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The advancement of natural language processing (NLP) systems in healthcare hinges on language model ability to interpret the intricate information contained within clinical notes. This process often requires integrating information from…

Computation and Language · Computer Science 2024-03-12 Zhichao Yang , Avijit Mitra , Sunjae Kwon , Hong Yu

Language models (LMs), including large language models (such as ChatGPT), have the potential to assist clinicians in generating various clinical notes. However, LMs are prone to produce ``hallucinations'', i.e., generated content that is…

Computation and Language · Computer Science 2024-07-23 Fenglin Liu , Bang Yang , Chenyu You , Xian Wu , Shen Ge , Zhangdaihong Liu , Xu Sun , Yang Yang , David A. Clifton

Extracting structured information from clinical notes requires navigating a dense web of interdependent variables where the value of one attribute logically constrains others. Existing Large Language Model (LLM)-based extraction pipelines…

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

Electronic Health Records (EHRs) often lack explicit links between medications and diagnoses, making clinical decision-making and research more difficult. Even when links exist, diagnosis lists may be incomplete, especially during early…

Computation and Language · Computer Science 2025-03-31 Dina Albassam , Adam Cross , Chengxiang Zhai

Medical consultations are intrinsically speech-centric. However, most prior works focus on long-text-based interactions, which are cumbersome and patient-unfriendly. Recent advances in speech language models (SpeechLMs) have enabled more…

Computation and Language · Computer Science 2026-04-21 Sirry Chen , Jieyi Wang , Wei Chen , Zhongyu Wei

The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

Computation and Language · Computer Science 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

Large language models (LLMs) can generate or synthesize clinical text for a wide range of applications, from improving clinical documentation to augmenting clinical text analytics. Yet evaluations typically focus on a narrow aspect -- such…

Computation and Language · Computer Science 2026-05-19 Jinghui Liu , Sarvesh Soni , Anthony Nguyen

Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

Clinical notes are a rich source of information about patient state. However, using them to predict clinical events with machine learning models is challenging. They are very high dimensional, sparse and have complex structure. Furthermore,…

Machine Learning · Statistics 2018-08-20 Sebastien Dubois , Nathanael Romano , David C. Kale , Nigam Shah , Kenneth Jung

Large language models (LLMs) achieve high accuracy in medical diagnosis when all clinical information is provided in a single turn, yet how they behave under multi-turn evidence accumulation closer to real clinical reasoning remains…

Computation and Language · Computer Science 2026-04-07 Jinrui Fang , Runhan Chen , Xu Yang , Jian Yu , Jiawei Xu , Ashwin Vinod , Wenqi Shi , Tianlong Chen , Heng Ji , ChengXiang Zhai , Ying Ding , Yuji Zhang

A decade of rapid advances in artificial intelligence (AI) has opened new opportunities for clinical decision support systems (CDSS), with large language models (LLMs) demonstrating strong reasoning abilities on timely medical tasks.…

Computation and Language · Computer Science 2025-11-25 Heejoon Koo

Both medical care and observational studies in oncology require a thorough understanding of a patient's disease progression and treatment history, often elaborately documented in clinical notes. Despite their vital role, no current oncology…

Computation and Language · Computer Science 2024-03-18 Madhumita Sushil , Vanessa E. Kennedy , Divneet Mandair , Brenda Y. Miao , Travis Zack , Atul J. Butte

We propose DISC-MedLLM, a comprehensive solution that leverages Large Language Models (LLMs) to provide accurate and truthful medical response in end-to-end conversational healthcare services. To construct high-quality Supervised…

Computation and Language · Computer Science 2023-08-29 Zhijie Bao , Wei Chen , Shengze Xiao , Kuang Ren , Jiaao Wu , Cheng Zhong , Jiajie Peng , Xuanjing Huang , Zhongyu Wei

Clinician notes are a rich source of patient information but often contain inconsistencies due to varied writing styles, colloquialisms, abbreviations, medical jargon, grammatical errors, and non-standard formatting. These inconsistencies…

Computation and Language · Computer Science 2025-01-03 Daniel B. Hier , Michael D. Carrithers , Thanh Son Do , Tayo Obafemi-Ajayi

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Large language models are being rapidly deployed across many fields such as healthcare, finance, transportation, and energy, where time-series data are fundamental components. The current works are still limited in their ability to perform…

Artificial Intelligence · Computer Science 2026-01-23 Paul Quinlan , Qingguo Li , Xiaodan Zhu

With the rapid advancement of Large Language Models (LLMs) and their outstanding performance in semantic and contextual comprehension, the potential of LLMs in specialized domains warrants exploration. This paper introduces the NoteAid EHR…

Computation and Language · Computer Science 2024-01-01 Xiaocheng Zhang , Zonghai Yao , Hong Yu

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

Clinical language models are important for many applications in healthcare, but their development depends on access to extensive clinical text for pretraining. However, obtaining clinical notes from electronic health records (EHRs) at scale…

Computation and Language · Computer Science 2024-12-02 Jinghui Liu , Anthony Nguyen