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Machine learning algorithms such as linear regression, SVM and neural network have played an increasingly important role in the process of scientific discovery. However, none of them is both interpretable and accurate on nonlinear datasets.…
Automated recognition of facial expressions of emotions, and detection of facial action units (AUs), from videos depends critically on modeling of their dynamics. These dynamics are characterized by changes in temporal phases…
Transcriptomic assays such as the PAM50-based ROR-P score guide recurrence risk stratification in non-metastatic, ER-positive, HER2-negative breast cancer but are not universally accessible. Histopathology is routinely available and may…
Many machine learning problems such as speech recognition, gesture recognition, and handwriting recognition are concerned with simultaneous segmentation and labeling of sequence data. Latent-dynamic conditional random field (LDCRF) is a…
This paper introduces a novel framework for image quality transfer based on conditional flow matching (CFM). Unlike conventional generative models that rely on iterative sampling or adversarial objectives, CFM learns a continuous flow…
Slot filling is a crucial component in task-oriented dialog systems that is used to parse (user) utterances into semantic concepts called slots. An ontology is defined by the collection of slots and the values that each slot can take. The…
Digital pathology tasks have benefited greatly from modern deep learning algorithms. However, their need for large quantities of annotated data has been identified as a key challenge. This need for data can be countered by using…
In modern scientific research, the objective is often to identify which variables are associated with an outcome among a large class of potential predictors. This goal can be achieved by selecting variables in a manner that controls the the…
Click-through rate(CTR) prediction is a core task in cost-per-click(CPC) advertising systems and has been studied extensively by machine learning practitioners. While many existing methods have been successfully deployed in practice, most…
Substantial progress has been made in identifying single genetic variants predisposing to common complex diseases. Nonetheless, the genetic etiology of human diseases remains largely unknown. Human complex diseases are likely influenced by…
We have proposed a novel method for Synthetic High Range Resolution (HRR) profiling, under the condition of missing frequency domain samples. This new approach estimates the autocovariance function (ACF) of the signal by valid sample pairs.…
We present an approach for the joint segmentation and grouping of similar components in anisotropic 3D image data and use it to segment neural tissue in serial sections electron microscopy (EM) images. We first construct a nested set of…
Motivation: Phenotype concept recognition (CR) is a fundamental task in biomedical text mining. However, existing methods either require ontology-specific training, making them struggle to generalize across diverse text styles and evolving…
Multi-rater medical image segmentation captures the inherent ambiguity of clinical interpretation, where diagnostic boundaries vary across experts and imaging devices. Existing approaches often reduce this diversity to consensus labels or…
Timely identification and accurate risk stratification of cardiovascular disease (CVD) remain essential for reducing global mortality. While existing prediction models primarily leverage structured data, unstructured clinical notes contain…
The automatic detection of critical findings in chest X-rays (CXR), such as pneumothorax, is important for assisting radiologists in their clinical workflow like triaging time-sensitive cases and screening for incidental findings. While…
Vision--language models (VLMs) for radiology report generation (RRG) can produce long-form chest CT reports from volumetric scans and show strong potential to improve radiology workflow efficiency and consistency. However, existing methods…
We propose a new method named the Conditional Randomization Rank Test (CRRT) for testing conditional independence of a response variable Y and a covariate variable X, conditional on the rest of the covariates Z. The new method generalizes…
Conformal prediction methodologies have significantly advanced the quantification of uncertainties in predictive models. Yet, the construction of confidence regions for model parameters presents a notable challenge, often necessitating…
Vision-language models (VLMs) can couple visual perception with open-ended clinical reasoning, making them attractive for computational histopathology. However, fine-tuning billions of parameters on scarce, expert-annotated pathology data…