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We formulate and analyze a novel hypothesis testing problem for inferring the edge structure of an infection graph. In our model, a disease spreads over a network via contagion or random infection, where the random variables governing the…

Statistics Theory · Mathematics 2020-05-05 Justin Khim , Po-Ling Loh

This paper describes a novel approach to modeling homphily, i.e. the tendency of nodes that share (or differ in) certain attributes to be linked; we consider dynamic networks in which nodes can be added over time but not removed. Our…

Genomics · Quantitative Biology 2022-01-13 V. DeGruttola , M. Nakazawa , J. Liu , X. Tu , S. Little , S. Mehta

Diffusion-based generative graph models have been proven effective in generating high-quality small graphs. However, they need to be more scalable for generating large graphs containing thousands of nodes desiring graph statistics. In this…

Machine Learning · Computer Science 2023-06-01 Xiaohui Chen , Jiaxing He , Xu Han , Li-Ping Liu

Dynamic models have been successfully used in producing estimates of HIV epidemics at national level, due to their epidemiological nature and their ability to simultaneously estimate prevalence, incidence, and mortality rates. Recently, HIV…

Methodology · Statistics 2016-02-19 Le Bao , Ben Sheng , Xiaoyue Niu , Yuan Tang , Tim Brown , Peter D. Ghys , Jeff W. Eaton

For the purpose of maximizing the spread of influence caused by a certain small number k of nodes in a social network, we are asked to find a k-subset of nodes (i.e., a seed set) with the best capacity to influence the nodes not in it. This…

Social and Information Networks · Computer Science 2022-06-07 Enqiang Zhu , Haosen Wang , Yu Zhang , Kai Zhang , Chanjuan Liu

Disease-gene prediction (DGP) refers to the computational challenge of predicting associations between genes and diseases. Effective solutions to the DGP problem have the potential to accelerate the therapeutic development pipeline at early…

Machine Learning · Computer Science 2019-07-15 Vikash Singh , Pietro Lio'

One of the cornerstones in combating the HIV pandemic is being able to assess the current state and evolution of local HIV epidemics. This remains a complex problem, as many HIV infected individuals remain unaware of their infection status,…

Populations and Evolution · Quantitative Biology 2019-10-24 Pieter Libin , Nassim Versbraegen , Ana B. Abecasis , Perpetua Gomes , Tom Lenaerts , Ann Nowé

It is the main purpose of this paper to introduce a graph-valued stochastic process in order to model the spread of a communicable infectious disease. The major novelty of the SIR model we promote lies in the fact that the social network on…

Applications · Statistics 2014-02-06 Charanpal Dhanjal , Stéphan Clémençon

A central challenge in Human Immunodeficiency Virus (HIV) public health policy lies in determining whether to universally expand treatment access, despite the risk of sub-optimal adherence and consequent drug resistance, or to adopt a more…

Quantitative Methods · Quantitative Biology 2025-07-16 Ashish Poonia , Siddhartha P. Chakrabarty

Background: High HIV transmission persists in many U.S. jurisdictions despite prevention efforts. HIV self-testing offers a means to overcome barriers associated with routine laboratory-based testing but carries a risk of increasing…

Dynamical Systems · Mathematics 2025-04-23 Alex Viguerie

In this paper we investigate a susceptible-infected-susceptible (SIS) epidemic model describing data dissemination in opportunistic networks with heterogeneous setting of transmission parameters. We obtained the estimation of the final…

Social and Information Networks · Computer Science 2014-03-28 Vadim Alexeev , Liudmila Rozanova , Alexander Temerev

We study a sequential decision-making problem on a $n$-node graph $\mathcal{G}$ where each node has an unknown label from a finite set $\mathbf{\Omega}$, drawn from a joint distribution $\mathcal{P}$ that is Markov with respect to…

Artificial Intelligence · Computer Science 2025-10-30 Davin Choo , Yuqi Pan , Tonghan Wang , Milind Tambe , Alastair van Heerden , Cheryl Johnson

Dynamic models have been successfully used in producing estimates of HIV epidemics at the national level due to their epidemiological nature and their ability to estimate prevalence, incidence, and mortality rates simultaneously. Recently,…

Methodology · Statistics 2024-01-11 Le Bao , Xiaoyue Niu , Tim Brown , Jeffrey W. Imai-Eaton

Graph-based semi-supervised learning is a fundamental machine learning problem, and has been well studied. Most studies focus on homogeneous networks (e.g. citation network, friend network). In the present paper, we propose the…

Social and Information Networks · Computer Science 2018-07-10 Cheng Ju , James Li , Bram Wasti , Shengbo Guo

Hypergraphs are powerful mathematical structures that can model complex, high-order relationships in various domains, including social networks, bioinformatics, and recommender systems. However, generating realistic and diverse hypergraphs…

Machine Learning · Computer Science 2026-03-11 Dorian Gailhard , Enzo Tartaglione , Lirida Naviner , Jhony H. Giraldo

Predicting drug-gene associations is crucial for drug development and disease treatment. While graph neural networks (GNN) have shown effectiveness in this task, they face challenges with data sparsity and efficient contrastive learning…

Machine Learning · Computer Science 2025-02-14 Jiayang Wu , Wensheng Gan , Philip S. Yu

Pre-exposure prophylaxis (PrEP) is an effective intervention for preventing HIV transmission, but high cost and uneven uptake raise challenges for resource allocation. While spillover effects, wherein PrEP use in one group reduces…

Dynamical Systems · Mathematics 2026-02-06 Chiara Piazzola , Salman Safdar , Alex Viguerie , Abba B. Gumel

Statistical models for networks with complex dependencies pose particular challenges for model selection and evaluation. In particular, many well-established statistical tools for selecting between models assume conditional independence of…

Methodology · Statistics 2019-08-20 Fan Yin , Nolan Edward Phillips , Carter T. Butts

From social networks to protein complexes to disease genomes to visual data, hypergraphs are everywhere. However, the scope of research studying deep learning on hypergraphs is still quite sparse and nascent, as there has not yet existed an…

Machine Learning · Computer Science 2019-10-08 Josh Payne

The use of network theory to model disease propagation on populations introduces important elements of reality to the classical epidemiological models. The use of random geometric graphs (RGG) is one of such network models that allows for…

Physics and Society · Physics 2016-12-21 Ernesto Estrada , Sandro Meloni , Matthew Sheerin , Yamir Moreno
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