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Related papers: Embracing Aleatoric Uncertainty in Medical Multimo…

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Medical multi-modal learning is critical for integrating information from a large set of diverse modalities. However, when leveraging a high number of modalities in real clinical applications, it is often impractical to obtain full-modality…

Machine Learning · Computer Science 2026-03-03 Chenwei Wu , Zitao Shuai , Liyue Shen

In medical imaging, inter-observer variability among radiologists often introduces label uncertainty, particularly in modalities where visual interpretation is subjective. Lung ultrasound (LUS) is a prime example-it frequently presents a…

Multimodal physiological data powers clinical AI systems from intensive care units to wearable devices, but sensors routinely fail in practice. Two failure modes are common: modality missing, where an entire channel is absent, and…

Machine Learning · Computer Science 2026-05-18 Wugeng Zheng , Ziwen Kan , Tianlong Chen , Chen Chen , Song Wang

Uncertainty quantification (UQ) is a critical aspect of artificial intelligence (AI) systems, particularly in high-risk domains such as healthcare, autonomous systems, and financial technology, where decision-making processes must account…

Multimodal learning typically utilizes multimodal joint loss to integrate different modalities and enhance model performance. However, this joint learning strategy can induce modality imbalance, where strong modalities overwhelm weaker ones…

Machine Learning · Computer Science 2025-09-08 Shijie Wang , Li Zhang , Xinyan Liang , Yuhua Qian , Shen Hu

In real world clinical environments, training and applying deep learning models on multi-modal medical imaging data often struggles with partially incomplete data. Standard approaches either discard missing samples, require imputation or…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Christoph Fürböck , Paul Weiser , Branko Mitic , Philipp Seeböck , Thomas Helbich , Georg Langs

Active learning (AL) in open set scenarios presents a novel challenge of identifying the most valuable examples in an unlabeled data pool that comprises data from both known and unknown classes. Traditional methods prioritize selecting…

Machine Learning · Computer Science 2024-11-14 Chen-Chen Zong , Ye-Wen Wang , Kun-Peng Ning , Hai-Bo Ye , Sheng-Jun Huang

Addressing missing modalities presents a critical challenge in multimodal learning. Current approaches focus on developing models that can handle modality-incomplete inputs during inference, assuming that the full set of modalities are…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Yunpeng Zhao , Cheng Chen , Qing You Pang , Quanzheng Li , Carol Tang , Beng-Ti Ang , Yueming Jin

Multimodal learning integrates information from different modalities to enhance model performance, yet it often suffers from modality imbalance, where dominant modalities overshadow weaker ones during joint optimization. This paper reveals…

Machine Learning · Computer Science 2025-10-17 Xiaoyu Ma , Hao Chen

A common assumption in multimodal learning is the completeness of training data, i.e., full modalities are available in all training examples. Although there exists research endeavor in developing novel methods to tackle the incompleteness…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Mengmeng Ma , Jian Ren , Long Zhao , Sergey Tulyakov , Cathy Wu , Xi Peng

Multi-modal medical image completion has been extensively applied to alleviate the missing modality issue in a wealth of multi-modal diagnostic tasks. However, for most existing synthesis methods, their inferences of missing modalities can…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Xiangxi Meng , Yuning Gu , Yongsheng Pan , Nizhuan Wang , Peng Xue , Mengkang Lu , Xuming He , Yiqiang Zhan , Dinggang Shen

Healthcare foundation models have largely followed paradigms from natural language processing and computer vision, emphasizing large scale pretraining and deterministic representations over heterogeneous clinical data. However, clinical…

Machine Learning · Computer Science 2026-04-07 Qian Zhou , Yuanyun Zhang , Shi Li

In regression tasks, aleatoric uncertainty is commonly addressed by considering a parametric distribution of the output variable, which is based on strong assumptions such as symmetry, unimodality or by supposing a restricted shape. These…

Machine Learning · Computer Science 2019-10-30 Axel Brando , Jose A. Rodríguez-Serrano , Jordi Vitrià , Alberto Rubio

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Early identification of patients at risk for clinical deterioration in the intensive care unit (ICU) remains a critical challenge. Delayed recognition of impending adverse events, including mortality, vasopressor initiation, and mechanical…

Machine Learning · Computer Science 2026-03-17 Binesh Sadanandan

We study the problem of monitoring machine learning models under gradual distribution shifts, where circumstances change slowly over time, often leading to unnoticed yet significant declines in accuracy. To address this, we propose…

Machine Learning · Computer Science 2025-05-13 Alexander Koebler , Thomas Decker , Ingo Thon , Volker Tresp , Florian Buettner

Understanding uncertainty plays a critical role in achieving common ground (Clark et al.,1983). This is especially important for multimodal AI systems that collaborate with users to solve a problem or guide the user through a challenging…

Computation and Language · Computer Science 2024-10-21 Qi Cheng , Mert İnan , Rahma Mbarki , Grace Grmek , Theresa Choi , Yiming Sun , Kimele Persaud , Jenny Wang , Malihe Alikhani

Multimodal learning systems often face substantial uncertainty due to noisy data, low-quality labels, and heterogeneous modality characteristics. These issues become especially critical in human-computer interaction settings, where data…

Artificial Intelligence · Computer Science 2025-11-21 Hyo-Jeong Jang

Accurate survival prediction in Non-Small Cell Lung Cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal Deep Learning (MDL) can improve precision prognosis, but small cohorts and missing…

Medical data poses a daunting challenge for AI algorithms: it exists in many different modalities, experiences frequent distribution shifts, and suffers from a scarcity of examples and labels. Recent advances, including transformers and…