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Vision-Language Models (VLMs) offer significant potential in computational pathology by enabling interpretable image analysis, automated reporting, and scalable decision support. However, their widespread clinical adoption remains limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Minbing Chen , Zhu Meng , Fei Su

Recent advances in reasoning-enhanced large language models (LLMs) and multimodal LLMs (MLLMs) have significantly improved performance in complex tasks, yet medical AI models often overlook the structured reasoning processes inherent in…

Artificial Intelligence · Computer Science 2025-05-22 Ziqing Fan , Cheng Liang , Chaoyi Wu , Ya Zhang , Yanfeng Wang , Weidi Xie

Medical AI systems face two fundamental limitations. First, conventional vision-language models (VLMs) perform single-pass inference, yielding black-box predictions that cannot be audited or explained in clinical terms. Second, iterative…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Nicanor Mayumu , Zeenath Khan , Melodena Stephens , Patrick Mukala , Farhad Oroumchian

Vision-language models (VLMs) have shown strong promise for medical image analysis, but most remain opaque, offering predictions without the transparent, stepwise reasoning clinicians rely on. We present a framework that brings…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Andriy Myronenko , Dong Yang , Baris Turkbey , Mariam Aboian , Sena Azamat , Esra Akcicek , Hongxu Yin , Pavlo Molchanov , Marc Edgar , Yufan He , Pengfei Guo , Yucheng Tang , Daguang Xu

Vision Language Models (VLMs) like CLIP have attracted substantial attention in pathology, serving as backbones for applications such as zero-shot image classification and Whole Slide Image (WSI) analysis. Additionally, they can function as…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Yuxuan Sun , Yunlong Zhang , Yixuan Si , Chenglu Zhu , Zhongyi Shui , Kai Zhang , Jingxiong Li , Xingheng Lyu , Tao Lin , Lin Yang

Whole Slide Images (WSIs) exhibit hierarchical structure, where diagnostic information emerges from cellular morphology, regional tissue organization, and global context. Existing Computational Pathology (CPath) Multimodal Large Language…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Basit Alawode , Arif Mahmood , Muaz Khalifa Al-Radi , Shahad Albastaki , Asim Khan , Muhammad Bilal , Moshira Ali Abdalla , Mohammed Bennamoun , Sajid Javed

While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Fengchun Liu , Songhan Jiang , Linghan Cai , Ziyue Wang , Yongbing Zhang

Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face…

Large vision-language models (VLMs) for autonomous driving (AD) are evolving beyond perception and cognition tasks toward motion planning. However, we identify two critical challenges in this direction: (1) VLMs tend to learn shortcuts by…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Yue Li , Meng Tian , Dechang Zhu , Jiangtong Zhu , Zhenyu Lin , Zhiwei Xiong , Xinhai Zhao

Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu

Large vision-language models exhibit inherent capabilities to handle diverse visual perception tasks. In this paper, we introduce VisionReasoner, a unified framework capable of reasoning and solving multiple visual perception tasks within a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yuqi Liu , Tianyuan Qu , Zhisheng Zhong , Bohao Peng , Shu Liu , Bei Yu , Jiaya Jia

Interpretability is significant in computational pathology, leading to the development of multimodal information integration from histopathological image and corresponding text data.However, existing multimodal methods have limited…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Kangcheng Zhou , Jun Jiang , Qing Zhang , Shuang Zheng , Qingli Li , Shugong Xu

Topology is critical in tubular structures such as blood vessels, nerve fibers, and road networks, where connectivity and loop structure govern downstream functional analysis. Vision-Language Models (VLMs) are promising candidates for…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Meilong Xu , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Xin Yu , Weimin Lyu , Kehan Qi , Dimitris Samaras , Chao Chen

Chain-of-thought reasoning has significantly improved the performance of Large Language Models (LLMs) across various domains. However, this reasoning process has been confined exclusively to textual space, limiting its effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Haozhe Wang , Alex Su , Weiming Ren , Fangzhen Lin , Wenhu Chen

Computational pathology has advanced rapidly in recent years, driven by domain-specific image encoders and growing interest in using vision-language models to answer natural-language questions about diseases. Yet, the core problem behind…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Wentao Huang , Weimin Lyu , Peiliang Lou , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Wenchao Han , Ruifeng Guo , Jiawei Zhou , Chao Chen , Chen Wang

Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

Large language models (LLMs) have demonstrated remarkable advances in reasoning capabilities. However, their performance remains constrained by limited access to explicit and structured domain knowledge. Retrieval-Augmented Generation (RAG)…

Computation and Language · Computer Science 2025-10-20 Junlin Wu , Xianrui Zhong , Jiashuo Sun , Bolian Li , Bowen Jin , Jiawei Han , Qingkai Zeng

Large vision-language models (VLMs) have garnered increasing interest in autonomous driving areas, due to their advanced capabilities in complex reasoning tasks essential for highly autonomous vehicle behavior. Despite their potential,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Ming Nie , Renyuan Peng , Chunwei Wang , Xinyue Cai , Jianhua Han , Hang Xu , Li Zhang

Chain-of-thought has been proven essential for enhancing the complex reasoning abilities of Large Language Models (LLMs), but it also leads to high computational costs. Recent advances have explored the method to route queries among…

Computation and Language · Computer Science 2025-12-05 Chenyang Shao , Xinyang Liu , Yutang Lin , Fengli Xu , Yong Li

Large Multimodal Models (LMMs) have recently demonstrated remarkable visual understanding performance on both vision-language and vision-centric tasks. However, they often fall short in integrating advanced, task-specific capabilities for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Yufei Zhan , Hongyin Zhao , Yousong Zhu , Shurong Zheng , Fan Yang , Ming Tang , Jinqiao Wang