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Related papers: Domain-Specific Knowledge Graphs in RAG-Enhanced H…

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Retrieval-Augmented Generation (RAG) enhances LLM factuality, but multi-domain applications face challenges like lack of diverse benchmarks and poor out-of-domain generalization. The first contribution of this work is to introduce a diverse…

Computation and Language · Computer Science 2025-04-04 Alexandre Misrahi , Nadezhda Chirkova , Maxime Louis , Vassilina Nikoulina

Retrieval-augmented generation (RAG) enhances the question-answering (QA) abilities of large language models (LLMs) by integrating external knowledge. However, adapting general-purpose RAG systems to specialized fields such as science and…

Computation and Language · Computer Science 2025-01-28 Ran Xu , Hui Liu , Sreyashi Nag , Zhenwei Dai , Yaochen Xie , Xianfeng Tang , Chen Luo , Yang Li , Joyce C. Ho , Carl Yang , Qi He

Large language models (LLMs) are increasingly used in the mental health domain, yet it remains unclear how well they capture related biomedical knowledge and how reliably they apply it to clinically salient structured judgments. Here, we…

Computation and Language · Computer Science 2026-05-18 Weixin Liu , Congning Ni , Shelagh A. Mulvaney , Susannah L. Rose , Murat Kantarcioglu , Bradley A. Malin , Zhijun Yin

Retrieval-Augmented Generation (RAG) systems for biomedical literature are typically evaluated using ranking metrics like Mean Reciprocal Rank (MRR), which measure how well the system identifies the single most relevant chunk. We argue that…

Artificial Intelligence · Computer Science 2026-03-25 Pouria Mortezaagha , Arya Rahgozar

Recent advancements in Large Language Models (LLMs) have transformed Natural Language Processing (NLP), enabling complex information retrieval and generation tasks. Retrieval-Augmented Generation (RAG) has emerged as a key innovation,…

Information Retrieval · Computer Science 2026-02-27 Teri Rumble , Zbyněk Gazdík , Javad Zarrin , Jagdeep Ahluwalia

Graph-based RAG constructs a knowledge graph (KG) from text chunks to enhance retrieval in Large Language Model (LLM)-based question answering. It is especially beneficial in domains such as biomedicine, law, and political science, where…

Machine Learning · Computer Science 2025-10-29 Ziyu Liu , Yijing Liu , Jianfei Yuan , Minzhi Yan , Le Yue , Honghui Xiong , Yi Yang

Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by integrating them with an external knowledge base to improve the answer relevance and accuracy. In real-world scenarios, beyond pure text, a substantial amount of…

Computation and Language · Computer Science 2025-10-07 Jiaru Zou , Dongqi Fu , Sirui Chen , Xinrui He , Zihao Li , Yada Zhu , Jiawei Han , Jingrui He

Retrieval-Augmented Generation (RAG) integrates non-parametric knowledge into Large Language Models (LLMs), typically from unstructured texts and structured graphs. While recent progress has advanced text-based RAG to multi-turn reasoning…

Computation and Language · Computer Science 2025-12-11 Yucan Guo , Miao Su , Saiping Guan , Zihao Sun , Xiaolong Jin , Jiafeng Guo , Xueqi Cheng

Knowledge Graphs (KG) and associated Knowledge Graph Embedding (KGE) models have recently begun to be explored in the context of drug discovery and have the potential to assist in key challenges such as target identification. In the drug…

Biomolecules · Quantitative Biology 2022-06-01 Stephen Bonner , Ian P Barrett , Cheng Ye , Rowan Swiers , Ola Engkvist , Charles Tapley Hoyt , William L Hamilton

Large language models (LLMs) often suffer from hallucination, generating factually incorrect statements when handling questions beyond their knowledge and perception. Retrieval-augmented generation (RAG) addresses this by retrieving…

Computation and Language · Computer Science 2025-11-18 Shengyuan Chen , Chuang Zhou , Zheng Yuan , Qinggang Zhang , Zeyang Cui , Hao Chen , Yilin Xiao , Jiannong Cao , Xiao Huang

Deploying Large Language Models (LLMs) for healthcare question answering requires robust methods to ensure accuracy and reliability. This work introduces Query-Based Retrieval Augmented Generation (QB-RAG), a framework for enhancing…

Machine Learning · Computer Science 2025-07-31 Eric Yang , Jonathan Amar , Jong Ha Lee , Bhawesh Kumar , Yugang Jia

Safe and trustworthy use of Large Language Models (LLM) in the processing of healthcare documents and scientific papers could substantially help clinicians, scientists and policymakers in overcoming information overload and focusing on the…

Accurate healthcare prediction is critical for improving patient outcomes and reducing operational costs. Bolstered by growing reasoning capabilities, large language models (LLMs) offer a promising path to enhance healthcare predictions by…

Artificial Intelligence · Computer Science 2025-11-18 Chuang Zhao , Hui Tang , Hongke Zhao , Xiaofang Zhou , Xiaomeng Li

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

Retrieval-augmented generation (RAG) generally enhances large language models' (LLMs) ability to solve knowledge-intensive tasks. But RAG may also lead to performance degradation due to imperfect retrieval and the model's limited ability to…

Computation and Language · Computer Science 2025-05-29 Shuyang Cao , Karthik Radhakrishnan , David Rosenberg , Steven Lu , Pengxiang Cheng , Lu Wang , Shiyue Zhang

As large language models (LLMs) continue to grow in size, their abilities to tackle complex tasks have significantly improved. However, issues such as hallucination and the lack of up-to-date knowledge largely remain unresolved. Knowledge…

Artificial Intelligence · Computer Science 2026-03-17 Lihui Liu

Recent studies in medical question answering (Medical QA) have actively explored the integration of large language models (LLMs) with biomedical knowledge graphs (KGs) to improve factual accuracy. However, most existing approaches still…

Computation and Language · Computer Science 2026-01-15 Chaerin Lee , Sohee Park , Hyunsik Na , Daseon Choi

Large Language Models (LLMs) showcase impressive capabilities but encounter challenges like hallucination, outdated knowledge, and non-transparent, untraceable reasoning processes. Retrieval-Augmented Generation (RAG) has emerged as a…

Computation and Language · Computer Science 2024-03-28 Yunfan Gao , Yun Xiong , Xinyu Gao , Kangxiang Jia , Jinliu Pan , Yuxi Bi , Yi Dai , Jiawei Sun , Meng Wang , Haofen Wang

Knowledge Graph-based recommendations have gained significant attention due to their ability to leverage rich semantic relationships. However, constructing and maintaining Knowledge Graphs (KGs) is resource-intensive, and the accuracy of…

Information Retrieval · Computer Science 2025-02-07 Rui Cai , Chao Wang , Qianyi Cai , Dazhong Shen , Hui Xiong

To mitigate the hallucination and knowledge deficiency in large language models (LLMs), Knowledge Graph (KG)-based Retrieval-Augmented Generation (RAG) has shown promising potential by utilizing KGs as external resource to enhance LLMs…

Computation and Language · Computer Science 2025-01-23 Zengyi Gao , Yukun Cao , Hairu Wang , Ao Ke , Yuan Feng , Xike Xie , S Kevin Zhou
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