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The complicated dynamics of the contact line of a moving droplet on a solid substrate often hamper the efficient modeling of microfluidic systems. In particular, the selection of the effective boundary conditions, specifying the contact…

There is a pressing need to better understand how microbial populations respond to antimicrobial drugs, and to find mechanisms to possibly eradicate antimicrobial-resistant cells. The inactivation of antimicrobials by resistant microbes can…

Populations and Evolution · Quantitative Biology 2023-11-16 Lluís Hernández-Navarro , Matthew Asker , Alastair M. Rucklidge , Mauro Mobilia

Environmental heterogeneity can drive genetic heterogeneity in expanding populations; mutant strains may emerge that trade overall growth rate for an improved ability to survive in patches that are hostile to the wild type. This…

Populations and Evolution · Quantitative Biology 2023-03-06 Thomas Tunstall , Tim Rogers , Wolfram Möbius

We consider a trait-structured population subject to mutation, birth and competition of logistic type, where the number of coexisting types may fluctuate. Applying a limit of rare mutations to this population while keeping the population…

Probability · Mathematics 2011-12-05 Nicolas Champagnat , Amaury Lambert

Population dynamics is constrained by the environment, which needs to obey certain conditions to support population growth. We consider a standard model for the evolution of a single species population density, that includes reproduction,…

Populations and Evolution · Quantitative Biology 2016-10-18 E. H. Colombo , C. Anteneodo

Both compressible and incompressible porous medium models are used in the literature to describe the mechanical properties of living tissues. These two classes of models can be related using a stiff pressure law. In the incompressible…

Analysis of PDEs · Mathematics 2020-06-25 Noemi David , Benoît Perthame

This paper is concerned with spatial spreading dynamics of a nonlocal dispersal population model in a shifting environment where the favorable region is shrinking. It is shown that the species will become extinct in the habitat once the…

Analysis of PDEs · Mathematics 2018-03-14 Wan-Tong Li , Jia-Bing Wang , Xiao-Qiang Zhao

We consider a stochastic individual-based model of adaptive dynamics for an asexually reproducing population with mutation, with linear birth and death rates, as well as a density-dependent competition. To depict repeating changes of the…

Populations and Evolution · Quantitative Biology 2025-05-28 Manuel Esser , Anna Kraut

This paper investigates the connection between discrete and continuous models describing prion proliferation. The scaling parameters are interpreted on biological grounds and we establish rigorous convergence statements. We also discuss,…

Analysis of PDEs · Mathematics 2009-07-15 Marie Doumic , Thierry Goudon , Thomas Lepoutre

An organism that is newly introduced into an existing population has a survival probability that is dependent on both the population density of its environment and the competition it experiences with the members of that population.…

Populations and Evolution · Quantitative Biology 2024-12-17 Jason M. Gray , Rowan J. Barker-Clarke , Jacob G. Scott , Michael Hinczewski

Recent methods have been developed to map single-cell lineage statistics to population growth. Because population growth selects for exponentially rare phenotypes, these methods inherently depend on sampling large deviations from finite…

Statistical Mechanics · Physics 2025-01-16 Trevor GrandPre , Ethan Levien , Ariel Amir

Motivated by the observation that anomalous diffusion is a realistic feature in the dynamics of biological populations, we investigate its implications in a paradigmatic model for the evolution of a single species density $u(x,t)$. The…

Biological Physics · Physics 2012-12-05 Eduardo H. Colombo , Celia Anteneodo

We demonstrate that a potential coexists with limit cycle. Here the potential determines the final distribution of population. Our demonstration consists of three steps: We first show the existence of limit from a typical physical sciences…

Chaotic Dynamics · Physics 2007-05-23 X. -M. Zhu , L. Yin , P. Ao

We study a system of self-propelled, proliferating finite-size disks with game-theoretical interactions, where growth rates depend on local population composition. We analyze how these interactions influence spatial distribution,…

Populations and Evolution · Quantitative Biology 2025-03-05 Alejandro Almodóvar , Tobias Galla , Cristóbal López

How motile bacteria move near a surface is a problem of fundamental biophysical interest and is key to the emergence of several phenomena of biological, ecological and medical relevance, including biofilm formation. Solid boundaries can…

Biological Physics · Physics 2019-09-12 Stanislaw Makarchuk , Vasco C. Braz , Nuno A. M. Araújo , Lena Ciric , Giorgio Volpe

We study the effect of discreteness on various models for patterning in bacterial colonies. In a bacterial colony with branching pattern, there are discrete entities - bacteria - which are only two orders of magnitude smaller than the…

Disordered Systems and Neural Networks · Physics 2007-05-23 Inon Cohen , Ido Golding , Yonathan Kozlovsky , Eshel Ben-Jacob

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

Biological Physics · Physics 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein

Tumour invasion is an essential stage of cancer progression. Its main drivers are diffusion and taxis, a directed movement along the gradient of a stimulus. Here we review models with flux limited diffusion and/or taxis which have…

Analysis of PDEs · Mathematics 2022-03-10 Anna Zhigun

Microbial populations generally evolve in volatile environments, under conditions fluctuating between harsh and mild, e.g. as the result of sudden changes in toxin concentration or nutrient abundance. Environmental variability thus shapes…

Populations and Evolution · Quantitative Biology 2023-12-07 Matthew Asker , Lluís Hernández-Navarro , Alastair M. Rucklidge , Mauro Mobilia

We discuss several continuum cell-cell adhesion models based on the underlying microscopic assumptions. We propose an improvement on these models leading to sharp fronts and intermingling invasion fronts between different cell type…

Cell Behavior · Quantitative Biology 2019-01-11 Jose A. Carrillo , Hideki Murakawa , Makoto Sato , Hideru Togashi , Olena Trush