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Automatic medical image segmentation has wide applications for disease diagnosing. However, it is much more challenging than natural optical image segmentation due to the high-resolution of medical images and the corresponding huge…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Ziqiang Li , Rentuo Tao , Qianrun Wu , Bin Li

Large language models~(LLMs) are known for their high demand on computing resources and memory due to their substantial model size, which leads to inefficient inference on moderate GPU systems. Techniques like quantization or pruning can…

Computational Engineering, Finance, and Science · Computer Science 2024-11-26 Wenxiang Lin , Xinglin Pan , Shaohuai Shi , Xuan Wang , Xiaowen Chu

In computational pathology, whole-slide image (WSI) classification presents a formidable challenge due to its gigapixel resolution and limited fine-grained annotations. Multiple-instance learning (MIL) offers a weakly supervised solution,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Renao Yan , Qiehe Sun , Cheng Jin , Yiqing Liu , Yonghong He , Tian Guan , Hao Chen

Manually annotating nuclei from the gigapixel Hematoxylin and Eosin (H&E)-stained Whole Slide Images (WSIs) is a laborious and costly task, meaning automated algorithms for cell nuclei instance segmentation and classification could…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 João D. Nunes , Diana Montezuma , Domingos Oliveira , Tania Pereira , Jaime S. Cardoso

We tackle the challenge of efficiently reconstructing 3D scenes with high detail on objects of interest. Existing 3D Gaussian Splatting (3DGS) methods allocate resources uniformly across the scene, limiting fine detail to Regions Of…

Graphics · Computer Science 2025-10-20 Quoc-Anh Bui , Gilles Rougeron , Géraldine Morin , Simone Gasparini

Transformer-based models are becoming more and more intelligent and are revolutionizing a wide range of human tasks. To support their deployment, AI labs offer inference services that consume hundreds of GWh of energy annually and charge…

Systems and Control · Electrical Eng. & Systems 2025-08-29 Ching-Yi Lin , Sahil Shah

Full-parameter fine-tuning of large language models is constrained by substantial GPU memory requirements. Low-rank adaptation methods mitigate this challenge by updating only a subset of parameters. However, these approaches often limit…

Computation and Language · Computer Science 2026-04-10 Kaiyuan Tian , Yu Tang , Gongqingjian Jiang , Baihui Liu , Yifu Gao , Xialin Su , Linbo Qiao , Dongsheng Li

The complex regulatory dynamics of a biological network can be succinctly captured using discrete logic models. Given even sparse time-course data from the system of interest, previous work has shown that global optimization schemes are…

Molecular Networks · Quantitative Biology 2026-04-22 Joyce Reimer , Pranta Saha , Chris Chen , Neeraj Dhar , Brook Byrns , Steven Rayan , Gordon Broderick

Artificial Intelligence (AI) has great potential to improve health outcomes by training systems on vast digitized clinical datasets. Computational Pathology, with its massive amounts of microscopy image data and impact on diagnostics and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Gabriele Campanella , Eugene Fluder , Jennifer Zeng , Chad Vanderbilt , Thomas J. Fuchs

To handle the large scale of whole slide images in computational pathology, most approaches first tessellate the images into smaller patches, extract features from these patches, and finally aggregate the feature vectors with…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Benedikt Roth , Valentin Koch , Sophia J. Wagner , Julia A. Schnabel , Carsten Marr , Tingying Peng

In trained deep neural networks, unstructured pruning can reduce redundant weights to lower storage cost. However, it requires the customization of hardwares to speed up practical inference. Another trend accelerates sparse model inference…

Computer Vision and Pattern Recognition · Computer Science 2020-10-30 Zhuliang Yao , Shijie Cao , Wencong Xiao , Chen Zhang , Lanshun Nie

High-resolution images are prevalent in various applications, such as autonomous driving and computer-aided diagnosis. However, training neural networks on such images is computationally challenging and easily leads to out-of-memory errors…

Computer Vision and Pattern Recognition · Computer Science 2023-03-08 Benjamin Bergner , Christoph Lippert , Aravindh Mahendran

Referral workflow inefficiencies, including misaligned referrals and delays, contribute to suboptimal patient outcomes and higher healthcare costs. In this study, we investigated the possibility of predicting procedural needs based on…

Accurately classifying white blood cells from microscopic images is essential to identify several illnesses and conditions in medical diagnostics. Many deep learning technologies are being employed to quickly and automatically classify…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Tatwadarshi P. Nagarhalli , Shruti S. Pawar , Soham A. Dahanukar , Uday Aswalekar , Ashwini M. Save , Sanket D. Patil

The deep neural network is a research hotspot for histopathological image analysis, which can improve the efficiency and accuracy of diagnosis for pathologists or be used for disease screening. The whole slide pathological image can reach…

Image and Video Processing · Electrical Eng. & Systems 2022-05-09 Tingting Zheng , Weixing chen , Shuqin Li , Hao Quan , Qun Bai , Tianhang Nan , Song Zheng , Xinghua Gao , Yue Zhao , Xiaoyu Cui

Medical images such as 3D computerized tomography (CT) scans and pathology images, have hundreds of millions or billions of voxels/pixels. It is infeasible to train CNN models directly on such high resolution images, because neural…

Image and Video Processing · Electrical Eng. & Systems 2019-09-16 Le Hou , Youlong Cheng , Noam Shazeer , Niki Parmar , Yeqing Li , Panagiotis Korfiatis , Travis M. Drucker , Daniel J. Blezek , Xiaodan Song

The advancement of digital pathology, particularly through computational analysis of whole slide images (WSI), is poised to significantly enhance diagnostic precision and efficiency. However, the large size and complexity of WSIs make it…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Ravi Kant Gupta , Dadi Dharani , Shambhavi Shanker , Amit Sethi

Recent progress in Medical Artificial Intelligence (AI) has delivered systems that can reach clinical expert level performance. However, such systems tend to demonstrate sub-optimal "out-of-distribution" performance when evaluated in…

The condition of the Glomeruli, or filter sacks, in renal Direct Immunofluorescence (DIF) specimens is a critical indicator for diagnosing kidney diseases. A digital pathology system which digitizes a glass histology slide into a Whole…

Computer Vision and Pattern Recognition · Computer Science 2019-09-24 Can Peng , Kun Zhao , Arnold Wiliem , Teng Zhang , Peter Hobson , Anthony Jennings , Brian C. Lovell

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi
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