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Background: Simulated patient systems are important in medical education and research, providing safe, integrative training environments and supporting clinical decision making. Advances in artificial intelligence (AI), especially large…

Training medical personnel using standardized patients (SPs) remains a complex challenge, requiring extensive domain expertise and role-specific practice. Previous research on Large Language Model (LLM)-based SPs mostly focuses on improving…

Computation and Language · Computer Science 2025-06-10 Zhuoyun Du , Lujie Zheng , Renjun Hu , Yuyang Xu , Xiawei Li , Ying Sun , Wei Chen , Jian Wu , Haolei Cai , Haohao Ying

Recent advances in large language models (LLMs) have accelerated the development of conversational agents capable of generating human-like responses. Since psychiatric assessments typically involve complex conversational interactions…

Computation and Language · Computer Science 2025-01-06 Jingoo Lee , Kyungho Lim , Young-Chul Jung , Byung-Hoon Kim

Creating effective dialogue systems for mental health support requires high-quality multi-turn counseling dialogue data, yet collecting real counselor-client conversations presents significant challenges, including privacy concerns, high…

Computation and Language · Computer Science 2026-05-27 Huachuan Qiu , Zhenzhong Lan

The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

Computation and Language · Computer Science 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

The development of chatbots requires collecting a large number of human-chatbot dialogues to reflect the breadth of users' sociodemographic backgrounds and conversational goals. However, the resource requirements to conduct the respective…

Computation and Language · Computer Science 2024-10-15 Hovhannes Tamoyan , Hendrik Schuff , Iryna Gurevych

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing conversations and providing emotional support as separate research directions. However, there remains a significant research gap in combining these…

Computation and Language · Computer Science 2025-08-11 Lanlan Qiu , Xiao Pu , Yeqi Feng , Tianxing He

Effective patient communication is pivotal in healthcare, yet traditional medical training often lacks exposure to diverse, challenging interpersonal dynamics. To bridge this gap, this study proposes the use of Large Language Models (LLMs)…

The clinical diagnosis of most mental disorders primarily relies on the conversations between psychiatrist and patient. The creation of such diagnostic conversation datasets is promising to boost the AI mental healthcare community. However,…

Computation and Language · Computer Science 2024-12-30 Congchi Yin , Feng Li , Shu Zhang , Zike Wang , Jun Shao , Piji Li , Jianhua Chen , Xun Jiang

Integrating large language models (LLMs) into healthcare holds great potential but faces challenges. Pre-training LLMs from scratch for domains like medicine is resource-heavy and often unfeasible. On the other hand, sole reliance on…

Computation and Language · Computer Science 2024-04-18 Qichen Ye , Junling Liu , Dading Chong , Peilin Zhou , Yining Hua , Fenglin Liu , Meng Cao , Ziming Wang , Xuxin Cheng , Zhu Lei , Zhenhua Guo

Large language models (LLMs) increasingly serve as interactive social agents, yet their ability to maintain coherent and authentic persona-level role-playing remains limited, particularly in realistic social scenarios. Existing research…

Artificial Intelligence · Computer Science 2026-05-19 Wenlong Shi , Jianxun Lian , Mingqi Wu , Haiming Qin , Mingyang Zhou , Xing Xie , Naipeng Chao , Hao Liao

Recently, the increasing demand for superior medical services has highlighted the discrepancies in the medical infrastructure. With big data, especially texts, forming the foundation of medical services, there is an exigent need for…

Computation and Language · Computer Science 2024-07-17 Yuanhe Tian , Ruyi Gan , Yan Song , Jiaxing Zhang , Yongdong Zhang

Large Language Models (LLMs) are increasingly demonstrating the potential to reach human-level performance in generating clinical summaries from patient-clinician conversations. However, these summaries often focus on patients' biology…

The advent of Large Language Models (LLMs) has paved the way for complex tasks such as role-playing, which enhances user interactions by enabling models to imitate various characters. However, the closed-source nature of state-of-the-art…

Large language models are increasingly deployed in multi-turn settings such as tutoring, support, and counseling, where reliability depends on preserving consistent roles, personas, and goals across long horizons. This requirement becomes…

Computation and Language · Computer Science 2026-04-13 Han Luo , Guy Laban

Mental illness remains one of the most critical public health issues. Despite its importance, many mental health professionals highlight a disconnect between their training and actual real-world patient practice. To help bridge this gap, we…

Large Language Models (LLMs) have demonstrated promising potential in providing empathetic support during interactions. However, their responses often become verbose or overly formulaic, failing to adequately address the diverse emotional…

Computation and Language · Computer Science 2024-12-12 Jing Ye , Lu Xiang , Yaping Zhang , Chengqing Zong

Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…

Artificial Intelligence · Computer Science 2025-03-24 Zhoujian Sun , Ziyi Liu , Cheng Luo , Jiebin Chu , Zhengxing Huang

Background: We present a Patient Simulator that leverages real world patient encounters which cover a broad range of conditions and symptoms to provide synthetic test subjects for development and testing of healthcare agentic models. The…

Computation and Language · Computer Science 2025-06-05 Sina Rashidian , Nan Li , Jonathan Amar , Jong Ha Lee , Sam Pugh , Eric Yang , Geoff Masterson , Myoung Cha , Yugang Jia , Akhil Vaid

Simulations constitute a fundamental component of medical and nursing education and traditionally employ standardized patients (SP) and high-fidelity manikins to develop clinical reasoning and communication skills. However, these methods…

Human-Computer Interaction · Computer Science 2025-10-23 Akilan Amithasagaran , Sagnik Dakshit , Bhavani Suryadevara , Lindsey Stockton