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Survival analysis using whole-slide images (WSIs) is crucial in cancer research. Despite significant successes, pathology images typically only provide slide-level labels, which hinders the learning of discriminative representations from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Chengsheng Zhang , Linhao Qu , Xiaoyu Liu , Zhijian Song

Multimodal pathology-genomic analysis is critical for cancer survival prediction. However, existing approaches predominantly integrate formalin-fixed paraffin-embedded (FFPE) slides with genomic data, while neglecting the availability of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Mingcheng Qu , Guang Yang , Donglin Di , Yue Gao , Tonghua Su , Yang Song , Lei Fan

Accurate survival prediction in Non-Small Cell Lung Cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal Deep Learning (MDL) can improve precision prognosis, but small cohorts and missing…

Survival prediction, utilizing pathological images and genomic profiles, is increasingly important in cancer analysis and prognosis. Despite significant progress, precise survival analysis still faces two main challenges: (1) The massive…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Songhan Jiang , Zhengyu Gan , Linghan Cai , Yifeng Wang , Yongbing Zhang

Multi-modality image fusion (MMIF) aims to integrate complementary information from different modalities into a single fused image to represent the imaging scene and facilitate downstream visual tasks comprehensively. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Zhe Li , Haiwei Pan , Kejia Zhang , Yuhua Wang , Fengming Yu

Cancer survival prediction from whole slide images (WSIs) is a challenging task in computational pathology due to the large size, irregular shape, and high granularity of the WSIs. These characteristics make it difficult to capture the full…

Image and Video Processing · Electrical Eng. & Systems 2025-03-05 Rustin Soraki , Huayu Wang , Joann G. Elmore , Linda Shapiro

The rapidly emerging field of deep learning-based computational pathology has shown promising results in utilizing whole slide images (WSIs) to objectively prognosticate cancer patients. However, most prognostic methods are currently…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Mingxin Liu , Yunzan Liu , Hui Cui , Chunquan Li , Jiquan Ma

Whole slide image (WSI) analysis has emerged as an increasingly essential technique in computational pathology. Recent advances in the pathology foundation models (FMs) have demonstrated significant advantages in deriving meaningful…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Zhidong Yang , Xiuhui Shi , Wei Ba , Zhigang Song , Haijing Luan , Taiyuan Hu , Senlin Lin , Jiguang Wang , Shaohua Kevin Zhou , Rui Yan

Multi-modal medical image fusion (MMIF) is increasingly recognized as an essential technique for enhancing diagnostic precision and facilitating effective clinical decision-making within computer-aided diagnosis systems. MMIF combines data…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Muhammad Zubair , Muzammil Hussai , Mousa Ahmad Al-Bashrawi , Malika Bendechache , Muhammad Owais

Learning from multimodal datasets can leverage complementary information and improve performance in prediction tasks. A commonly used strategy to account for feature correlations in high-dimensional datasets is the latent variable approach.…

Machine Learning · Computer Science 2024-10-01 Lingchao Mao , Qi wang , Yi Su , Fleming Lure , Jing Li

Image fusion integrates complementary information from different modalities to generate high-quality fused images, thereby enhancing downstream tasks such as object detection and semantic segmentation. Unlike task-specific techniques that…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Yingying Wang , Rongjin Zhuang , Hui Zheng , Xuanhua He , Ke Cao , Xiaotong Tu , Xinghao Ding

Multi-modal MRI offers valuable complementary information for diagnosis and treatment; however, its utility is limited by prolonged scanning times. To accelerate the acquisition process, a practical approach is to reconstruct images of the…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Jing Zou , Lanqing Liu , Qi Chen , Shujun Wang , Zhanli Hu , Xiaohan Xing , Jing Qin

Accurate cancer survival prediction is crucial for assisting clinical doctors in formulating treatment plans. Multimodal data, including histopathological images and genomic data, offer complementary and comprehensive information that can…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Hui Luo , Jiashuang Huang , Hengrong Ju , Tianyi Zhou , Weiping Ding

Survival prediction is a crucial task in the medical field and is essential for optimizing treatment options and resource allocation. However, current methods often rely on limited data modalities, resulting in suboptimal performance. In…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Binyu Zhang , Zhu Meng , Junhao Dong , Fei Su , Zhicheng Zhao

Learning good representation of giga-pixel level whole slide pathology images (WSI) for downstream tasks is critical. Previous studies employ multiple instance learning (MIL) to represent WSIs as bags of sampled patches because, for most…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Chunyuan Li , Xinliang Zhu , Jiawen Yao , Junzhou Huang

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

We propose a modular framework for predicting cancer specific survival directly from whole slide pathology images (WSIs). The framework consists of four key stages designed to capture prognostic and morphological heterogeneity. First, a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Garima Jain , Pranav Jeevan , Amit Sethi

Multi-modality image fusion (MMIF) combines complementary information from different image modalities to provide a comprehensive and objective interpretation of scenes. However, existing fusion methods cannot resist different weather…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Xilai Li , Wuyang Liu , Xiaosong Li , Fuqiang Zhou , Huafeng Li , Feiping Nie

Multi-Modal Image Fusion (MMIF) aims to integrate complementary image information from different modalities to produce informative images. Previous deep learning-based MMIF methods generally adopt Convolutional Neural Networks (CNNs) or…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Hui Sun , Long Lv , Pingping Zhang , Tongdan Tang , Feng Tian , Weibing Sun , Huchuan Lu

Effective understanding of a disease such as cancer requires fusing multiple sources of information captured across physical scales by multimodal data. In this work, we propose a novel feature embedding module that derives from canonical…

Machine Learning · Computer Science 2021-03-10 Vaishnavi Subramanian , Tanveer Syeda-Mahmood , Minh N. Do
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