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Promptable segmentation foundation models such as SAM3 have demonstrated strong generalization capabilities through interactive and concept-based prompting. However, their direct applicability to medical image segmentation remains limited…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Chongcong Jiang , Tianxingjian Ding , Chuhan Song , Jiachen Tu , Ziyang Yan , Yihua Shao , Zhenyi Wang , Yuzhang Shang , Tianyu Han , Yu Tian

Promptable Foundation Models (FMs), initially introduced for natural image segmentation, have also revolutionized medical image segmentation. The increasing number of models, along with evaluations varying in datasets, metrics, and compared…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Caroline Magg , Maaike A. ter Wee , Johannes G. G. Dobbe , Geert J. Streekstra , Leendert Blankevoort , Clara I. Sánchez , Hoel Kervadec

Promptable segmentation models (e.g., the Segment Anything Models) enable generalizable, zero-shot segmentation across diverse domains. Although predictions are deterministic for a fixed image-prompt pair, the robustness of these models to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Elodie Germani , Krystel Nyangoh-Timoh , Pierre Jannin , John S H Baxter

While emerging 3D medical foundation models are envisioned as versatile tools with offer general-purpose capabilities, their validation remains largely confined to regional and structural imaging, leaving a significant modality discrepancy…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yichi Zhang , Feiyang Xiao , Le Xue , Wenbo Zhang , Gang Feng , Chenguang Zheng , Yuan Qi , Yuan Cheng , Zixin Hu

To address prevalent issues in medical imaging, such as data acquisition challenges and label availability, transfer learning from natural to medical image domains serves as a viable strategy to produce reliable segmentation results.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

Interactive segmentation model leverages prompts from users to produce robust segmentation. This advancement is facilitated by prompt engineering, where interactive prompts serve as strong priors during test-time. However, this is an…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

In this paper, we present PRISM, a Promptable and Robust Interactive Segmentation Model, aiming for precise segmentation of 3D medical images. PRISM accepts various visual inputs, including points, boxes, and scribbles as sparse prompts, as…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical…

Adapting large pre-trained foundation models, e.g., SAM, for medical image segmentation remains a significant challenge. A crucial step involves the formulation of a series of specialized prompts that incorporate specific clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Xiuqi Zheng , Yuhang Zhang , Haoran Zhang , Hongrui Liang , Xueqi Bao , Zhuqing Jiang , Qicheng Lao

Medical image segmentation is a crucial and time-consuming task in clinical care, where mask precision is extremely important. The Segment Anything Model (SAM) offers a promising approach, as it provides an interactive interface based on…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Julien Khlaut , Elodie Ferreres , Daniel Tordjman , Hélène Philippe , Tom Boeken , Pierre Manceron , Corentin Dancette

Deep learning offers transformative potential in medical imaging, yet its clinical adoption is frequently hampered by challenges such as data scarcity, distribution shifts, and the need for robust task generalization. Prompt-based…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Hao Yang , Xinlong Liang , Zhang Li , Yue Sun , Zheyu Hu , Xinghe Xie , Behdad Dashtbozorg , Jincheng Huang , Shiwei Zhu , Luyi Han , Jiong Zhang , Shanshan Wang , Ritse Mann , Qifeng Yu , Tao Tan

Interactive 3D biomedical image segmentation requires efficient models that can iteratively refine predictions based on user prompts. Current foundation models either lack volumetric awareness or suffer from limited interactive…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Tidiane Camaret Ndir , Alexander Pfefferle , Robin Tibor Schirrmeister

Due to the flexibility of prompting, foundation models have become the dominant force in the domains of natural language processing and image generation. With the recent introduction of the Segment Anything Model (SAM), the prompt-driven…

Image and Video Processing · Electrical Eng. & Systems 2023-08-14 Yichi Zhang , Rushi Jiao

Despite advances in deep learning, robustness under domain shift remains a major bottleneck in medical imaging settings. Findings on natural images suggest that deep neural models can show a strong textural bias when carrying out image…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Seoin Chai , Daniel Rueckert , Ahmed E. Fetit

Existing promptable segmentation methods in the medical imaging field primarily consider either textual or visual prompts to segment relevant objects, yet they often fall short when addressing anomalies in medical images, like tumors, which…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Zhongzhen Huang , Yankai Jiang , Rongzhao Zhang , Shaoting Zhang , Xiaofan Zhang

The Segment Anything Model (SAM) can achieve satisfactory segmentation performance under high-quality box prompts. However, SAM's robustness is compromised by the decline in box quality, limiting its practicality in clinical reality. In…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Yuhao Huang , Xin Yang , Han Zhou , Yan Cao , Haoran Dou , Fajin Dong , Dong Ni

Due to the increase in computational resources and accessibility of data, an increase in large, deep learning models trained on copious amounts of multi-modal data using self-supervised or semi-supervised learning have emerged. These…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Madeline Chantry Schiappa , Shehreen Azad , Sachidanand VS , Yunhao Ge , Ondrej Miksik , Yogesh S. Rawat , Vibhav Vineet

Due to the inherent flexibility of prompting, foundation models have emerged as the predominant force in the fields of natural language processing and computer vision. The recent introduction of the Segment Anything Model (SAM) signifies a…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Yichi Zhang , Zhenrong Shen , Rushi Jiao

The accurate segmentation of medical images is a crucial step in obtaining reliable morphological statistics. However, training a deep neural network for this task requires a large amount of labeled data to ensure high-accuracy results. To…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Xianjun Han , Qianqian Chen , Zhaoyang Xie , Xuejun Li , Hongyu Yang

The Segment Anything Model (SAM) has recently emerged as a groundbreaking foundation model for prompt-driven image segmentation tasks. However, both the original SAM and its medical variants require slice-by-slice manual prompting of target…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yichi Zhang , Shiyao Hu , Sijie Ren , Chen Jiang , Yuan Cheng , Yuan Qi
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