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Large Language Models (LLMs) are increasingly deployed as reasoning systems, where reasoning paradigms - such as Chain-of-Thought (CoT) and multi-agent systems (MAS) - play a critical role, yet their relative effectiveness and cost-accuracy…

The rise of Large Language Models (LLMs) has driven progress in reasoning tasks -- from program synthesis to scientific hypothesis generation -- yet their ability to handle ranked preferences and structured algorithms in combinatorial…

Recent advances in Large Language Models (LLMs) have intensified the debate surrounding the fundamental nature of their reasoning capabilities. While achieving high performance on benchmarks such as GPQA and MMLU, these models exhibit…

Large Language Models (LLMs) have shown strong potential in complex medical reasoning yet face diminishing gains under inference scaling laws. While existing studies augment LLMs with various knowledge types, it remains unclear how…

The use of large language models either as decision support systems, or in agentic workflows, is rapidly transforming the digital ecosystem. However, the understanding of LLM decision-making under uncertainty remains limited. We study LLM…

Large language models (LLMs) have shown impressive capabilities, but still struggle with complex reasoning tasks requiring multiple steps. While prompt-based methods like Chain-of-Thought (CoT) can improve LLM reasoning at inference time,…

Large language models (LLMs) show potential for ophthalmic clinical reasoning, yet individual models risk introducing harm. We evaluated whether multi-agent LLM deliberative councils improve diagnostic performance and mitigate harm compared…

Large Language Models (LLMs) are increasingly utilized in AI-driven educational instruction and assessment, particularly within mathematics education. The capability of LLMs to generate accurate answers and detailed solutions for math…

The rising prevalence of eye diseases poses a growing public health burden. Large language models (LLMs) offer a promising path to reduce documentation workload and support clinical decision-making. However, few have been tailored for…

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

This study investigates the reasoning robustness of large language models (LLMs) on mathematical problem-solving tasks under systematically introduced input perturbations. Using the GSM8K dataset as a controlled testbed, we evaluate how…

Large language models (LLMs) have emerged as transformative tools in medicine, with strong capabilities in language understanding, reasoning, and structured information extraction. Radiation oncology is particularly well suited for LLM…

Large Language Models (LLMs) have significantly advanced natural language processing, demonstrating exceptional reasoning, tool usage, and memory capabilities. As their applications expand into multi-agent environments, there arises a need…

Large language models (LLMs) have recently shown remarkable performance in language tasks and beyond. However, due to their limited inherent causal reasoning ability, LLMs still face challenges in handling tasks that require robust causal…

A seminal paper published by Ledley and Lusted in 1959 introduced complex clinical diagnostic reasoning cases as the gold standard for the evaluation of expert medical computing systems, a standard that has held ever since. Here, we report…

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve…

We examine the reasoning and planning capabilities of large language models (LLMs) in solving complex tasks. Recent advances in inference-time techniques demonstrate the potential to enhance LLM reasoning without additional training by…

Recent advancements in reasoning-focused language models such as OpenAI's O1 and DeepSeek-R1 have shown that scaling test-time computation-through chain-of-thought reasoning and iterative exploration-can yield substantial improvements on…

DeepSeek-R1 is a cutting-edge open-source large language model (LLM) developed by DeepSeek, showcasing advanced reasoning capabilities through a hybrid architecture that integrates mixture of experts (MoE), chain of thought (CoT) reasoning,…

Large language models (LLMs) show promise for supporting clinical decision-making in complex fields such as rheumatology. Our evaluation shows that smaller language models (SLMs), combined with retrieval-augmented generation (RAG), achieve…