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With the rapid advancement of generative models, the realism of AI-generated images has significantly improved, posing critical challenges for verifying digital content authenticity. Current deepfake detection methods often depend on…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Jiarui Wang , Huiyu Duan , Juntong Wang , Ziheng Jia , Woo Yi Yang , Xiaorong Zhu , Yu Zhao , Jiaying Qian , Yuke Xing , Guangtao Zhai , Xiongkuo Min

Multimodal large language models (MLLMs) typically extract visual features from the final layers of a pretrained Vision Transformer (ViT). This widespread deep-layer bias, however, is largely driven by empirical convention rather than…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Haoran Chen , Junyan Lin , Xinghao Chen , Yue Fan , Jianfeng Dong , Xin Jin , Hui Su , Jinlan Fu , Xiaoyu Shen

Research on Multi-modal Large Language Models (MLLMs) towards the multi-image cross-modal instruction has received increasing attention and made significant progress, particularly in scenarios involving closely resembling images (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Tao Wu , Mengze Li , Jingyuan Chen , Wei Ji , Wang Lin , Jinyang Gao , Kun Kuang , Zhou Zhao , Fei Wu

The "thinking with images" paradigm represents a pivotal shift in the reasoning of Vision Language Models (VLMs), moving from text-dominant chain-of-thought to image-interactive reasoning. By invoking visual tools or generating intermediate…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Chi Zhang , Haibo Qiu , Qiming Zhang , Zhixiong Zeng , Lin Ma , Jing Zhang

The development of Large Vision-Language Models (LVLMs) is striving to catch up with the success of Large Language Models (LLMs), yet it faces more challenges to be resolved. Very recent works enable LVLMs to localize object-level visual…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Zhipeng Huang , Zhizheng Zhang , Zheng-Jun Zha , Yan Lu , Baining Guo

Large Language Models (LLMs) have made great strides in areas such as language processing and computer vision. Despite the emergence of diverse techniques to improve few-shot learning capacity, current LLMs fall short in handling the…

Biomolecules · Quantitative Biology 2024-05-14 Xianggen Liu , Yan Guo , Haoran Li , Jin Liu , Shudong Huang , Bowen Ke , Jiancheng Lv

Vision-language models (VLMs) unify computer vision and natural language processing in a single architecture capable of interpreting and describing images. Most state-of-the-art systems rely on two computationally intensive components:…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Andrew Kiruluta , Priscilla Burity

The challenge of Multimodal Deformable Image Registration (MDIR) lies in the conversion and alignment of features between images of different modalities. Generative models (GMs) cannot retain the necessary information enough from the source…

Computer Vision and Pattern Recognition · Computer Science 2024-08-21 Mingrui Ma , Weijie Wang , Jie Ning , Jianfeng He , Nicu Sebe , Bruno Lepri

Multimodal Large Language Models (MLLMs) inherit the superior text understanding capabilities of LLMs and extend these capabilities to multimodal scenarios. These models achieve excellent results in the general domain of multimodal tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jinlong He , Pengfei Li , Gang Liu , Shenjun Zhong

Multimodal Large Language Models (MLLMs) have endowed LLMs with the ability to perceive and understand multi-modal signals. However, most of the existing MLLMs mainly adopt vision encoders pretrained on coarsely aligned image-text pairs,…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Gongwei Chen , Leyang Shen , Rui Shao , Xiang Deng , Liqiang Nie

A remarkable ability of human beings resides in compositional reasoning, i.e., the capacity to make "infinite use of finite means". However, current large vision-language foundation models (VLMs) fall short of such compositional abilities…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Junyan Li , Delin Chen , Yining Hong , Zhenfang Chen , Peihao Chen , Yikang Shen , Chuang Gan

3D Visual Grounding (3DVG) focuses on locating objects in 3D scenes based on natural language descriptions, serving as a fundamental task for embodied AI and robotics. Recent advances in Multi-modal Large Language Models (MLLMs) have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Beining Xu , Siting Zhu , Zhao Jin , Junxian Li , Hesheng Wang

This survey and application guide to multimodal large language models(MLLMs) explores the rapidly developing field of MLLMs, examining their architectures, applications, and impact on AI and Generative Models. Starting with foundational…

Artificial Intelligence · Computer Science 2025-12-02 Chia Xin Liang , Pu Tian , Caitlyn Heqi Yin , Yao Yua , Wei An-Hou , Li Ming , Xinyuan Song , Tianyang Wang , Ziqian Bi , Ming Liu

The rapid evolution of artificial intelligence in drug discovery encounters challenges with generalization and extensive training, yet Large Language Models (LLMs) offer promise in reshaping interactions with complex molecular data. Our…

Biomolecules · Quantitative Biology 2024-12-20 He Cao , Zijing Liu , Xingyu Lu , Yuan Yao , Yu Li

Unlike vision and language data which usually has a unique format, molecules can naturally be characterized using different chemical formulations. One can view a molecule as a 2D graph or define it as a collection of atoms located in a 3D…

Machine Learning · Computer Science 2023-03-29 Shengjie Luo , Tianlang Chen , Yixian Xu , Shuxin Zheng , Tie-Yan Liu , Liwei Wang , Di He

We propose a network for semantic mapping called the Dense Dilated Convolutions Merging Network (DDCM-Net) to provide a deep learning approach that can recognize multi-scale and complex shaped objects with similar color and textures, such…

Computer Vision and Pattern Recognition · Computer Science 2019-09-02 Qinghui Liu , Michael Kampffmeyer , Robert Jenssen , Arnt-Børre Salberg

Masked image modeling (MIM) has become a prevalent pre-training setup for vision foundation models and attains promising performance. Despite its success, existing MIM methods discard the decoder network during downstream applications,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Qi Han , Yuxuan Cai , Xiangyu Zhang

The accurate prediction of protein-ligand binding affinity is important for drug discovery yet remains challenging for multi-domain proteins, where inter-domain dynamics and flexible linkers govern molecular recognition. Current geometric…

Quantitative Methods · Quantitative Biology 2026-01-27 Shuo Zhang , Jian K. Liu

Large language models (LLMs) have been effectively used for many computer vision tasks, including image classification. In this paper, we present a simple yet effective approach for zero-shot image classification using multimodal LLMs.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Abdelrahman Abdelhamed , Mahmoud Afifi , Alec Go

Molecular dynamics (MD) has long been the de facto choice for simulating complex atomistic systems from first principles. Recently deep learning models become a popular way to accelerate MD. Notwithstanding, existing models depend on…

Computational Engineering, Finance, and Science · Computer Science 2023-01-10 Fang Wu , Stan Z. Li
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