D. Wen , Y. Shen

Neurological disorders that affect speech production, such as Alzheimer's Disease (AD), significantly impact the lives of both patients and caregivers, whether through social, psycho-emotional effects or other aspects not yet fully…

Objective: Clinical documentation contains factual, diagnostic, and management errors that can compromise patient safety. Large language models (LLMs) may help detect and correct such errors, but their behavior under different prompting…

Computation and Language · Computer Science 2025-11-27 Farzad Ahmed , Joniel Augustine Jerome , Meliha Yetisgen , Özlem Uzuner

The mechanisms underlying scientific confabulation in Large Language Models (LLMs) remain poorly understood. We introduce ReFACT (Reddit False And Correct Texts), a benchmark of 1,001 expert-annotated question-answer pairs with span-level…

Computation and Language · Computer Science 2026-04-24 Yindong Wang , Martin Preiß , Margarita Bugueño , Jan Vincent Hoffbauer , Abdullatif Ghajar , Tolga Buz , Gerard de Melo

Medical dialogue information extraction is becoming an increasingly significant problem in modern medical care. It is difficult to extract key information from electronic medical records (EMRs) due to their large numbers. Previously,…

Computation and Language · Computer Science 2023-03-14 Xinshi Wang , Daniel Tang

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Clinical document metadata, such as document type, structure, author role, medical specialty, and encounter setting, is essential for accurate interpretation of information captured in clinical documents. However, vast documentation…

Computation and Language · Computer Science 2026-01-16 Kurt Miller , Qiuhao Lu , William Hersh , Kirk Roberts , Steven Bedrick , Andrew Wen , Hongfang Liu
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