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Background: Pleural Effusions (PE) is a common finding in many different clinical conditions, but accurately measuring their volume from CT scans is challenging. Purpose: To improve PE segmentation and quantification for enhanced clinical…
Ultrasound (US) imaging is widely used in diagnosing and staging abdominal diseases due to its lack of non-ionizing radiation and prevalent availability. However, significant inter-operator variability and inconsistent image acquisition…
Eosinophilic esophagitis (EoE) is a chronic esophageal disorder marked by eosinophil-dominated inflammation. Diagnosing EoE usually involves endoscopic inspection of the esophageal mucosa and obtaining esophageal biopsies for histologic…
Neural circuit reconstruction at single synapse resolution is increasingly recognized as crucially important to decipher the function of biological nervous systems. Volume electron microscopy in serial transmission or scanning mode has been…
High quality structural volumetric imaging is a challenging goal to achieve with modern ultrasound transducers. Matrix probes have limited fields of view and element counts, whereas row-column arrays (RCAs) provide insufficient focusing. In…
Identification of vessel structures of different sizes in biomedical images is crucial in the diagnosis of many neurodegenerative diseases. However, the sparsity of good-quality annotations of such images makes the task of vessel…
Despite the growing availability of Electronic Health Record (EHR) data, researchers often face substantial barriers in effectively using these data for translational research due to their complexity, heterogeneity, and lack of standardized…
Objectives: Precise segmentation of total extraocular muscles (EOM) and optic nerve (ON) is essential to assess anatomical development and progression of thyroid-associated ophthalmopathy (TAO). We aim to develop a semantic segmentation…
Deep learning has enabled great strides in abdominal multi-organ segmentation, even surpassing junior oncologists on common cases or organs. However, robustness on corner cases and complex organs remains a challenging open problem for…
Purpose: Subglottic stenosis refers to the narrowing of the subglottis, the airway between the vocal cords and the trachea. Its severity is typically evaluated by estimating the percentage of obstructed airway. This estimation can be…
Traditional classifiers treat all labels as mutually independent, thereby considering all negative classes to be equally incorrect. This approach fails severely in many real-world scenarios, where a known semantic hierarchy defines a…
Osteoarthritis is a degenerative condition affecting bones and cartilage, often leading to osteophyte formation, bone density loss, and joint space narrowing. Treatment options to restore normal joint function vary depending on the severity…
Endoscopic depth estimation is a critical technology for improving the safety and precision of minimally invasive surgery. It has attracted considerable attention from researchers in medical imaging, computer vision, and robotics. Over the…
Magnetorheological fluids (MR) are stable suspensions of magnetizable microparticles, characterized by the property to change the rheological characteristics when subjected to the action of magnetic field. Together with another class of…
With the emergence of swept-volume ultrasound (US) probes, precise and almost real-time US volume imaging has become available. This offers many new opportunities for computer guided diagnosis and therapy, 3-D images containing…
Clinical imaging is routinely used for cochlear implant surgical planning yet lacks the resolution and contrast necessary to visualize the fine intracochlear structures critical for individualized intervention. To address this limitation,…
Nowadays, cardiac diagnosis largely depends on left ventricular function assessment. With the help of the segmentation deep learning model, the assessment of the left ventricle becomes more accessible and accurate. However, deep learning…
In endoscopic sinus surgery (ESS), intraoperative CT (iCT) offers valuable intraoperative assessment but is constrained by slow deployment and radiation exposure, limiting its clinical utility. Endoscope-based monocular 3D reconstruction is…
Medical ultrasound (US) imaging is a frontline tool for the diagnosis of kidney diseases. However, traditional freehand imaging procedure suffers from inconsistent, operator-dependent outcomes, lack of 3D localization information, and risks…
Reconstructing a synaptic wiring diagram, or connectome, from electron microscopy (EM) images of brain tissue currently requires many hours of manual annotation or proofreading (Kasthuri and Lichtman, 2010; Lichtman and Sanes, 2008; Seung,…