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We investigate the microtubule polymerization dynamics with catastrophe and rescue events for three different confinement scenarios, which mimic typical cellular environments: (i) The microtubule is confined by rigid and fixed walls, (ii)…

Subcellular Processes · Quantitative Biology 2015-05-12 Björn Zelinski , Nina Müller , Jan Kierfeld

Epidemic spreading often occurs in spatially heterogeneous environments, yet how quenched heterogeneity reshapes its onset and critical dynamics remains poorly understood. The diffusive epidemic process, a minimal reaction-diffusion model…

Statistical Mechanics · Physics 2026-03-24 Valentin Anfray , Hong-Yan Shih

Excess pore pressure in granular--fluid mixtures can transiently suppress frictional contacts and dramatically enhance flow mobility, yet its evolution is commonly modeled using constant effective diffusivities. Here we show that the…

Soft Condensed Matter · Physics 2026-04-21 Eric C. P. Breard , Claudia Elijas Parra , Mattia de' Michieli Vitturi

The current paper is concerned with the existence of spreading speeds and linear determinacy for two species competition systems with nonlocal dispersal in time and space periodic habitats. The notion of spreading speed intervals for such a…

Dynamical Systems · Mathematics 2015-12-01 Liang Kong , Nar Rawal , Wenxian Shen

Growth in confined spaces can drive cellular populations through a jamming transition from a fluid-like state to a solid-like state. Experiments have found that jammed budding yeast populations can build up extreme compressive pressures…

Soft Condensed Matter · Physics 2019-05-29 Pawel Gniewek , Carl F Schreck , Oskar Hallatschek

A major goal of modern computational biology is to simulate the collective behaviour of large cell populations starting from the intricate web of molecular interactions occurring at the microscopic level. In this paper we describe a…

Biological Physics · Physics 2007-05-23 Roberto Chignola , Edoardo Milotti

Budding allows virus replication and macromolecular secretion in cells. It involves the formation of a bud, i.e. an outgrowth from the cell membrane that evolves into an envelope. The largest energetic barrier to bud formation is membrane…

Biological Physics · Physics 2022-10-17 Mattia Bacca

We extend the $N$ branching Brownian motions model of population invasion to higher-order asexual reproduction. Increasing reproduction order leads to qualitative changes: invasion fronts generically cease to exist beyond binary…

Populations and Evolution · Quantitative Biology 2026-05-15 Ohad Vilk , Baruch Meerson

As epithelial development or wound closure approaches completion, cell proliferation progressively slows via contact inhibition of proliferation (CIP) - a mechanism understood as being strictly local. Here we report the discovery of…

Cell Behavior · Quantitative Biology 2025-12-16 Liav Daraf , Yael Lavi , Areej Saleem , Daniel Sevilla Sanchez , Yuri Feldman , Lior Atia

The phase separation mechanism of a binary liquid mixture off-critically quenched in its miscibility gap is nucleation and growth, its homogeneous phase reaching a metastable equilibrium state. The successive stages of growth of the…

Statistical Mechanics · Physics 2009-11-18 Jean Colombani , Jacques Bert

Interactions between commuting individuals can lead to large-scale spreading of rumors, ideas, or disease, even though the commuters have no net displacement. The emergent dynamics depend crucially on the commuting distribution of a…

Populations and Evolution · Quantitative Biology 2023-05-30 Aaron Winn , Adam Konkol , Eleni Katifori

The striking variety of macroscopic morphologies displayed by bacterial colonies depends on microscopic environmental and behavioural details in a manner that is currently not well understood. A surprising example is sibling inhibition,…

Cell Behavior · Quantitative Biology 2026-05-15 Dario Buonomo , Francesco Imperi , Fabio Bruni , Marco Polin , Barbara Capone

We introduce two 2D mechanical models reproducing the evolution of two viscous tissues in contact. Their main property is to model the swirling cell motions while keeping the tissues segregated, as observed during vertebrate embryo…

Analysis of PDEs · Mathematics 2022-03-25 Pierre Degond , Sophie Hecht , Michèle Romanos , Ariane Trescases

Most infectious diseases spread on a dynamic network of human interactions. Recent studies of social dynamics have provided evidence that spreading patterns may depend strongly on detailed micro-dynamics of the social system. We have…

Physics and Society · Physics 2015-09-23 Arkadiusz Stopczynski , Alex Sandy Pentland , Sune Lehmann

Numerous experimental studies have demonstrated that the microenvironment is a key regulator influencing the proliferative and migrative potentials of species. Spatial and temporal disturbances lead to adverse and hazardous…

Populations and Evolution · Quantitative Biology 2015-10-07 Venkata. S. K. Manem , Kamran Kaveh , Mohammad Kohandel , Siv Sivaloganathan

We study the interplay of population growth and evolutionary dynamics using a stochastic model based on birth and death events. In contrast to the common assumption of an independent population size, evolution can be strongly affected by…

Populations and Evolution · Quantitative Biology 2012-06-05 Jonas Cremer , Anna Melbinger , Erwin Frey

Understanding flow and transport of bacteria in porous media is crucial to technologies such as bioremediation, biomineralization or enhanced oil recovery. While physicochemical bacteria filtration is well-documented, recent studies showed…

Soft Condensed Matter · Physics 2022-08-24 Marco Dentz , Adama Creppy , Carine Douarche , Eric Clément , Harold Auradou

Developing epithelial tissues coordinate cell proliferation and mechanical forces to achieve proper size and shape. As epithelial cells tightly adhere together to form the confluent tissue, the distribution of cell areas significantly…

Biological Physics · Physics 2026-01-22 Michael F. Staddon , Natalie A. Dye , Marko Popović , Frank Jülicher

Ecological and evolutionary dynamics have been historically regarded as unfolding at broadly separated timescales. However, these two types of processes are nowadays well documented to much more tightly than traditionally assumed,…

Populations and Evolution · Quantitative Biology 2021-11-17 José Camacho Mateu , Matteo Sireci , Miguel A. Muñoz

Coordinated and cooperative motion of cells is essential for embryonic development, tissue morphogenesis, wound healing and cancer invasion. A predictive understanding of the emergent mechanical behaviors in collective cell motion is…

Biological Physics · Physics 2022-10-04 Michael F. Staddon , Michael P. Murrell , Shiladitya Banerjee
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