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We introduce a unique semantic segmentation dataset of 6,096 high-resolution aerial images capturing indigenous and invasive grass species in Bega Valley, New South Wales, Australia, designed to address the underrepresented domain of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Sophia J. Abraham , Jin Huang , Brandon RichardWebster , Michael Milford , Jonathan D. Hauenstein , Walter Scheirer

Cellular image segmentation is essential for quantitative biology yet remains difficult due to heterogeneous modalities, morphological variability, and limited annotations. We present GenCellAgent, a training-free multi-agent framework that…

Quantitative Methods · Quantitative Biology 2026-05-12 Xi Yu , Yang Yang , Qun Liu , Yonghua Du , Sean McSweeney , Yuewei Lin

Integrating heterogeneous datasets across different measurement platforms is a fundamental challenge in many scientific applications. A common example arises in deconvolution problems, such as cell type deconvolution, where one aims to…

Methodology · Statistics 2025-09-30 Dongyue Xie , Lin Gui , Jingshu Wang

Quantitative Transmission Electron Microscopy (TEM) during in-situ straining experiment is able to reveal the motion of dislocations -- linear defects in the crystal lattice of metals. In the domain of materials science, the knowledge about…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Karina Ruzaeva , Kishan Govind , Marc Legros , Stefan Sandfeld

Extracting single-cell information from microscopy data requires accurate instance-wise segmentations. Obtaining pixel-wise segmentations from microscopy imagery remains a challenging task, especially with the added complexity of…

Computer Vision and Pattern Recognition · Computer Science 2024-01-02 Christoph Reich , Tim Prangemeier , André O. Françani , Heinz Koeppl

AI evaluation suites often report many scores without checking whether those scores carry independent information. We introduce Effective Dimensionality (ED), the participation ratio of a centered benchmark-score spectrum, as a fast,…

Artificial Intelligence · Computer Science 2026-04-01 Tommy Sha , Stella Zhao

Cell segmentation is a fundamental task in microscopy image analysis. Several foundation models for cell segmentation have been introduced, virtually all of them are extensions of Segment Anything Model (SAM), improving it for microscopy…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Anwai Archit , Constantin Pape

Neuron segmentation from electron microscopy (EM) volumes is crucial for understanding brain circuits, yet the complex neuronal structures in high-resolution EM images present significant challenges. EM data exhibits unique characteristics…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Yinda Chen , Haoyuan Shi , Xiaoyu Liu , Te Shi , Ruobing Zhang , Dong Liu , Zhiwei Xiong , Feng Wu

Although the U-Net architecture has been extensively used for segmentation of medical images, we address two of its shortcomings in this work. Firstly, the accuracy of vanilla U-Net degrades when the target regions for segmentation exhibit…

Multimodal Large Language Models (MLLMs) have achieved strong performance on general visual benchmarks but struggle with out-of-distribution (OOD) tasks in specialized domains such as medical imaging, where labeled data is limited and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Ci-Siang Lin , Min-Hung Chen , Yu-Yang Sheng , Yu-Chiang Frank Wang

Automatic detection and segmentation of objects in 2D and 3D microscopy data is important for countless biomedical applications. In the natural image domain, spatial embedding-based instance segmentation methods are known to yield…

Image and Video Processing · Electrical Eng. & Systems 2021-04-30 Manan Lalit , Pavel Tomancak , Florian Jug

Accurate segmentation of blood vessels is essential for various clinical assessments and postoperative analyses. However, the inherent challenges of vascular imaging, such as sparsity, fine granularity, low contrast, data distribution…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Dongning Song , Weijian Huang , Jiarun Liu , Md Jahidul Islam , Hao Yang , Shanshan Wang

Electroencephalography (EEG) reflects the brain's functional state, making it a crucial tool for diverse detection applications like seizure detection and sleep stage classification. While deep learning-based approaches have recently shown…

Machine Learning · Computer Science 2025-10-07 Kerui Wu , Ziyue Zhao , Bülent Yener

The objective in extreme multi-label learning is to train a classifier that can automatically tag a novel data point with the most relevant subset of labels from an extremely large label set. Embedding based approaches make training and…

Machine Learning · Computer Science 2015-07-13 Kush Bhatia , Himanshu Jain , Purushottam Kar , Prateek Jain , Manik Varma

In-vivo optical microscopy is advancing into routine clinical practice for non-invasively guiding diagnosis and treatment of cancer and other diseases, and thus beginning to reduce the need for traditional biopsy. However, reading and…

Image and Video Processing · Electrical Eng. & Systems 2020-01-07 Kivanc Kose , Alican Bozkurt , Christi Alessi-Fox , Melissa Gill , Caterina Longo , Giovanni Pellacani , Jennifer Dy , Dana H. Brooks , Milind Rajadhyaksha

Automated cell segmentation is crucial for various biological and medical applications, facilitating tasks like cell counting, morphology analysis, and drug discovery. However, manual segmentation is time-consuming and prone to…

Machine Learning · Computer Science 2024-09-13 Aaron Rock Menezes , Bharath Ramsundar

Unlabeled shape analysis is a rapidly emerging and challenging area of statistics. This has been driven by various novel applications in bioinformatics. We consider here the situation where two configurations are matched under various…

Applications · Statistics 2012-09-28 Kanti V. Mardia , Emma M. Petty , Charles C. Taylor

Continual learning (CL) is essential for deploying medical image segmentation models in clinical environments where imaging domains, anatomical targets, and diagnostic tasks evolve over time. However, continual segmentation still faces…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Bomin Wang , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

Electron microscopy (EM) enables the reconstruction of neural circuits at the level of individual synapses, which has been transformative for scientific discoveries. However, due to the complex morphology, an accurate reconstruction of…

The semantic segmentation of parts of objects in the wild is a challenging task in which multiple instances of objects and multiple parts within those objects must be detected in the scene. This problem remains nowadays very marginally…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Umberto Michieli , Edoardo Borsato , Luca Rossi , Pietro Zanuttigh