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Sparked by innovations in generative artificial intelligence (AI), the field of protein design has undergone a paradigm shift with an explosion of new models for optimizing existing enzymes or creating them from scratch. After more than one…

Biomolecules · Quantitative Biology 2026-02-04 Lasse Middendorf , Noelia Ferruz

The integration of artificial intelligence (AI) in early-stage drug discovery offers unprecedented opportunities for exploring chemical space and accelerating hit-to-lead optimization. However, docking optimization in generative approaches…

Quantitative Methods · Quantitative Biology 2025-10-03 Ekaterina Podplutova , Anastasia Vepreva , Olga A. Konovalova , Vladimir Vinogradov , Dmitrii O. Shkil , Andrei Dmitrenko

Artificial neurons built on synthetic gene networks have potential applications ranging from complex cellular decision-making to bioreactor regulation. Furthermore, due to the high information throughput of natural systems, it provides an…

Neural and Evolutionary Computing · Computer Science 2020-01-31 Sihao Huang

Traditional drug discovery programs are being transformed by the advent of machine learning methods. Among these, Generative AI methods (GM) have gained attention due to their ability to design new molecules and enhance specific properties…

Generative AI (GenAI) is rapidly advancing the field of Autonomous Driving (AD), extending beyond traditional applications in text, image, and video generation. We explore how generative models can enhance automotive tasks, such as static…

Deep learning has recently been applied to various research areas of design optimization. This study presents the need and effectiveness of adopting deep learning for generative design (or design exploration) research area. This work…

Machine Learning · Computer Science 2020-05-27 Sangeun Oh , Yongsu Jung , Seongsin Kim , Ikjin Lee , Namwoo Kang

The Gene Regulatory Network (GRN) of biological cells governs a number of key functionalities that enables them to adapt and survive through different environmental conditions. Close observation of the GRN shows that the structure and…

Neural and Evolutionary Computing · Computer Science 2023-10-10 Adrian Ratwatte , Samitha Somathilaka , Sasitharan Balasubramaniam , Assaf A. Gilad

Gene regulatory networks (GRNs) play a central role in cellular decision-making. Understanding their structure and how it impacts their dynamics constitutes thus a fundamental biological question. GRNs are frequently modeled as Boolean…

Molecular Networks · Quantitative Biology 2024-01-19 Claus Kadelka , Taras-Michael Butrie , Evan Hilton , Jack Kinseth , Addison Schmidt , Haris Serdarevic

The objective of this research is to introduce a network specialized in predicting drugs that can be repurposed by investigating real-world evidence sources, such as clinical trials and biomedical literature. Specifically, it aims to…

Artificial Intelligence · Computer Science 2024-06-28 Ahmed Abdeen Hamed , Tamer E. Fandy

Generative AI (GenAI), exemplified by Large Language Models (LLMs) such as OpenAI's ChatGPT, is revolutionizing various fields. Central to this transformation is Data Center Networking (DCN), which not only provides the computational power…

Networking and Internet Architecture · Computer Science 2024-09-17 Yinqiu Liu , Hongyang Du , Dusit Niyato , Jiawen Kang , Zehui Xiong , Yonggang Wen , Dong In Kim

Diagrams are crucial for communicating complex information, yet creating and modifying them remains a labor-intensive task. We present GenAI-DrawIO-Creator, a novel framework that leverages Large Language Models (LLMs) to automate diagram…

Graphics · Computer Science 2026-03-24 Jinze Yu , Dayuan Jiang

Generative AI (GenAI) systems offer unprecedented opportunities for transforming professional and personal work, yet present challenges around prompting, evaluating and relying on outputs, and optimizing workflows. We argue that…

Human-Computer Interaction · Computer Science 2024-07-08 Lev Tankelevitch , Viktor Kewenig , Auste Simkute , Ava Elizabeth Scott , Advait Sarkar , Abigail Sellen , Sean Rintel

Generative AI (GenAI) models excel in their ability to recognize patterns in existing data and generate new and unexpected content. Recent advances have motivated applications of GenAI tools (e.g., Stable Diffusion, ChatGPT) to professional…

Human-Computer Interaction · Computer Science 2023-06-05 Matthew K. Hong , Shabnam Hakimi , Yan-Ying Chen , Heishiro Toyoda , Charlene Wu , Matt Klenk

Generative Artificial Intelligence (GenAI) models such as LLMs, GPTs, and Diffusion Models have recently gained widespread attention from both the research and the industrial communities. This survey explores their application in network…

Networking and Internet Architecture · Computer Science 2025-04-14 Giampaolo Bovenzi , Francesco Cerasuolo , Domenico Ciuonzo , Davide Di Monda , Idio Guarino , Antonio Montieri , Valerio Persico , Antonio Pescapè

Generative Artificial Intelligence (GenAI) and communication networks are expected to have groundbreaking synergies for 6G. Connecting GenAI agents via a wireless network can potentially unleash the power of Collective Intelligence (CI) and…

Artificial Intelligence · Computer Science 2025-05-06 Hang Zou , Qiyang Zhao , Samson Lasaulce , Lina Bariah , Mehdi Bennis , Merouane Debbah

Gene Regulatory Networks (GRNs) are intricate biological systems that control gene expression and regulation in response to environmental and developmental cues. Advances in computational biology, coupled with high throughput sequencing…

Machine Learning · Computer Science 2025-04-18 Akshata Hegde , Tom Nguyen , Jianlin Cheng

Understanding the complex and stochastic nature of Gene Regulatory Networks (GRNs) remains a central challenge in systems biology. Existing modeling paradigms often struggle to effectively capture the intricate, multi-factor regulatory…

Molecular Networks · Quantitative Biology 2025-08-20 Yiyang Jia , Zheng Wei , Zheng Yang , Guohong Peng

Chemical reactions occur in energy, environmental, biological, and many other natural systems, and the inference of the reaction networks is essential to understand and design the chemical processes in engineering and life sciences. Yet,…

Molecular Networks · Quantitative Biology 2021-01-22 Weiqi Ji , Sili Deng

Generative Artificial Intelligence (GenAI) constitutes a transformative technological wave that reconfigures industries through its unparalleled capabilities for content creation, reasoning, planning, and multimodal understanding. This…

Generative Artificial Intelligence (GenAI) applies models and algorithms such as Large Language Model (LLM) and Foundation Model (FM) to generate new data. GenAI, as a promising approach, enables advanced capabilities in various…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-25 Mozhgan Navardi , Romina Aalishah , Yuzhe Fu , Yueqian Lin , Hai Li , Yiran Chen , Tinoosh Mohsenin