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Related papers: Controlling Repetition in Protein Language Models

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We introduce a pioneering methodology for boosting large language models in the domain of protein representation learning. Our primary contribution lies in the refinement process for correlating the over-reliance on co-evolution knowledge,…

Artificial Intelligence · Computer Science 2024-12-05 Yaoyao Xu , Xinjian Zhao , Xiaozhuang Song , Benyou Wang , Tianshu Yu

Inference-time reasoning scaling has significantly advanced the capabilities of Large Language Models (LLMs) in complex problem-solving. A prevalent approach involves external search guided by Process Reward Models (PRMs). However, a…

Machine Learning · Computer Science 2026-02-09 Zeen Song , Zihao Ma , Wenwen Qiang , Changwen Zheng , Gang Hua

Predictive Coding Networks (PCNs) aim to learn a generative model of the world. Given observations, this generative model can then be inverted to infer the causes of those observations. However, when training PCNs, a noticeable pathology is…

Artificial Intelligence · Computer Science 2022-09-02 Paul F Kinghorn , Beren Millidge , Christopher L Buckley

Chemical language models (CLMs) have emerged as promising competitors to popular classical machine learning models for molecular property prediction (MPP) tasks. However, an increasing number of studies have reported inconsistent and…

Machine Learning · Computer Science 2026-03-17 Mohammad Mostafanejad , Paul Saxe , T. Daniel Crawford

With the thriving of pre-trained language model (PLM) widely verified in various of NLP tasks, pioneer efforts attempt to explore the possible cooperation of the general textual information in PLM with the personalized behavioral…

Information Retrieval · Computer Science 2023-11-28 Zekai Qu , Ruobing Xie , Chaojun Xiao , Yuan Yao , Zhiyuan Liu , Fengzong Lian , Zhanhui Kang , Jie Zhou

Learning sentence embeddings in an unsupervised manner is fundamental in natural language processing. Recent common practice is to couple pre-trained language models with unsupervised contrastive learning, whose success relies on augmenting…

Computation and Language · Computer Science 2022-10-20 Qiyu Wu , Chongyang Tao , Tao Shen , Can Xu , Xiubo Geng , Daxin Jiang

While deep generative models show promise for learning inverse protein folding directly from data, the lack of publicly available structure-sequence pairings limits their generalization. Previous improvements and data augmentation efforts…

Artificial Intelligence · Computer Science 2024-07-23 Jiangbin Zheng , Stan Z. Li

Recent advances in protein large language models, such as ProtTeX, represent both side-chain amino acids and backbone structure as discrete token sequences of residue length. While this design enables unified modeling of multimodal protein…

Machine Learning · Computer Science 2025-08-19 Chuanliu Fan , Zicheng Ma , Jun Gao , Nan Yu , Jun Zhang , Ziqiang Cao , Yi Qin Gao , Guohong Fu

Many applications of machine learning methods involve an iterative protocol in which data are collected, a model is trained, and then outputs of that model are used to choose what data to consider next. For example, one data-driven approach…

Machine Learning · Computer Science 2025-04-07 Clara Fannjiang , Stephen Bates , Anastasios N. Angelopoulos , Jennifer Listgarten , Michael I. Jordan

Large language models (LLMs) increasingly serve as automated evaluators, yet they suffer from "self-preference bias": a tendency to favor their own outputs over those of other models. This bias undermines fairness and reliability in…

Computation and Language · Computer Science 2025-09-05 Dani Roytburg , Matthew Bozoukov , Matthew Nguyen , Jou Barzdukas , Simon Fu , Narmeen Oozeer

Recently, there is a growing interest in creating computer-aided design (CAD) models based on user intent, known as controllable CAD generation. Existing work offers limited controllability and needs separate models for different types of…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Zhanwei Zhang , Shizhao Sun , Wenxiao Wang , Deng Cai , Jiang Bian

The Predictive Associative Memory (PAM) framework posits that useful relationships often connect items that co-occur in shared contexts rather than items that appear similar in embedding space. A contrastive MLP trained on co-occurrence…

Machine Learning · Computer Science 2026-03-24 Jason Dury

Pre-trained Language Models (PLMs) have achieved remarkable performance for various language understanding tasks in IR systems, which require the fine-tuning process based on labeled training data. For low-resource scenarios, prompt-based…

Computation and Language · Computer Science 2022-04-04 Ziyun Xu , Chengyu Wang , Minghui Qiu , Fuli Luo , Runxin Xu , Songfang Huang , Jun Huang

It is imperative to ensure the stability of every prediction made by a language model; that is, a language's prediction should remain consistent despite minor input variations, like word substitutions. In this paper, we investigate the…

Computation and Language · Computer Science 2024-06-06 Qian Lou , Xin Liang , Jiaqi Xue , Yancheng Zhang , Rui Xie , Mengxin Zheng

The successful integration of large language models (LLMs) into recommendation systems has proven to be a major breakthrough in recent studies, paving the way for more generic and transferable recommendations. However, LLMs struggle to…

Information Retrieval · Computer Science 2023-11-29 Junyan Qiu , Haitao Wang , Zhaolin Hong , Yiping Yang , Qiang Liu , Xingxing Wang

Self-consistency with chain-of-thought prompting (CoT) has demonstrated remarkable performance gains on various challenging tasks, by utilizing multiple reasoning paths sampled from large language models (LLMs). However, self-consistency…

Computation and Language · Computer Science 2023-11-30 Xinyun Chen , Renat Aksitov , Uri Alon , Jie Ren , Kefan Xiao , Pengcheng Yin , Sushant Prakash , Charles Sutton , Xuezhi Wang , Denny Zhou

Large Language Models (LLMs) are increasingly applied to automate software engineering tasks, including the generation of UML class diagrams from natural language descriptions. While prior work demonstrates that LLMs can produce…

Software Engineering · Computer Science 2026-04-07 Rabia Iftikhar , Andreas Rausch

Recently, large language models (LLMs) have emerged as a groundbreaking technology and their unparalleled text generation capabilities have sparked interest in their application to the fundamental sentence representation learning task.…

Computation and Language · Computer Science 2024-05-20 Huiming Wang , Zhaodonghui Li , Liying Cheng , Soh De Wen , Lidong Bing

Generative modeling for protein engineering is key to solving fundamental problems in synthetic biology, medicine, and material science. We pose protein engineering as an unsupervised sequence generation problem in order to leverage the…

Large Language Models (LLMs) have recently achieved strong performance in software code generation. However, applying them to hardware description languages (HDLs), such as Verilog, remains challenging because high-quality training data are…

Hardware Architecture · Computer Science 2026-04-21 Yan Tan , Tong Liu , Xiangchen Meng , Yangdi Lyu