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Modelling gene regulatory networks not only requires a thorough understanding of the biological system depicted but also the ability to accurately represent this system from a mathematical perspective. Throughout this chapter, we aim to…

Quantitative Methods · Quantitative Biology 2018-05-04 Olivia Angelin-Bonnet , Patrick J. Biggs , Matthieu Vignes

Unraveling the complexities of Gene Regulatory Networks (GRNs) is crucial for understanding cellular processes and disease mechanisms. Traditional computational methods often struggle with the dynamic nature of these networks. This study…

Machine Learning · Computer Science 2025-03-04 Hakan T. Otal , Abdulhamit Subasi , Furkan Kurt , M. Abdullah Canbaz , Yasin Uzun

Traditional Celluloid (Cel) Animation production pipeline encompasses multiple essential steps, including storyboarding, layout design, keyframe animation, inbetweening, and colorization, which demand substantial manual effort, technical…

In the contemporary big data realm, Deep Neural Networks (DNNs) are evolving towards more complex architectures to achieve higher inference accuracy. Model compression techniques can be leveraged to efficiently deploy such compute-intensive…

Machine Learning · Computer Science 2020-04-15 Mojan Javaheripi , Mohammad Samragh , Tara Javidi , Farinaz Koushanfar

Artificial Neural Networks (ANN) have been popularized in many science and technological areas due to their capacity to solve many complex pattern matching problems. That is the case of Virtual Screening, a research area that studies how to…

Neural and Evolutionary Computing · Computer Science 2020-06-05 Christian F. Frasser , Carola de Benito , Vincent Canals , Miquel Roca , Pedro J. Ballester , Josep L. Rossello

Generative artificial intelligence (GenAI) holds the potential to transform the delivery, cultivation, and evaluation of human learning. This Perspective examines the integration of GenAI as a tool for human learning, addressing its…

Human-Computer Interaction · Computer Science 2024-09-06 Lixiang Yan , Samuel Greiff , Ziwen Teuber , Dragan Gašević

Biochemical networks are used in computational biology, to model the static and dynamical details of systems involved in cell signaling, metabolism, and regulation of gene expression. Parametric and structural uncertainty, as well as…

Molecular Networks · Quantitative Biology 2014-10-15 Ovidiu Radulescu , Alexander N. Gorban , Andrei Zinovyev , Vincent Noel

Assessment of medication history-taking has traditionally relied on human observation, limiting scalability and detailed performance data. While Generative AI (GenAI) platforms enable extensive data collection and learning analytics provide…

In large organisations, knowledge is mainly shared in meetings, which takes up significant amounts of work time. Additionally, frequent in-person meetings produce inconsistent documentation -- official minutes, personal notes, presentations…

Computation and Language · Computer Science 2025-07-23 Simon Baeuerle , Max Radyschevski , Ulrike Pado

Background. Dynamical models of gene regulatory networks (GRNs) are highly effective in describing complex biological phenomena and processes, such as cell differentiation and cancer development. Yet, the topological and functional…

Molecular Networks · Quantitative Biology 2015-08-17 Andrea Paroni , Alex Graudenzi , Giulio Caravagna , Chiara Damiani , Giancarlo Mauri , Marco Antoniotti

In order to fully exploit the potential of molecular communication (MC) for intra-body communication, practically implementable cellular receivers are an important long-term goal. A variety of receiver architectures based on chemical…

Emerging Technologies · Computer Science 2023-05-11 Bastian Heinlein , Lukas Brand , Malcolm Egan , Maximilian Schäfer , Robert Schober , Sebastian Lotter

The development of novel pharmaceuticals represents a significant challenge in modern science, with substantial costs and time investments. Deep generative models have emerged as promising tools for accelerating drug discovery by…

Atomic Physics · Physics 2025-05-20 Adarsh Singh

Natural disasters, including earthquakes, wildfires and cyclones, bear a huge risk on human lives as well as infrastructure assets. An effective response to disaster depends on the ability to rapidly and efficiently assess the intensity of…

Computers and Society · Computer Science 2025-09-03 Aman Raj , Lakshit Arora , Sanjay Surendranath Girija , Shashank Kapoor , Dipen Pradhan , Ankit Shetgaonkar

Motivation: Cell-biological processes are regulated through a complex network of interactions between genes and their products. The processes, their activating conditions, and the associated transcriptional responses are often unknown.…

Molecular Networks · Quantitative Biology 2012-02-03 Leo Lahti , Juha E. A. Knuuttila , Samuel Kaski

With the increasing demand for high-quality internet services, deploying GPON/Fiber-to-the-Home networks is one of the biggest challenges that internet providers have to deal with due to the significant investments involved. Automated…

Neural and Evolutionary Computing · Computer Science 2023-04-04 João Correia , Gustavo Gama , João Tiago Guerrinha , Ricardo Cadime , Pedro Antero Carvalhido , Tiago Vieira , Nuno Lourenço

Generative AI (GenAI) is reshaping enterprise architecture work in agile software organizations, yet evidence on its effects remains scattered. We report a systematic literature review (SLR), following established SLR protocols of…

Software Engineering · Computer Science 2025-10-28 Stefan Julian Kooy , Jean Paul Sebastian Piest , Rob Henk Bemthuis

Character design in games involves interdisciplinary collaborations, typically between designers who create the narrative content, and illustrators who realize the design vision. However, traditional workflows face challenges in…

Human-Computer Interaction · Computer Science 2025-08-19 Long Ling , Xinyi Chen , Ruoyu Wen , Toby Jia-Jun Li , Ray LC

While Generative AI (GenAI) systems draw users away from (Q&A) forums, they also depend on the very data those forums produce to improve their performance. Addressing this paradox, we propose a framework of sequential interaction, in which…

Artificial Intelligence · Computer Science 2026-05-01 Niv Fono , Yftah Ziser , Omer Ben-Porat

A chemical reaction mechanism (CRM) is a sequence of molecular-level events involving bond-breaking/forming processes, generating transient intermediates along the reaction pathway as reactants transform into products. Understanding such…

Chemical Physics · Physics 2024-07-16 Ajnabiul Hoque , Manajit Das , Mayank Baranwal , Raghavan B. Sunoj

Data mining and data classification over biomedical data are two of the most important research fields in computer science. Among the great diversity of techniques that can be used for this purpose, Artifical Neural Networks (ANNs) is one…

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