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We design and implement a quantum combinatorial reasoning framework for large language models (QCR-LLM), integrating a real quantum computer in the hybrid workflow. QCR-LLM reformulates reasoning aggregation as a higher-order unconstrained…

Quantum machine learning has emerged as a promising approach for medical image analysis, particularly in settings where compact models and expressive feature representations are desired. This paper presents a hybrid classical--quantum…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Shabnam Sodagari , Tommy Long

Effective molecular representations are essential for ligand-based virtual screening. We investigate how quantum data embedding strategies can improve this task by developing and evaluating a family of quantum-classical hybrid embedding…

Quantum Physics · Physics 2025-12-19 Junggu Choi , Tak Hur , Seokhoon Jeong , Kyle L. Jung , Jun Bae Park , Junho Lee , Jae U. Jung , Daniel K. Park

Financial services is a prospect industry where unlocked near-term quantum utility could yield profitable potential, and, in particular, quantum machine learning algorithms could potentially benefit businesses by improving the quality of…

Quantum Transfer Learning (QTL) offers a promising approach for visual quantum machine learning under near-term constraints, where limited qubit counts, shallow circuit depths, and costly hybrid optimization restrict end-to-end quantum…

Quantum Physics · Physics 2026-05-20 Nouhaila Innan , Saim Rehman , Muhammad Shafique

Current quantum systems have significant limitations affecting the processing of large datasets with high dimensionality, typical of high energy physics. In the present paper, feature and data prototype selection techniques were studied to…

High Energy Physics - Phenomenology · Physics 2023-12-18 Miguel Caçador Peixoto , Nuno Filipe Castro , Miguel Crispim Romão , Maria Gabriela Jordão Oliveira , Inês Ochoa

Large Language Models (LLMs) have recently demonstrated strong potential for cybersecurity question answering (QA), supporting decision-making in real-time threat detection and response workflows. However, their substantial computational…

Cryptography and Security · Computer Science 2025-09-18 Onat Gungor , Roshan Sood , Harold Wang , Tajana Rosing

We study the fault tolerance of quantum computation by adiabatic evolution, a quantum algorithm for solving various combinatorial search problems. We describe an inherent robustness of adiabatic computation against two kinds of errors,…

Quantum Physics · Physics 2007-05-23 Andrew M. Childs , Edward Farhi , John Preskill

Recent advancements in quantum computing (QC) and machine learning (ML) have garnered significant attention, leading to substantial efforts toward the development of quantum machine learning (QML) algorithms to address a variety of complex…

Quantum Physics · Physics 2024-12-18 Samuel Yen-Chi Chen

Due to the rise in antimicrobial resistance, identifying novel compounds with antibiotic potential is crucial for combatting this global health issue. However, traditional drug development methods are costly and inefficient. Recognizing the…

Biomolecules · Quantitative Biology 2025-02-18 Gen Zhou , Sugitha Janarthanan , Yutong Lu , Pingzhao Hu

Adiabatic quantum computers can solve difficult optimization problems (e.g., the quadratic unconstrained binary optimization problem), and they seem well suited to train machine learning models. In this paper, we describe an adiabatic…

Adversarial learning is one of the most successful approaches to modelling high-dimensional probability distributions from data. The quantum computing community has recently begun to generalize this idea and to look for potential…

Quantum Physics · Physics 2019-04-17 Marcello Benedetti , Edward Grant , Leonard Wossnig , Simone Severini

Quantum machine learning is considered one of the current research fields with immense potential. In recent years, Havl\'i\v{c}ek et al. [Nature 567, 209-212 (2019)] have proposed a quantum machine learning algorithm with quantum-enhanced…

Quantum Physics · Physics 2025-06-09 Chao Ding , Shi Wang , Yaonan Wang , Weibo Gao

Quantum machine learning has the potential to provide powerful algorithms for artificial intelligence. The pursuit of quantum advantage in quantum machine learning is an active area of research. For current noisy, intermediate-scale quantum…

Quantum Physics · Physics 2023-05-11 Rui Yang , Samuel Bosch , Bobak Kiani , Seth Lloyd , Adrian Lupascu

We investigate the possibility to apply quantum machine learning techniques for data analysis, with particular regard to an interesting use-case in high-energy physics. We propose an anomaly detection algorithm based on a parametrized…

Quantum Physics · Physics 2026-04-21 Simone Bordoni , Denis Stanev , Tommaso Santantonio , Stefano Giagu

Quantum annealing is a general strategy for solving difficult optimization problems with the aid of quantum adiabatic evolution. Both analytical and numerical evidence suggests that under idealized, closed system conditions, quantum…

Background: Quantitative susceptibility mapping (QSM) of the brain is an advanced MRI technique for assessing tissue characteristics based on magnetic susceptibility, which varies with the composition of the tissue, such as iron, calcium,…

Quantum communication has been leading the way of many remarkable theoretical results and experimental tests in physics. In this context, quantum communication complexity (QCC) has recently drawn earnest research attention as a tool to…

Quantum Physics · Physics 2020-11-11 Hipólito Gómez-Sousa

Antibiotics are a vital class of drugs closely associated with the prevention and treatment of bacterial infections. Accurate prediction of molecular antimicrobial activity remains a key challenge in the pursuit of novel antibiotic…

Quantitative Methods · Quantitative Biology 2025-09-23 R. He

This paper explores the applications of quantum annealing (QA) and classical simulated annealing (SA) to a suite of combinatorial optimization problems in machine learning, namely feature selection, instance selection, and clustering. We…

Quantum Physics · Physics 2025-07-22 Chloe Pomeroy , Aleksandar Pramov , Karishma Thakrar , Lakshmi Yendapalli