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Molecular computation based on chemical reaction networks (CRNs) has emerged as a promising paradigm for designing programmable biochemical systems. However, the implementation of complex computations still requires excessively large and…

Molecular Networks · Quantitative Biology 2025-06-17 Renlei Jiang , Yuzhen Fan , Di Fan , Chuanhou Gao , Denis Dochain

Adoption of state-of-art Generative Artificial Intelligence (GenAI) aims to revolutionize many industrial areas by reducing the amount of human intervention needed and effort for handling complex underlying processes. Automotive software…

Layout designs are encountered in a variety of fields. For problems with many design degrees of freedom, efficiency of design methods becomes a major concern. In recent years, machine learning methods such as artificial neural networks have…

Machine Learning · Computer Science 2021-02-01 Chao Qian , Renkai Tan , Wenjing Ye

Predicting stochastic cellular dynamics as emerging from the mechanistic models of molecular interactions is a long-standing challenge in systems biology: low-level chemical reaction network (CRN) models give raise to a highly-dimensional…

Molecular Networks · Quantitative Biology 2020-02-06 Tatjana Petrov , Denis Repin

Semantic communication (SemCom) is expected to be a core paradigm in future communication networks, yielding significant benefits in terms of spectrum resource saving and information interaction efficiency. However, the existing SemCom…

Networking and Internet Architecture · Computer Science 2024-10-29 Le Xia , Yao Sun , Chengsi Liang , Lei Zhang , Muhammad Ali Imran , Dusit Niyato

Traditional artificial neural networks consist of nodes with non-oscillatory dynamics. Biological neural networks, on the other hand, consist of oscillatory components embedded in an oscillatory environment. Motivated by this feature of…

Neurons and Cognition · Quantitative Biology 2026-03-17 Mark A. Kramer

The rapid adoption of generative artificial intelligence (GenAI) in the biosciences is transforming biotechnology, medicine, and synthetic biology. Yet this advancement is intrinsically linked to new vulnerabilities, as GenAI lowers the…

Most existing swarm pattern formation methods depend on a predefined gene regulatory network (GRN) structure that requires designers' priori knowledge, which is difficult to adapt to complex and changeable environments. To dynamically adapt…

Neural and Evolutionary Computing · Computer Science 2019-11-04 Zhun Fan , Zhaojun Wang , Xiaomin Zhu , Bingliang Hu , Anmin Zou , Dongwei Bao

Our work is concerned with the generation and targeted design of RNA, a type of genetic macromolecule that can adopt complex structures which influence their cellular activities and functions. The design of large scale and complex…

Biomolecules · Quantitative Biology 2021-02-02 Zichao Yan , William L. Hamilton , Mathieu Blanchette

The rapid advance of generative AI is reshaping the strategic vision for R&D across industries. The unique challenges of pharmaceutical R&D will see applications of generative AI deliver value along the entire value chain from early…

Quantitative Methods · Quantitative Biology 2023-12-21 Guy Doron , Sam Genway , Mark Roberts , Sai Jasti

Gene regulatory networks (GRNs) orchestrate cellular decision making and survival strategies. Inferring the structure of these networks from high-dimensional transcriptomics data is a central challenge in systems biology. Traditional…

Applications · Statistics 2025-08-01 Visweswaran Ravikumar , Aaresh Bhathena , Wajd N Al-Holou , Salar Fattahi , Arvind Rao

Generative Artificial Intelligence (GenAI) presents a governance challenge for STEM assessment. Unrestricted GenAI access enables task outsourcing that undermines the validity of traditional assessments; blanket prohibitions are difficult…

Computers and Society · Computer Science 2026-05-26 Yizhu Gao , Zhongzhou Chen , Min Li , Xiaoming Zhai

Cognitive radio networks (CRNs) are networks of nodes equipped with cognitive radios that can optimize performance by adapting to network conditions. While cognitive radio networks (CRN) are envisioned as intelligent networks, relatively…

Networking and Internet Architecture · Computer Science 2015-11-06 Junaid Qadir

Modern machine learning techniques, such as deep neural networks, are transforming many disciplines ranging from image recognition to language understanding, by uncovering patterns in big data and making accurate predictions. They have also…

Machine Learning · Computer Science 2021-03-11 Amin Heyrani Nobari , Muhammad Fathy Rashad , Faez Ahmed

This paper explores the critical transition from Generative Artificial Intelligence (GenAI) to Innovative Artificial Intelligence (InAI). While recent advancements in GenAI have enabled systems to produce high-quality content across various…

Machine Learning · Computer Science 2025-03-17 Seyed Mahmoud Sajjadi Mohammadabadi

The idea of using deep-learning-based molecular generation to accelerate discovery of drug candidates has attracted extraordinary attention, and many deep generative models have been developed for automated drug design, termed molecular…

Biomolecules · Quantitative Biology 2024-05-01 Odin Zhang , Haitao Lin , Hui Zhang , Huifeng Zhao , Yufei Huang , Yuansheng Huang , Dejun Jiang , Chang-yu Hsieh , Peichen Pan , Tingjun Hou

Random graph models have been instrumental in characterizing complex networks, but chemical reaction networks (CRNs) are better represented as hypergraphs. Traditional models of random CRNs often reduce CRNs to bipartite graphs,…

Statistical Mechanics · Physics 2025-07-15 Shesha Gopal Marehalli Srinivas , Massimiliano Esposito , Nahuel Freitas

This paper presents a novel approach to advancing artificial intelligence (AI) through the development of the Complex Recurrent Spectral Network ($\mathbb{C}$-RSN), an innovative variant of the Recurrent Spectral Network (RSN) model. The…

Machine Learning · Computer Science 2023-12-13 Lorenzo Chicchi , Lorenzo Giambagli , Lorenzo Buffoni , Raffaele Marino , Duccio Fanelli

Chemical reaction networks (CRNs) are foundational models for describing complex biochemical processes. We study noncompetitive CRNs, a class of networks whose static states are rate-independent, and that can implement ReLU neural networks.…

Molecular Networks · Quantitative Biology 2025-12-22 Louis Faul , Xavier Richard , Mary Betrisey , Christian Mazza

Network neuroscience is the emerging discipline concerned with investigating the complex patterns of interconnections found in neural systems, and to identify principles with which to understand them. Within this discipline, one…

Neurons and Cognition · Quantitative Biology 2017-08-29 Richard F. Betzel , Danielle S. Bassett