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DNA sequencing is revolutionising the field of medicine. DNA sequencers, the machines which perform DNA sequencing, have evolved from the size of a fridge to that of a mobile phone over the last two decades. The cost of sequencing a human…

Genomics · Quantitative Biology 2021-01-14 Hasindu Gamaarachchi

DNA storage technology offers new possibilities for addressing massive data storage due to its high storage density, long-term preservation, low maintenance cost, and compact size. To improve the reliability of stored information, base…

Machine Learning · Computer Science 2024-09-24 Bowen Liu , Jiankun Li

Optical character recognition (OCR) is crucial for a deeper access to historical collections. OCR needs to account for orthographic variations, typefaces, or language evolution (i.e., new letters, word spellings), as the main source of…

Computation and Language · Computer Science 2021-02-02 Lijun Lyu , Maria Koutraki , Martin Krickl , Besnik Fetahu

Recent advancements in vision-language models (VLMs) have improved performance by increasing the number of visual tokens, which are often significantly longer than text tokens. However, we observe that most real-world scenarios do not…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Senqiao Yang , Junyi Li , Xin Lai , Bei Yu , Hengshuang Zhao , Jiaya Jia

Large Language Models (LLMs) have achieved remarkable success in source code understanding, yet as software systems grow in scale, computational efficiency has become a critical bottleneck. Currently, these models rely on a text-based…

Computation and Language · Computer Science 2026-04-29 Yuling Shi , Chaoxiang Xie , Zhensu Sun , Yeheng Chen , Chenxu Zhang , Longfei Yun , Chengcheng Wan , Hongyu Zhang , David Lo , Xiaodong Gu

Object-Centric Learning (OCL) represents dense image or video pixels as sparse object features. Representative methods utilize discrete representation composed of Variational Autoencoder (VAE) template features to suppress pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Rongzhen Zhao , Vivienne Wang , Juho Kannala , Joni Pajarinen

Existing vision-language models exhibit strong generalization on a variety of visual domains and tasks. However, such models mainly perform zero-shot recognition in a closed-set manner, and thus struggle to handle open-domain visual…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Yuhang Zang , Hanlin Goh , Josh Susskind , Chen Huang

Optical coherence tomography angiography (OCTA) is a non-invasive imaging technique widely used to study vascular structures and micro-circulation dynamics in the retina and choroid. OCTA has been widely used in clinics for diagnosing…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Kejie Chen , Guanbing Gao , Xiaochun Yang , Wenbo Wang , Jing Na

The integration of multi-omic data is pivotal for understanding complex diseases, but its high dimensionality and noise present significant challenges. Graph Neural Networks (GNNs) offer a robust framework for analyzing large-scale…

Quantitative Methods · Quantitative Biology 2024-12-23 Heming Zhang , Di Huang , Yixin Chen , Fuhai Li

Tokens serve as the basic units of representation in DNA language models (DNALMs), yet their design remains underexplored. Unlike natural language, DNA lacks inherent token boundaries or predefined compositional rules, making tokenization a…

Machine Learning · Computer Science 2026-04-13 Nan Huang , Xiaoxiao Zhou , Junxia Cui , Mario Tapia-Pacheco , Tiffany Amariuta , Yang Li , Jingbo Shang

The folding structure of the DNA molecule combined with helper molecules, also referred to as the chromatin, is highly relevant for the functional properties of DNA. The chromatin structure is largely determined by the underlying primary…

Machine Learning · Computer Science 2018-06-14 Bojian Yin , Marleen Balvert , Davide Zambrano , Alexander Schönhuth , Sander Bohte

Existing optical character recognition (OCR) methods rely on task-specific designs with divergent paradigms, architectures, and training strategies, which significantly increases the complexity of research and maintenance and hinders the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Dezhi Peng , Zhenhua Yang , Jiaxin Zhang , Chongyu Liu , Yongxin Shi , Kai Ding , Fengjun Guo , Lianwen Jin

Traditional OCR systems (OCR-1.0) are increasingly unable to meet people's usage due to the growing demand for intelligent processing of man-made optical characters. In this paper, we collectively refer to all artificial optical signals…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Haoran Wei , Chenglong Liu , Jinyue Chen , Jia Wang , Lingyu Kong , Yanming Xu , Zheng Ge , Liang Zhao , Jianjian Sun , Yuang Peng , Chunrui Han , Xiangyu Zhang

Modern biological science produces vast amounts of genomic sequence data. This is fuelling the need for efficient algorithms for sequence compression and analysis. Data compression and the associated techniques coming from information…

Data Structures and Algorithms · Computer Science 2011-09-05 Heba Afify , Muhammad Islam , Manal Abdel Wahed

DNA labeling is a powerful tool in molecular biology and biotechnology that allows for the visualization, detection, and study of DNA at the molecular level. Under this paradigm, a DNA molecule is being labeled by specific k patterns and is…

Information Theory · Computer Science 2024-01-24 Dganit Hanania , Daniella Bar-Lev , Yevgeni Nogin , Yoav Shechtman , Eitan Yaakobi

Traditional image compression methods aim to reconstruct images for human perception, prioritizing visual fidelity over task relevance. In contrast, Coding for Machines focuses on preserving information essential for automated…

Image and Video Processing · Electrical Eng. & Systems 2025-10-16 Stefano Della Fiore , Alessandro Gnutti , Marco Dalai , Pierangelo Migliorati , Riccardo Leonardi

The exponential increase in storage demand and low lifespan of data storage devices has resulted in long-term archival and preservation emerging as a critical bottlenecks in data storage. In order to meet this demand, researchers are now…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Xavier Pic , Raja Appuswamy

DeepSeek-OCR utilizes an optical 2D mapping approach to achieve high-ratio vision-text compression, claiming to decode text tokens exceeding ten times the input visual tokens. While this suggests a promising solution for the LLM…

Computation and Language · Computer Science 2026-01-09 Yunhao Liang , Ruixuan Ying , Bo Li , Hong Li , Kai Yan , Qingwen Li , Min Yang , Okamoto Satoshi , Zhe Cui , Shiwen Ni

Optical Coherence Tomography Angiography (OCTA) and its derived en-face projections provide high-resolution visualization of the retinal and choroidal vasculature, which is critical for the rapid and accurate diagnosis of retinal diseases.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Pooya Khosravi , Kun Han , Anthony T. Wu , Arghavan Rezvani , Zexin Feng , Xiaohui Xie

Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…

Image and Video Processing · Electrical Eng. & Systems 2023-01-03 Timothy T. Yu , Da Ma , Jayden Cole , Myeong Jin Ju , Mirza F. Beg , Marinko V. Sarunic
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