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The entry of large language models (LLMs) into research and commercial spaces has led to a trend of ever-larger models, with initial promises of generalisability, followed by a widespread desire to downsize and create specialised models…

Computation and Language · Computer Science 2024-02-19 Niall Taylor , Upamanyu Ghose , Omid Rohanian , Mohammadmahdi Nouriborji , Andrey Kormilitzin , David Clifton , Alejo Nevado-Holgado

Large language models (LLMs) are increasingly deployed in clinical decision support, yet subtle demographic cues can influence their reasoning. Prior work has documented disparities in outputs across patient groups, but little is known…

Computation and Language · Computer Science 2025-10-16 Rajarshi Ghosh , Abhay Gupta , Hudson McBride , Anurag Vaidya , Faisal Mahmood

The efficacy of large language models (LLMs) is heavily dependent on the quality of the underlying data, particularly within specialized domains. A common challenge when fine-tuning LLMs for domain-specific applications is the potential…

Computation and Language · Computer Science 2024-03-15 Jianwei Sun , Chaoyang Mei , Linlin Wei , Kaiyu Zheng , Na Liu , Ming Cui , Tianyi Li

Objective: Question answering (QA) systems have the potential to improve the quality of clinical care by providing health professionals with the latest and most relevant evidence. However, QA systems have not been widely adopted. This…

Computation and Language · Computer Science 2024-02-06 Gregory Kell , Angus Roberts , Serge Umansky , Linglong Qian , Davide Ferrari , Frank Soboczenski , Byron Wallace , Nikhil Patel , Iain J Marshall

Large vision language models (LVLMs) have demonstrated impressive performance across a wide range of tasks. These capabilities largely stem from visual instruction tuning, which fine-tunes models on datasets consisting of curated…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Myeongkyun Kang , Soopil Kim , Xiaoxiao Li , Sang Hyun Park

Auscultation is a vital diagnostic tool, yet its utility is often limited by subjective interpretation. While general-purpose Audio-Language Models (ALMs) excel in general domains, they struggle with the nuances of physiological signals. We…

Retrieval-Augmented Generation systems are essential for providing fact-based guidance from Malaysian Clinical Practice Guidelines. However, their effectiveness with image-based queries is limited, as general Vision-Language Model captions…

Computation and Language · Computer Science 2025-11-10 Lee Qi Zun , Mohamad Zulhilmi Bin Abdul Halim , Goh Man Fye

We introduce CUS-QA, a benchmark for evaluation of open-ended regional question answering that encompasses both textual and visual modalities. We also provide strong baselines using state-of-the-art large language models (LLMs). Our dataset…

Computation and Language · Computer Science 2026-02-03 Jindřich Libovický , Jindřich Helcl , Andrei Manea , Gianluca Vico

Recently, the increasing demand for superior medical services has highlighted the discrepancies in the medical infrastructure. With big data, especially texts, forming the foundation of medical services, there is an exigent need for…

Computation and Language · Computer Science 2024-07-17 Yuanhe Tian , Ruyi Gan , Yan Song , Jiaxing Zhang , Yongdong Zhang

Small Language Models (SLMs) are becoming increasingly popular in specialized fields, such as industrial applications, due to their efficiency, lower computational requirements, and ability to be fine-tuned for domain-specific tasks,…

Computation and Language · Computer Science 2025-10-22 Shuxin Lin , Dhaval Patel , Christodoulos Constantinides

Large language models (LLMs) have shown great promise in the medical domain, achieving strong performance on several benchmarks. However, they continue to underperform in real-world medical scenarios, which often demand stronger…

Artificial Intelligence · Computer Science 2025-11-17 Yuxuan Zhou , Yubin Wang , Bin Wang , Chen Ning , Xien Liu , Ji Wu , Jianye Hao

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

There is an increasing interest in developing LLMs for medical diagnosis to improve diagnosis efficiency. Despite their alluring technological potential, there is no unified and comprehensive evaluation criterion, leading to the inability…

Computation and Language · Computer Science 2023-08-16 Xiaoming Shi , Jie Xu , Jinru Ding , Jiali Pang , Sichen Liu , Shuqing Luo , Xingwei Peng , Lu Lu , Haihong Yang , Mingtao Hu , Tong Ruan , Shaoting Zhang

Multimodal Large Language Models (MLLMs) have shown success in various general image processing tasks, yet their application in medical imaging is nascent, lacking tailored models. This study investigates the potential of MLLMs in improving…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Ling Yang , Zhanyu Wang , Zhenghao Chen , Xinyu Liang , Luping Zhou

Large language models (LLMs) have achieved strong performance on medical question answering (medical QA), and chain-of-thought (CoT) prompting has further improved results by eliciting explicit intermediate reasoning; meanwhile,…

Computation and Language · Computer Science 2026-04-03 Zaifu Zhan , Mengyuan Cui , Rui Zhang

Large Language Models (LLMs) have been showing promising results for various NLP-tasks without the explicit need to be trained for these tasks by using few-shot or zero-shot prompting techniques. A common NLP-task is question-answering…

Computation and Language · Computer Science 2024-12-18 Kevin Fischer , Darren Fürst , Sebastian Steindl , Jakob Lindner , Ulrich Schäfer

Large language models (LLMs) have been widely adopted in various downstream task domains. However, their abilities to directly recall and apply factual medical knowledge remains under-explored. Most existing medical QA benchmarks assess…

Computation and Language · Computer Science 2025-08-20 Jiaxi Li , Yiwei Wang , Kai Zhang , Yujun Cai , Bryan Hooi , Nanyun Peng , Kai-Wei Chang , Jin Lu

Clinical Question Answering (QA) systems enable doctors to quickly access patient information from electronic health records (EHRs). However, training these systems requires significant annotated data, which is limited due to the expertise…

Computation and Language · Computer Science 2024-12-09 Fan Bai , Keith Harrigian , Joel Stremmel , Hamid Hassanzadeh , Ardavan Saeedi , Mark Dredze

Explainable disease diagnosis, which leverages patient information (e.g., signs and symptoms) and computational models to generate probable diagnoses and reasonings, offers clear clinical values. However, when clinical notes encompass…

Practitioners deploying small open-weight large language models (LLMs) for medical question answering face a recurring design choice: invest in a domain-fine-tuned model, or keep a general-purpose model and inject domain knowledge at…

Computation and Language · Computer Science 2026-04-28 Avi-ad Avraam Buskila