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Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

Artificial Intelligence · Computer Science 2025-01-27 Arjun R. Malghan

Despite advances in machine learning (ML) and large language models (LLMs), rule-based natural language processing (NLP) systems remain active in clinical settings due to their interpretability and operational efficiency. However, their…

Computation and Language · Computer Science 2025-06-23 Jianlin Shi , Brian T. Bucher

Current medical AI systems often fail to replicate real-world clinical reasoning, as they are predominantly trained and evaluated on static text and question-answer tasks. These tuning methods and benchmarks overlook critical aspects like…

Computation and Language · Computer Science 2026-02-24 Zijie Liu , Xinyu Zhao , Jie Peng , Zhuangdi Zhu , Qingyu Chen , Kaidi Xu , Xia Hu , Tianlong Chen

Participant recruitment based on unstructured medical texts such as clinical notes and radiology reports has been a challenging yet important task for the cohort establishment in clinical research. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2023-07-24 Zihan Guan , Zihao Wu , Zhengliang Liu , Dufan Wu , Hui Ren , Quanzheng Li , Xiang Li , Ninghao Liu

Multimodal large language models (MLLMs), built on large-scale pre-trained vision towers and language models, have shown great capabilities in multimodal understanding. However, most existing MLLMs are trained on single-turn vision…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Jiazheng Liu , Sipeng Zheng , Börje F. Karlsson , Zongqing Lu

Large Language Models (LLMs) are increasingly employed in multi-turn conversational tasks, yet their pre-training data predominantly consists of continuous prose, creating a potential mismatch between required capabilities and training…

Computation and Language · Computer Science 2025-07-09 Jing Yang Lee , Hamed Bonab , Nasser Zalmout , Ming Zeng , Sanket Lokegaonkar , Colin Lockard , Binxuan Huang , Ritesh Sarkhel , Haodong Wang

Large Language Models (LLMs) are increasingly deployed in medicine. However, their utility in non-generative clinical prediction, often presumed inferior to specialized models, remains under-evaluated, leading to ongoing debate within the…

Clinical conversation summarization has become an important application of Natural language Processing. In this work, we intend to analyze summarization model ensembling approaches, that can be utilized to improve the overall accuracy of…

Computation and Language · Computer Science 2023-06-08 Dhananjay Srivastava

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

A growing body of work uses Natural Language Processing (NLP) methods to automatically generate medical notes from audio recordings of doctor-patient consultations. However, there are very few studies on how such systems could be used in…

The work in this paper evaluates zero-shot and few-shot large language models (LLMs) for safety-critical clinical action extraction using the CLIP discharge-note dataset, with particular emphasis on transitions of care and post-discharge…

Artificial Intelligence · Computer Science 2026-05-08 Shivali Dalmia , Ananya Mantravadi , Prasanna Desikan

Electronic health records (EHRs) house crucial patient data in clinical notes. As these notes grow in volume and complexity, manual extraction becomes challenging. This work introduces a natural language interface using large language…

Information Retrieval · Computer Science 2024-07-03 Ran Elgedawy , Ioana Danciu , Maria Mahbub , Sudarshan Srinivasan

Large language models (LLMs) hold great promise for assisting clinical interviews due to their fluent interactive capabilities and extensive medical knowledge. However, the lack of high-quality interview dialogue data and widely accepted…

Computation and Language · Computer Science 2025-04-15 Jing Chen , Zhihua Wei , Wei Zhang , Yingying Hu , Qiong Zhang

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

Proprietary Large Language Models (LLMs) such as GPT-4 and Gemini have demonstrated promising capabilities in clinical text summarization tasks. However, due to patient data privacy concerns and computational costs, many healthcare…

Extracting sections from clinical notes is crucial for downstream analysis but is challenging due to variability in formatting and labor-intensive nature of manual sectioning. While proprietary large language models (LLMs) have shown…

Computation and Language · Computer Science 2025-01-27 Joshua Davis , Thomas Sounack , Kate Sciacca , Jessie M Brain , Brigitte N Durieux , Nicole D Agaronnik , Charlotta Lindvall

OpenNotes enables patients to access EHR notes, but medical jargon can hinder comprehension. To improve understanding, we evaluated closed- and open-source LLMs for extracting and prioritizing key medical terms using prompting, fine-tuning,…

Computation and Language · Computer Science 2026-05-08 Won Seok Jang , Sharmin Sultana , Zonghai Yao , Hieu Tran , Zhichao Yang , Sunjae Kwon , Hong Yu

Despite the impressive capabilities of Large Language Models (LLMs), existing Conversational Health Agents (CHAs) remain static and brittle, incapable of adaptive multi-turn reasoning, symptom clarification, or transparent decision-making.…

Computation and Language · Computer Science 2025-07-11 Xinyi Liu , Dachun Sun , Yi R. Fung , Dilek Hakkani-Tür , Tarek Abdelzaher

Iterative RAG for multi-hop question answering faces challenges with lengthy contexts and the buildup of irrelevant information. This hinders a model's capacity to process and reason over retrieved content and limits performance. While…

In the past decade a surge in the amount of electronic health record (EHR) data in the United States, attributed to a favorable policy environment created by the Health Information Technology for Economic and Clinical Health (HITECH) Act of…

Computation and Language · Computer Science 2025-12-08 Ivan Makohon , Mohamad Najafi , Jian Wu , Mathias Brochhausen , Yaohang Li