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Head and neck tumors and metastatic lymph nodes are crucial for treatment planning and prognostic analysis. Accurate segmentation and quantitative analysis of these structures require pixel-level annotation, making automated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 Litingyu Wang , Wenjun Liao , Shichuan Zhang , Guotai Wang

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

Several machine learning techniques for accurate detection of skin cancer from medical images have been reported. Many of these techniques are based on pre-trained convolutional neural networks (CNNs), which enable training the models based…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Aqsa Saeed Qureshi , Teemu Roos

Whole Slide Images (WSIs) provide exceptional detail for studying tissue architecture at the cell level. To study tumour microenvironment (TME) with the context of various protein biomarkers and cell sub-types, analysis and registration of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Adith Jeyasangar , Abdullah Alsalemi , Shan E Ahmed Raza

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

Semantic segmentation of electron microscopy (EM) is an essential step to efficiently obtain reliable morphological statistics. Despite the great success achieved using deep convolutional neural networks (CNNs), they still produce coarse…

Computer Vision and Pattern Recognition · Computer Science 2021-01-11 Zhimin Yuan , Xiaofen Ma , Jiajin Yi , Zhengrong Luo , Jialin Peng

Nuclei instance segmentation in histopathological images is of great importance for biological analysis and cancer diagnosis but remains challenging for two reasons. (1) Similar visual presentation of intranuclear and extranuclear regions…

Computer Vision and Pattern Recognition · Computer Science 2024-02-12 Ye Zhang , Linghan Cai , Ziyue Wang , Yongbing Zhang

Deep learning methods have been widely used for Human Activity Recognition (HAR) using recorded signals from Iner-tial Measurement Units (IMUs) sensors that are installed on various parts of the human body. For this type of HAR, sev-eral…

Machine Learning · Computer Science 2025-02-10 Saeed Arabzadeh , Farshad Almasganj , Mohammad Mahdi Ahmadi

Deep learning has gained significant attention in medical image segmentation. However, the limited availability of annotated training data presents a challenge to achieving accurate results. In efforts to overcome this challenge, data…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome. To drive innovation in this area, we setup a community-wide challenge using…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Simon Graham , Quoc Dang Vu , Mostafa Jahanifar , Martin Weigert , Uwe Schmidt , Wenhua Zhang , Jun Zhang , Sen Yang , Jinxi Xiang , Xiyue Wang , Josef Lorenz Rumberger , Elias Baumann , Peter Hirsch , Lihao Liu , Chenyang Hong , Angelica I. Aviles-Rivero , Ayushi Jain , Heeyoung Ahn , Yiyu Hong , Hussam Azzuni , Min Xu , Mohammad Yaqub , Marie-Claire Blache , Benoît Piégu , Bertrand Vernay , Tim Scherr , Moritz Böhland , Katharina Löffler , Jiachen Li , Weiqin Ying , Chixin Wang , Dagmar Kainmueller , Carola-Bibiane Schönlieb , Shuolin Liu , Dhairya Talsania , Yughender Meda , Prakash Mishra , Muhammad Ridzuan , Oliver Neumann , Marcel P. Schilling , Markus Reischl , Ralf Mikut , Banban Huang , Hsiang-Chin Chien , Ching-Ping Wang , Chia-Yen Lee , Hong-Kun Lin , Zaiyi Liu , Xipeng Pan , Chu Han , Jijun Cheng , Muhammad Dawood , Srijay Deshpande , Raja Muhammad Saad Bashir , Adam Shephard , Pedro Costa , João D. Nunes , Aurélio Campilho , Jaime S. Cardoso , Hrishikesh P S , Densen Puthussery , Devika R G , Jiji C , Ye Zhang , Zijie Fang , Zhifan Lin , Yongbing Zhang , Chunhui Lin , Liukun Zhang , Lijian Mao , Min Wu , Vi Thi-Tuong Vo , Soo-Hyung Kim , Taebum Lee , Satoshi Kondo , Satoshi Kasai , Pranay Dumbhare , Vedant Phuse , Yash Dubey , Ankush Jamthikar , Trinh Thi Le Vuong , Jin Tae Kwak , Dorsa Ziaei , Hyun Jung , Tianyi Miao , David Snead , Shan E Ahmed Raza , Fayyaz Minhas , Nasir M. Rajpoot

In digital pathology, segmenting densely distributed objects like glands and nuclei is crucial for downstream analysis. Since detailed pixel-wise annotations are very time-consuming, we need semi-supervised segmentation methods that can…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 Meilong Xu , Xiaoling Hu , Saumya Gupta , Shahira Abousamra , Chao Chen

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

To accurately analyze changes of anatomical structures in longitudinal imaging studies, consistent segmentation across multiple time-points is required. Existing solutions often involve independent registration and segmentation components.…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Bo Li , Wiro Niessen , Stefan Klein , Marius de Groot , Arfan Ikram , Meike Vernooij , Esther Bron

Image segmentation is a critical step in computational biomedical image analysis, typically evaluated using metrics like the Dice coefficient during training and validation. However, in clinical settings without manual annotations,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Sikha O K , Meritxell Riera-Marín , Adrian Galdran , Javier García Lopez , Julia Rodríguez-Comas , Gemma Piella , Miguel A. González Ballester

Nuclei segmentation, despite its fundamental role in histopathological image analysis, is still a challenge work. The main challenge of this task is the existence of overlapping areas, which makes separating independent nuclei more…

Image and Video Processing · Electrical Eng. & Systems 2024-07-25 Dinh-Phu Tran , Quoc-Anh Nguyen , Van-Truong Pham , Thi-Thao Tran

Computational pathology has made significant progress in recent years, fueling advances in both fundamental disease understanding and clinically ready tools. This evolution is driven by the availability of large amounts of digitized slides…

Automated classification of histopathological whole-slide images (WSI) of breast tissue requires analysis at very high resolutions with a large contextual area. In this paper, we present context-aware stacked convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2017-05-11 Babak Ehteshami Bejnordi , Guido Zuidhof , Maschenka Balkenhol , Meyke Hermsen , Peter Bult , Bram van Ginneken , Nico Karssemeijer , Geert Litjens , Jeroen van der Laak

Current state-of-the-art medical image segmentation methods prioritize accuracy but often at the expense of increased computational demands and larger model sizes. Applying these large-scale models to the relatively limited scale of medical…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Jiahui Zhong , Wenhong Tian , Yuanlun Xie , Zhijia Liu , Jie Ou , Taoran Tian , Lei Zhang

Medical image segmentation assists in computer-aided diagnosis, surgeries, and treatment. Digitize tissue slide images are used to analyze and segment glands, nuclei, and other biomarkers which are further used in computer-aided medical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-05 Saad Wazir , Muhammad Moazam Fraz

Accurate detection of oral cancer is crucial for improving patient outcomes. However, the field faces two key challenges: the scarcity of deep learning-based image segmentation research specifically targeting oral cancer and the lack of…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Ahmed Albishri , Syed Jawad Hussain Shah , Yugyung Lee , Rong Wang