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Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Multi-modal image fusion (MMIF) integrates valuable information from different modality images into a fused one. However, the fusion of multiple visible images with different focal regions and infrared images is a unprecedented challenge in…

Computer Vision and Pattern Recognition · Computer Science 2024-02-01 Xilai Li , Xiaosong Li , Tao Ye , Xiaoqi Cheng , Wuyang Liu , Haishu Tan

Multimodal image fusion (MMIF) integrates information from different modalities to obtain a comprehensive image, aiding downstream tasks. However, existing research focuses on complementary information fusion and training strategies,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Dan He , Guofen Wang , Weisheng Li , Yucheng Shu , Wenbo Li , Lijian Yang , Yuping Huang , Feiyan Li

Glioblastoma is a highly invasive brain tumor with rapid progression rates. Recent studies have shown that glioblastoma molecular subtype classification serves as a significant biomarker for effective targeted therapy selection. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Shekhnaz Idrissova , Islem Rekik

Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Machine Learning · Computer Science 2025-02-04 Jie Peng , Shuang Zhou , Longwei Yang , Yiran Song , Mohan Zhang , Kaixiong Zhou , Feng Xie , Mingquan Lin , Rui Zhang , Tianlong Chen

Whole slide image (WSI) refers to a type of high-resolution scanned tissue image, which is extensively employed in computer-assisted diagnosis (CAD). The extremely high resolution and limited availability of region-level annotations make…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Ruijie Zhang , Qiaozhe Zhang , Yingzhuang Liu , Hao Xin , Yan Liu , Xinggang Wang

In the field of multimodal medical data analysis, leveraging diverse types of data and understanding their hidden relationships continues to be a research focus. The main challenges lie in effectively modeling the complex interactions…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Xuhao Shan , Ruiquan Ge , Jikui Liu , Linglong Wu , Chi Zhang , Siqi Liu , Wenjian Qin , Wenwen Min , Ahmed Elazab , Changmiao Wang

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Recently, pathological diagnosis has achieved superior performance by combining deep learning models with the multiple instance learning (MIL) framework using whole slide images (WSIs). However, the giga-pixeled nature of WSIs poses a great…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Zijie Fang , Yifeng Wang , Ye Zhang , Zhi Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Multi-modal entity alignment (MMEA) is essential for enhancing knowledge graphs and improving information retrieval and question-answering systems. Existing methods often focus on integrating modalities through their complementarity but…

Artificial Intelligence · Computer Science 2024-10-21 Wei Ai , Wen Deng , Hongyi Chen , Jiayi Du , Tao Meng , Yuntao Shou

Multimodal learning mimics the reasoning process of the human multi-sensory system, which is used to perceive the surrounding world. While making a prediction, the human brain tends to relate crucial cues from multiple sources of…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Lang Su , Chuqing Hu , Guofa Li , Dongpu Cao

Multimodal survival methods combining gigapixel histology whole-slide images (WSIs) and transcriptomic profiles are particularly promising for patient prognostication and stratification. Current approaches involve tokenizing the WSIs into…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Andrew H. Song , Richard J. Chen , Guillaume Jaume , Anurag J. Vaidya , Alexander S. Baras , Faisal Mahmood

Existing brain tumor segmentation methods usually utilize multiple Magnetic Resonance Imaging (MRI) modalities in brain tumor images for segmentation, which can achieve better segmentation performance. However, in clinical applications,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Ming Kang , Fung Fung Ting , Shier Nee Saw , Raphaël C. -W. Phan , Zongyuan Ge , Chee-Ming Ting

Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Ting Jin , Xingran Xie , Renjie Wan , Qingli Li , Yan Wang

Multimodal fusion has made great progress in the field of remote sensing image classification due to its ability to exploit the complementary spatial-spectral information. Deep learning methods such as CNN and Transformer have been widely…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Qingyu Wang , Xue Jiang , Guozheng Xu

Accurate survival prediction in oncology requires integrating diverse imaging modalities to capture the complex interplay of tumor biology. Traditional single-modality approaches often fail to leverage the complementary insights provided by…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Ho Hin Lee , Alberto Santamaria-Pang , Jameson Merkov , Matthew Lungren , Ivan Tarapov

Neuroimaging techniques including functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) have shown promise in detecting functional abnormalities in various brain disorders. However, existing studies often focus on a…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Xinxu Wei , Kanhao Zhao , Yong Jiao , Nancy B. Carlisle , Hua Xie , Gregory A. Fonzo , Yu Zhang

Multimodal Sentiment Analysis (MSA) leverages multiple data modals to analyze human sentiment. Existing MSA models generally employ cutting-edge multimodal fusion and representation learning-based methods to promote MSA capability. However,…

Computation and Language · Computer Science 2024-12-04 Yijie Jin

Addressing the challenge of multimodal data fusion in high-dimensional biomedical informatics, we propose MMCTOP, a MultiModal Clinical-Trial Outcome Prediction framework that integrates heterogeneous biomedical signals spanning (i)…

Machine Learning · Computer Science 2025-12-29 Carolina Aparício , Qi Shi , Bo Wen , Tesfaye Yadete , Qiwei Han