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Patient simulation is essential for developing and evaluating mental health dialogue systems. As most existing approaches rely on snapshot-style prompts with limited profile information, homogeneous behaviors and incoherent disease…

Computation and Language · Computer Science 2026-03-25 Baihan Li , Bingrui Jin , Kunyao Lan , Ming Wang , Mengyue Wu

In this work, we propose a novel problem formulation for de-identification of unstructured clinical text. We formulate the de-identification problem as a sequence to sequence learning problem instead of a token classification problem. Our…

Computation and Language · Computer Science 2021-09-13 Md Monowar Anjum , Noman Mohammed , Xiaoqian Jiang

The rise of chronic diseases and pandemics like COVID-19 has emphasized the need for effective patient data processing while ensuring privacy through anonymization and de-identification of protected health information (PHI). Anonymized data…

Computation and Language · Computer Science 2024-12-17 Murat Gunay , Bunyamin Keles , Raife Hizlan

Most methods for explaining black-box classifiers (e.g. on tabular data, images, or time series) rely on measuring the impact that removing/perturbing features has on the model output. This forces the explanation language to match the…

Machine Learning · Computer Science 2023-07-10 Alan Perotti , Paolo Bajardi , Francesco Bonchi , André Panisson

Many models are pretrained on redacted text for privacy reasons. Clinical foundation models are often trained on de-identified text, which uses special syntax (masked) text in place of protected health information. Even though these models…

Computation and Language · Computer Science 2025-06-18 Paul Landes , Aaron J Chaise , Tarak Nath Nandi , Ravi K Madduri

Anonymizing text that contains sensitive information is crucial for a wide range of applications. Existing techniques face the emerging challenges of the re-identification ability of large language models (LLMs), which have shown advanced…

Computation and Language · Computer Science 2025-06-19 Tianyu Yang , Xiaodan Zhu , Iryna Gurevych

Physician-physician discussions of patient cases represent a rich source of clinical knowledge and reasoning that could feed AI agents to enrich and even participate in subsequent interactions. However, privacy regulations and ethical…

Computation and Language · Computer Science 2026-04-13 Beny Rubinstein , Sergio Matos

This study examines integrating EHRs and NLP with large language models (LLMs) to improve healthcare data management and patient care. It focuses on using advanced models to create secure, HIPAA-compliant synthetic patient notes for…

Computation and Language · Computer Science 2025-06-03 Yao-Shun Chuang , Atiquer Rahman Sarkar , Yu-Chun Hsu , Noman Mohammed , Xiaoqian Jiang

While Large Language Models (LLMs) excel at generalized reasoning, standard retrieval-augmented approaches fail to address the disconnected nature of long-term agentic memory. To bridge this gap, we introduce Synapse (Synergistic…

Computation and Language · Computer Science 2026-02-17 Hanqi Jiang , Junhao Chen , Yi Pan , Ling Chen , Weihang You , Yifan Zhou , Ruidong Zhang , Andrea Sikora , Lin Zhao , Yohannes Abate , Tianming Liu

Sharing protected health information (PHI) is critical for furthering biomedical research. Before data can be distributed, practitioners often perform deidentification to remove any PHI contained in the text. Contemporary deidentification…

Computation and Language · Computer Science 2024-10-23 John X. Morris , Thomas R. Campion , Sri Laasya Nutheti , Yifan Peng , Akhil Raj , Ramin Zabih , Curtis L. Cole

Large language models (LLMs) have shown promising capabilities in healthcare analysis but face several challenges like hallucinations, parroting, and bias manifestation. These challenges are exacerbated in complex, sensitive, and…

Computation and Language · Computer Science 2024-12-18 Vivek Kumar , Eirini Ntoutsi , Pushpraj Singh Rajawat , Giacomo Medda , Diego Reforgiato Recupero

Anomaly detection in graph-structured data is an inherently challenging problem, as it requires the identification of rare nodes that deviate from the majority in both their structural and behavioral characteristics. Existing methods, such…

Machine Learning · Computer Science 2025-09-16 Mingkang Li , Xuexiong Luo , Yue Zhang , Yaoyang Li , Fu Lin

The reliability of Healthcare Information Systems (HIS) is frequently compromised by human-induced data entry errors, which existing statistical anomaly detection methods fail to distinguish from legitimate clinical extremes. This paper…

Machine Learning · Computer Science 2026-05-18 Abolfazl Zarghani , Amir Malekesfandiari

Exploiting natural language processing in the clinical domain requires de-identification, i.e., anonymization of personal information in texts. However, current research considers de-identification and downstream tasks, such as concept…

Computation and Language · Computer Science 2020-05-20 Lukas Lange , Heike Adel , Jannik Strötgen

We introduce an explainability method for biomedical hypothesis generation systems, built on top of the novel Hypothesis Generation Context Retriever framework. Our approach combines semantic graph-based retrieval and relevant…

Information Retrieval · Computer Science 2025-11-11 Ilya Tyagin , Saeideh Valipour , Aliaksandra Sikirzhytskaya , Michael Shtutman , Ilya Safro

Unstructured textual data is at the heart of healthcare systems. For obvious privacy reasons, these documents are not accessible to researchers as long as they contain personally identifiable information. One way to share this data while…

Cryptography and Security · Computer Science 2022-11-03 Yakini Tchouka , Jean-François Couchot , David Laiymani

Health monitoring systems have revolutionized modern healthcare by enabling the continuous capture of physiological and behavioral data, essential for preventive measures and early health intervention. While integrating this data with Large…

Machine Learning · Computer Science 2024-06-26 Ajan Subramanian , Zhongqi Yang , Iman Azimi , Amir M. Rahmani

The development of AI for mental health is hindered by a lack of authentic therapy dialogues, due to strict privacy regulations and the fact that clinical sessions were historically rarely recorded. We present an LLM-driven pipeline that…

Suicidal ideation detection is critical for real-time suicide prevention, yet its progress faces two under-explored challenges: limited language coverage and unreliable annotation practices. Most available datasets are in English, but even…

Computation and Language · Computer Science 2025-07-22 Amina Dzafic , Merve Kavut , Ulya Bayram

Early and accurate disease detection is crucial for patient management and successful treatment outcomes. However, the automatic identification of anomalies in medical images can be challenging. Conventional methods rely on large labeled…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Cosmin I Bercea , Benedikt Wiestler , Daniel Rueckert , Julia A Schnabel