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Knowledge graphs (KGs) such as DBpedia, Freebase, YAGO, Wikidata, and NELL were constructed to store large-scale, real-world facts as (subject, predicate, object) triples -- that can also be modeled as a graph, where a node (a subject or an…

Databases · Computer Science 2023-05-25 Arijit Khan

In recent years, AI models that mine intrinsic patterns from molecular structures and protein sequences have shown promise in accelerating drug discovery. However, these methods partly lag behind real-world pharmaceutical approaches of…

Machine Learning · Computer Science 2023-10-17 Yizhen Luo , Xing Yi Liu , Kai Yang , Kui Huang , Massimo Hong , Jiahuan Zhang , Yushuai Wu , Zaiqing Nie

Knowledge Graphs (KGs) have emerged as invaluable resources for enriching recommendation systems by providing a wealth of factual information and capturing semantic relationships among items. Leveraging KGs can significantly enhance…

Information Retrieval · Computer Science 2023-12-29 Yangqin Jiang , Yuhao Yang , Lianghao Xia , Chao Huang

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…

Machine Learning · Computer Science 2025-02-25 Ziwei Yang , Zheng Chen , Xin Liu , Rikuto Kotoge , Peng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

Domain experts often rely on most recent knowledge for apprehending and disseminating specific biological processes that help them design strategies for developing prevention and therapeutic decision-making in various disease scenarios. A…

Computation and Language · Computer Science 2023-11-21 Md. Rezaul Karim , Lina Molinas Comet , Md Shajalal , Oya Deniz Beyan , Dietrich Rebholz-Schuhmann , Stefan Decker

Medical tasks such as diagnosis and treatment planning require precise and complex reasoning, particularly in life-critical domains. Unlike mathematical reasoning, medical reasoning demands meticulous, verifiable thought processes to ensure…

Computation and Language · Computer Science 2025-04-08 Juncheng Wu , Wenlong Deng , Xingxuan Li , Sheng Liu , Taomian Mi , Yifan Peng , Ziyang Xu , Yi Liu , Hyunjin Cho , Chang-In Choi , Yihan Cao , Hui Ren , Xiang Li , Xiaoxiao Li , Yuyin Zhou

Deep learning has brought significant progress to medical image classification, yet most existing methods still rely on isolated visual evidence and cannot effectively leverage similar cases or external knowledge. In clinical practice,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Yiming Xu , Yixuan Liu , Yuhang Zhang , Ling Zheng , Yihan Wang , Qi Song

Knowledge Graph-based Question Answering (KGQA) plays a pivotal role in complex reasoning tasks but remains constrained by two persistent challenges: the structural heterogeneity of Knowledge Graphs(KGs) often leads to semantic mismatch…

Computation and Language · Computer Science 2026-05-19 Peng Yu , En Xu , Bin Chen , Haibiao Chen , Yinfei Xu

Knowledge Graph (KG) completion research usually focuses on densely connected benchmark datasets that are not representative of real KGs. We curate two KG datasets that include biomedical and encyclopedic knowledge and use an existing…

Machine Learning · Computer Science 2021-06-15 Justin Lovelace , Denis Newman-Griffis , Shikhar Vashishth , Jill Fain Lehman , Carolyn Penstein Rosé

Domain-specific knowledge graphs (DKGs) are critical yet often suffer from limited coverage compared to General Knowledge Graphs (GKGs). Existing tasks to enrich DKGs rely primarily on extracting knowledge from external unstructured data or…

Artificial Intelligence · Computer Science 2026-02-16 Runhao Zhao , Weixin Zeng , Wentao Zhang , Chong Chen , Zhengpin Li , Xiang Zhao , Lei Chen

Medical reasoning models remain constrained by parametric knowledge and are thus susceptible to forgetting and hallucinations. DeepResearch (DR) models ground outputs in verifiable evidence from tools and perform strongly in general…

Artificial Intelligence · Computer Science 2026-02-05 Zihan Wang , Hao Wang , Shi Feng , Xiaocui Yang , Daling Wang , Yiqun Zhang , Jinghao Lin , Haihua Yang , Xiaozhong Ji

Biomedical knowledge graphs (KGs) are widely used in the life sciences, yet many are derived from unstructured documents and therefore lack schema-level constrains, whereas graphs assembled from structured resources are difficult to…

Artificial Intelligence · Computer Science 2026-05-01 Lucas Vittor , Ayush Noori , Iñaki Arango , Joaquín Polonuer , Sam Rodriques , Andrew White , David A. Clifton , Marinka Zitnik

Medical report generation, which aims to automatically generate a long and coherent report of a given medical image, has been receiving growing research interests. Existing approaches mainly adopt a supervised manner and heavily rely on…

Machine Learning · Computer Science 2021-11-16 Fenglin Liu , Chenyu You , Xian Wu , Shen Ge , Sheng Wang , Xu Sun

Answering complex logical queries on large-scale incomplete knowledge graphs (KGs) is a fundamental yet challenging task. Recently, a promising approach to this problem has been to embed KG entities as well as the query into a vector space…

Machine Learning · Computer Science 2020-03-03 Hongyu Ren , Weihua Hu , Jure Leskovec

Knowledge graphs (KGs) play a crucial role in many applications, such as question answering, but incompleteness is an urgent issue for their broad application. Much research in knowledge graph completion (KGC) has been performed to resolve…

Artificial Intelligence · Computer Science 2023-01-10 Yinyu Lan , Shizhu He , Kang Liu , Jun Zhao

Modern distributed decision-making systems face significant challenges arising from data heterogeneity, dynamic environments, and the need for decentralized coordination. This paper introduces the Knowledge Sharing paradigm as an innovative…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-10 Rosario Napoli , Gabriele Morabito , Antonio Celesti , Massimo Villari , Maria Fazio

The exponential growth of scientific knowledge has created significant barriers to cross-disciplinary knowledge discovery, synthesis and research collaboration. In response to this challenge, we present BioSage, a novel compound AI…

In recent years, we have witnessed the proliferation of knowledge graphs (KG) in various domains, aiming to support applications like question answering, recommendations, etc. A frequent task when integrating knowledge from different KGs is…

Databases · Computer Science 2023-06-08 Nikolaos Fanourakis , Vasilis Efthymiou , Dimitris Kotzinos , Vassilis Christophides

Deep neural networks (DNNs) remain largely opaque at inference time, limiting our ability to detect and diagnose malicious input manipulations such as adversarial examples. Existing detection methods predominantly rely on layer-local…

Cryptography and Security · Computer Science 2026-04-17 Firas Ben Hmida , Philemon Hailemariam , Kashif Ali Khan , Birhanu Eshete
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