Related papers: Dose-LET Interactions Predict Capsular Contracture…
Purpose: Pencil beam scanning proton therapy is sensitive to respiratory motion, leading to potential dose inhomogeneities due to interplay effects. We developed and validated a predictive framework to assess interplay and motion robustness…
Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging techniques - a coded mask approach - both experimentally and via…
Prognostic evaluation in patients with colorectal liver metastases (CRLM) remains challenging due to suboptimal accuracy of conventional clinical models. This study developed and validated a robust machine learning model for predicting…
This work reports femtoscopic correlations of p$-$p ($\bar{\rm p}-\bar{\rm p}$) and p$-$d ($\bar{\rm p}-\bar{\rm d}$) pairs measured in Pb$-$Pb collisions at center-of-mass energy per nucleon $\sqrt{s_{\rm NN}}$ = 5.02 TeV in the ALICE…
Lung cancer has a high rate of recurrence in early-stage patients. Predicting the post-surgical recurrence in lung cancer patients has traditionally been approached using single modality information of genomics or radiology images. We…
Treatment planning is currently a patient specific, time-consuming, and resource demanding task in radiotherapy. Dose-volume histogram (DVH) prediction plays a critical role in automating this process. The geometric relationship between…
A survey was designed to inquire about the practice of proton SBRT treatment for prostate cancer. The survey was distributed to all 30 proton therapy centers in the United States that participate in the National Clinical Trial Network in…
Medical image registration and segmentation are two of the most frequent tasks in medical image analysis. As these tasks are complementary and correlated, it would be beneficial to apply them simultaneously in a joint manner. In this paper,…
Boron Neutron Capture Therapy (BNCT) is an innovative binary form of radiation therapy with high selectivity towards cancer tissue based on the neutron capture reaction 10B(n,$\alpha$)7Li, consisting in the exposition of patients to neutron…
Heavy ions have varying effects on the target. The most important factor in comparing this effect is Linear Energy Transfer (LET). Protons and carbons are heavy ions with high LET. Since these ions lose energy through collisions as they…
Very recently, for the first time, the two channels of nuclear deeply virtual Compton scattering (DVCS), the coherent and incoherent ones, have been separated by the CLAS collaboration at JLab, using a $^4$He target. The incoherent channel,…
Proton FLASH therapy leverages ultra-high dose-rate radiation to enhance the sparing of organs at risk without compromising tumor control probability. To prepare for the delivery of high doses to targets, we aim to develop a deep…
The longitudinal proton-proton femtoscopy (HBT) correlation function, based on the idea that in a heavy ion collision at $\sqrt{s} \lesssim 20$ GeV stopped protons are likely to be separated in configuration space, is evaluated. It shows a…
Results on two-particle angular correlations for charged particles emitted in proton-proton collisions at center-of-mass energies of 0.9, 2.36, and 7 TeV are presented, using data collected with the CMS detector over a broad range of…
Protontherapy is hadrontherapy fastest-growing modality and a pillar in the battle against cancer. Hadrontherapy superiority lies in its inverted depth-dose profile, hence tumour-confined irradiation. Protons, however, lack distinct…
Premature ventricular contraction(PVC) is a type of premature ectopic beat originating from the ventricles. Automatic method for accurate and robust detection of PVC is highly clinically desired.Currently, most of these methods are…
Background: Upright proton therapy with compact delivery systems has the potential to reduce costs for treatments but could also lead to broadening of the beam penumbra due to energy selection close to the patient. Purpose: This study aims…
Purpose: To present a methodology to analyze the variation of RBE with fractionation from clinical data of tumor control probability (TCP) and to apply it to study the response of prostate cancer to proton therapy. M&M: We analyzed the…
Proton computed tomography (pCT) aims to facilitate precise dose planning for hadron therapy, a promising and effective method for cancer treatment. Hadron therapy utilizes protons and heavy ions to deliver well focused doses of radiation,…
Introduction: Lung cancer is a leading cause of cancer-related mortality, and stereotactic body radiotherapy (SBRT) has become a standard treatment for early-stage lung cancer. However, the heterogeneous response to radiation at the tumor…