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Electroencephalogram (EEG) data is crucial for diagnosing mental health conditions but is costly and time-consuming to collect at scale. Synthetic data generation offers a promising solution to augment datasets for machine learning…

Signal Processing · Electrical Eng. & Systems 2025-07-08 Gideon Vos , Maryam Ebrahimpour , Liza van Eijk , Zoltan Sarnyai , Mostafa Rahimi Azghadi

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

Synthetic data generation using large language models (LLMs) demonstrates substantial promise in addressing biomedical data challenges and shows increasing adoption in biomedical research. This study systematically reviews recent advances…

Computation and Language · Computer Science 2026-02-18 Hanshu Rao , Weisi Liu , Haohan Wang , I-Chan Huang , Zhe He , Xiaolei Huang

Electronic health records (EHRs) store an extensive array of patient information, encompassing medical histories, diagnoses, treatments, and test outcomes. These records are crucial for enabling healthcare providers to make well-informed…

Computation and Language · Computer Science 2023-08-07 Yu-Neng Chuang , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Recent advances in deep learning and natural language generation have significantly improved image captioning, enabling automated, human-like descriptions for visual content. In this work, we apply these captioning techniques to generate…

Computation and Language · Computer Science 2024-12-06 Amnon Bleich , Antje Linnemann , Bjoern H. Diem , Tim OF Conrad

Background: Population-based cancer registries (PBCRs) manually extract data from unstructured pathology reports, a labor-intensive process where assigning reports to tumor groups can consume 900 person-hours annually for approximately…

Computation and Language · Computer Science 2026-03-20 Lovedeep Gondara , Jonathan Simkin , Shebnum Devji , Gregory Arbour , Raymond Ng

Interest in generative Electrocardiogram-Language Models (ELMs) is growing, as they can produce textual responses conditioned on ECG signals and textual queries. Unlike traditional classifiers that output label probabilities, ELMs are more…

Computation and Language · Computer Science 2025-10-02 Xiaoyu Song , William Han , Tony Chen , Chaojing Duan , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Timely access to laboratory values is critical for clinical decision-making, yet current approaches rely on invasive venous sampling and are intrinsically delayed. Electrocardiography (ECG), as a non-invasive and widely available signal,…

Machine Learning · Computer Science 2025-10-28 Yujie Xiao , Gongzhen Tang , Wenhui Liu , Jun Li , Guangkun Nie , Zhuoran Kan , Deyun Zhang , Qinghao Zhao , Shenda Hong

Clinical electroencephalogram (EEG) analysis rests on a hand-crafted feature catalog refined over decades, \emph{e.g.,} band power, connectivity, complexity, and more. Modern EEG foundation models bypass this catalog, learn directly from…

Artificial Intelligence · Computer Science 2026-05-15 Ling Tang , Qian Chen , Jilin Mei , Houshi Xu , Quanshi Zhang , Jing Shao , Na Zou , Xia Hu , Dongrui Liu

Despite significant recent progress in the area of Brain-Computer Interface (BCI), there are numerous shortcomings associated with collecting Electroencephalography (EEG) signals in real-world environments. These include, but are not…

Quantitative Methods · Quantitative Biology 2019-10-14 Nik Khadijah Nik Aznan , Amir Atapour-Abarghouei , Stephen Bonner , Jason Connolly , Noura Al Moubayed , Toby Breckon

Foundation models for electroencephalography (EEG) signals have recently demonstrated success in learning generalized representations of EEGs, outperforming specialized models in various downstream tasks. However, many of these models lack…

Electronic Health Records (EHRs) contain rich yet complex information, and their automated analysis is critical for clinical decision-making. Despite recent advances of large language models (LLMs) in clinical workflows, their ability to…

Computation and Language · Computer Science 2025-11-26 Yusheng Liao , Chaoyi Wu , Junwei Liu , Shuyang Jiang , Pengcheng Qiu , Haowen Wang , Yun Yue , Shuai Zhen , Jian Wang , Qianrui Fan , Jinjie Gu , Ya Zhang , Yanfeng Wang , Yu Wang , Weidi Xie

Medical consultation dialogues contain critical clinical information, yet their unstructured nature hinders effective utilization in diagnosis and treatment. Traditional methods, relying on rule-based or shallow machine learning techniques,…

Computation and Language · Computer Science 2025-04-24 Shuguang Zhao , Qiangzhong Feng , Zhiyang He , Peipei Sun , Yingying Wang , Xiaodong Tao , Xiaoliang Lu , Mei Cheng , Xinyue Wu , Yanyan Wang , Wei Liang

Listening to heart and lung sounds - auscultation - is one of the first and most fundamental steps in a clinical examination. Despite being fast and non-invasive, it demands years of experience to interpret subtle audio cues. Recent deep…

Machine Learning · Computer Science 2026-03-03 Yishan Wang , Tsai-Ning Wang , Mathias Funk , Aaqib Saeed

Electronic Health Records (EHRs) provide rich longitudinal clinical evidence that is central to medical decision-making, motivating the use of retrieval-augmented generation (RAG) to ground large language model (LLM) predictions. However,…

Artificial Intelligence · Computer Science 2026-01-30 Lang Cao , Qingyu Chen , Yue Guo

The advancement in healthcare has shifted focus toward patient-centric approaches, particularly in self-care and patient education, facilitated by access to Electronic Health Records (EHR). However, medical jargon in EHRs poses significant…

Computation and Language · Computer Science 2024-10-28 Zonghai Yao , Nandyala Siddharth Kantu , Guanghao Wei , Hieu Tran , Zhangqi Duan , Sunjae Kwon , Zhichao Yang , README annotation team , Hong Yu

Radiology Report Generation (RRG) through Vision-Language Models (VLMs) promises to reduce documentation burden, improve reporting consistency, and accelerate clinical workflows. However, their clinical adoption remains limited by the lack…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Marco Salmè , Federico Siciliano , Fabrizio Silvestri , Paolo Soda , Rosa Sicilia , Valerio Guarrasi

Neurological disorders pose major global health challenges, driving advances in brain signal analysis. Scalp electroencephalography (EEG) and intracranial EEG (iEEG) are widely used for diagnosis and monitoring. However, dataset…

Neurons and Cognition · Quantitative Biology 2025-10-24 Jiahe Li , Xin Chen , Fanqi Shen , Junru Chen , Yuxin Liu , Daoze Zhang , Zhizhang Yuan , Fang Zhao , Meng Li , Yang Yang

The success of Multimodal Large Language Models (MLLMs) in the medical auxiliary field shows great potential, allowing patients to engage in conversations using physiological signal data. However, general MLLMs perform poorly in cardiac…

Signal Processing · Electrical Eng. & Systems 2025-04-17 Yubao Zhao , Jiaju Kang , Tian Zhang , Puyu Han , Tong Chen
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