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Foundation models are transforming neuroscience but are often prohibitively large, data-hungry, and difficult to deploy. Here, we introduce BrainSymphony, a lightweight and parameter-efficient foundation model with plug-and-play integration…

Quantitative Methods · Quantitative Biology 2026-02-13 Moein Khajehnejad , Forough Habibollahi , Devon Stoliker , Adeel Razi

Brain network analysis provides an interpretable framework for characterizing brain organization and has been widely used for neurological disorder identification. Recent advances in self-supervised learning have motivated the development…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jiaxing Xu , Jingying Ma , Xin Lin , Yuxiao Liu , Kai He , Qika Lin , Yiping Ke , Yang Li , Dinggang Shen , Mengling Feng

Task-evoked functional magnetic resonance imaging studies, such as the Human Connectome Project (HCP), are a powerful tool for exploring how brain activity is influenced by cognitive tasks like memory retention, decision-making, and…

Applications · Statistics 2024-05-22 Michelle F. Miranda

Network data are increasingly collected along with other variables of interest. Our motivation is drawn from neurophysiology studies measuring brain connectivity networks for a sample of individuals along with their membership to a low or…

Methodology · Statistics 2018-09-11 Daniele Durante , David B. Dunson

Human brain functional connectivity (FC) is often measured as the similarity of functional MRI responses across brain regions when a brain is either resting or performing a task. This paper aims to statistically analyze the dynamic nature…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

Machine Learning · Statistics 2015-03-02 Shaurabh Nandy , Richard M. Golden

Analysis of brain connectivity is important for understanding how information is processed by the brain. We propose a novel Bayesian vector autoregression (VAR) hierarchical model for analyzing brain connectivity in a resting-state fMRI…

Applications · Statistics 2021-12-09 Bertil Wegmann , Anders Lundquist , Anders Eklund , Mattias Villani

Functional magnetic resonance imaging (fMRI) is a powerful tool for investigating human brain function. However, the high cost of data acquisition and the inherent subjectivity of psychiatric rating scales often lead to datasets with small…

Machine Learning · Computer Science 2026-05-29 Jiyao Wang , Peiyu Duan , Nicha C. Dvornek , Lawrence H. Staib , Denis Sukhodolsky , Pamela Ventola , James S. Duncan

The construction of brain graphs from functional Magnetic Resonance Imaging (fMRI) data plays a crucial role in enabling graph machine learning for neuroimaging. However, current practices often rely on rigid pipelines that overlook…

Machine Learning · Computer Science 2025-08-19 Qinwen Ge , Roza G. Bayrak , Anwar Said , Catie Chang , Xenofon Koutsoukos , Tyler Derr

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

Neurons and Cognition · Quantitative Biology 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

Spatial whole-brain Bayesian modeling of task-related functional magnetic resonance imaging (fMRI) is a great computational challenge. Most of the currently proposed methods therefore do inference in subregions of the brain separately or do…

Computation · Statistics 2017-01-03 Per Sidén , Anders Eklund , David Bolin , Mattias Villani

In systems and network neuroscience, many common practices in brain connectomic analysis are often not properly scrutinized. One such practice is mapping a predetermined set of sub-circuits, like functional networks (FNs), onto subjects'…

There is increasing appetite for analysing populations of network data due to the fast-growing body of applications demanding such methods. While methods exist to provide readily interpretable summaries of heterogeneous network populations,…

Applications · Statistics 2023-06-21 Anastasia Mantziou , Simon Lunagomez , Robin Mitra

Source localization based on electroencephalography (EEG) has become a widely used neuroimagining technique. However its precision has been shown to be very dependent on how accurately the brain, head and scalp can be electrically modeled…

Medical Physics · Physics 2020-04-22 Lyes Rahmouni , Adrien Merlini , Axelle Pillain , Francesco P. Andriulli

It has become increasingly popular to study the brain as a network due to the realization that functionality cannot be explained exclusively by independent activation of specialized regions. Instead, across a large spectrum of behaviors,…

Neurons and Cognition · Quantitative Biology 2014-07-22 Petko Bogdanov , Nazli Dereli , Danielle S. Bassett , Scott T. Grafton , Ambuj K. Singh

Due to its causal semantics, Bayesian networks (BN) have been widely employed to discover the underlying data relationship in exploratory studies, such as brain research. Despite its success in modeling the probability distribution of…

Computer Vision and Pattern Recognition · Computer Science 2015-06-24 Luping Zhou , Lei Wang , Lingqiao Liu , Philip Ogunbona , Dinggang Shen

Gaussian Graphical Models (GGM) are popularly used in neuroimaging studies based on fMRI, EEG or MEG to estimate functional connectivity, or relationships between remote brain regions. In multi-subject studies, scientists seek to identify…

Methodology · Statistics 2017-05-01 Manjari Narayan , Genevera I. Allen , Steffie Tomson

Theory-of-Mind (ToM) enables humans to infer mental states-such as beliefs, desires, and intentions-forming the foundation of social cognition. However, existing computational ToM methods rely on structured workflows with ToM-specific…

Artificial Intelligence · Computer Science 2026-05-12 Chunhui Zhang , Zhongyu Ouyang , Kwonjoon Lee , Nakul Agarwal , Sean Dae Houlihan , Soroush Vosoughi , Shao-Yuan Lo

Analyzing and understanding the structure of complex relational data is important in many applications including analysis of the connectivity in the human brain. Such networks can have prominent patterns on different scales, calling for a…

Machine Learning · Statistics 2013-11-22 Mikkel N. Schmidt , Tue Herlau , Morten Mørup