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In practically every industry today, artificial intelligence is one of the most effective ways for machines to assist humans. Since its inception, a large number of researchers throughout the globe have been pioneering the application of…

Quantitative Methods · Quantitative Biology 2022-05-09 Chottiwatt Jittprasong

Powerful foundation models, including large language models (LLMs), with Transformer architectures have ushered in a new era of Generative AI across various industries. Industry and research community have witnessed a large number of new…

Protein engineering is an emerging field in biotechnology that has the potential to revolutionize various areas, such as antibody design, drug discovery, food security, ecology, and more. However, the mutational space involved is too vast…

Biomolecules · Quantitative Biology 2023-07-28 Yuchi Qiu , Guo-Wei Wei

Purpose: Proton therapy provides superior dose conformity compared to photon therapy, but its treatment planning is challenged by sensitivity to anatomical changes, setup/range uncertainties, and computational complexity. This review…

Attention-based models trained on protein sequences have demonstrated incredible success at classification and generation tasks relevant for artificial intelligence-driven protein design. However, we lack a sufficient understanding of how…

Machine Learning · Computer Science 2022-06-29 Erik Nijkamp , Jeffrey Ruffolo , Eli N. Weinstein , Nikhil Naik , Ali Madani

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Machine learning has made tremendous progress in recent years and received large amounts of public attention. Though we are still far from designing a full artificially intelligent agent, machine learning has brought us many applications in…

Machine Learning · Computer Science 2019-08-29 Steven Abreu

Recently, there has been great interest in developing Artificial Intelligence (AI) enabled computer-aided diagnostics solutions for the diagnosis of skin cancer. With the increasing incidence of skin cancers, low awareness among a growing…

Image and Video Processing · Electrical Eng. & Systems 2020-06-23 Manu Goyal , Thomas Knackstedt , Shaofeng Yan , Saeed Hassanpour

Although artificial intelligence (AI) has made significant progress in understanding molecules in a wide range of fields, existing models generally acquire the single cognitive ability from the single molecular modality. Since the hierarchy…

Machine Learning · Computer Science 2022-09-14 Bing Su , Dazhao Du , Zhao Yang , Yujie Zhou , Jiangmeng Li , Anyi Rao , Hao Sun , Zhiwu Lu , Ji-Rong Wen

Thanks to the remarkable human-like capabilities of machine learning (ML) models in perceptual and cognitive tasks, frameworks integrating ML within rational agent architectures are gaining traction. Yet, the landscape remains fragmented…

Artificial Intelligence · Computer Science 2025-10-24 Andrea Agiollo , Andrea Omicini

This article details the advances made to a system that uses artificial intelligence to identify alarming student responses. This system is built into our assessment platform to assess whether a student's response indicates they are a…

Computation and Language · Computer Science 2023-05-16 Christopher M. Ormerod , Milan Patel , Harry Wang

The mammalian adaptive immune system has evolved over millions of years to become an incredibly effective defense against foreign antigens. The adaptive immune system's humoral response creates plasma B cells and memory B cells, each with…

Cell Behavior · Quantitative Biology 2021-06-21 Stephen Lindsly , Maya Gupta , Cooper Stansbury , Indika Rajapakse

Language is crucial for human intelligence, but what exactly is its role? We take language to be a part of a system for understanding and communicating about situations. The human ability to understand and communicate about situations…

Computation and Language · Computer Science 2020-07-07 James L. McClelland , Felix Hill , Maja Rudolph , Jason Baldridge , Hinrich Schütze

Therapeutic antibody candidates often require extensive engineering to improve key functional and developability properties before clinical development. This can be achieved through iterative design, where starting molecules are optimized…

Machine Learning · Computer Science 2025-09-23 Aniruddh Raghu , Sebastian Ober , Maxwell Kazman , Hunter Elliott

AI models underpin data-centric applications from image and text processing to scientific discovery in biology, physics, and chemistry. Yet developing them remains heavily manual, requiring practitioners to design architectures, build…

Artificial Intelligence · Computer Science 2026-05-28 Ruiyi Zhang , Peijia Qin , Qi Cao , Li Zhang , Pengtao Xie

Artificial Intelligence (AI) is gradually changing the practice of surgery with the advanced technological development of imaging, navigation and robotic intervention. In this article, the recent successful and influential applications of…

Medical Physics · Physics 2020-01-06 Xiao-Yun Zhou , Yao Guo , Mali Shen , Guang-Zhong Yang

The integration of Agentic AI into scientific discovery marks a new frontier in research automation. These AI systems, capable of reasoning, planning, and autonomous decision-making, are transforming how scientists perform literature…

Computation and Language · Computer Science 2025-03-13 Mourad Gridach , Jay Nanavati , Khaldoun Zine El Abidine , Lenon Mendes , Christina Mack

Pathology has played a crucial role in the diagnosis and evaluation of patient tissue samples obtained from surgeries and biopsies for many years. The advent of Whole Slide Scanners and the development of deep learning technologies have…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Mieko Ochi , Daisuke Komura , Shumpei Ishikawa

As wireless communication evolves, each generation of networks brings new technologies that change how we connect and interact. Artificial Intelligence (AI) is becoming crucial in shaping the future of sixth-generation (6G) networks. By…

Networking and Internet Architecture · Computer Science 2026-04-06 Constantina Chatzieleftheriou , Eirini Liotou

Following antigen stimulation, the net outcomes of a T cell response are shaped by integrated signals from both positive co-stimulatory and negative regulatory molecules. Recently, the blockade of negative regulatory molecules (i.e. immune…

Cell Behavior · Quantitative Biology 2017-09-19 Haidong Dong , Yiyi Yan , Roxana S. Dronca , Svetomir N. Markovic