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Mental health assessment is crucial for early intervention and effective treatment, yet traditional clinician-based approaches are limited by the shortage of qualified professionals. Recent advances in artificial intelligence have sparked…

Computation and Language · Computer Science 2025-08-18 Jinpeng Hu , Ao Wang , Qianqian Xie , Hui Ma , Zhuo Li , Dan Guo

The application of AI in psychiatric diagnosis faces significant challenges, including the subjective nature of mental health assessments, symptom overlap across disorders, and privacy constraints limiting data availability. To address…

Social and Information Networks · Computer Science 2025-10-14 Mengxi Xiao , Ben Liu , He Li , Jimin Huang , Qianqian Xie , Xiaofen Zong , Mang Ye , Min Peng

An effective healthcare agent must be able to recall and reason over a patient's longitudinal medical history. However, the absence of datasets with realistic long-term dialogue timelines limits systematic evaluation. Real clinical text is…

Computation and Language · Computer Science 2026-05-20 Hebin Hu , Renke Dai , Ah-Hwee Tan , Yilin Kang

Retrieval-augmented generation (RAG) systems improve large language model outputs by incorporating external knowledge, enabling more informed and context-aware responses. However, the effectiveness and trustworthiness of these systems…

Computation and Language · Computer Science 2025-08-27 Ilias Driouich , Hongliu Cao , Eoin Thomas

Speech synthesis is crucial for human-computer interaction, enabling natural and intuitive communication. However, existing datasets involve high construction costs due to manual annotation and suffer from limited character diversity,…

Computation and Language · Computer Science 2025-04-22 Xiang Li , Duyi Pan , Hongru Xiao , Jiale Han , Jing Tang , Jiabao Ma , Wei Wang , Bo Cheng

Synthetic data is increasingly critical for contact centers, where privacy constraints and data scarcity limit the availability of real conversations. However, generating synthetic dialogues that are realistic and useful for downstream…

Computation and Language · Computer Science 2026-02-17 Rishikesh Devanathan , Varun Nathan , Ayush Kumar

Large Language Models (LLMs) offer promising opportunities to support mental healthcare workflows, yet they often lack the structured clinical reasoning needed for reliable diagnosis and may struggle to provide the emotionally attuned…

Artificial Intelligence · Computer Science 2026-04-20 Yuqi Wu , Guangya Wan , Jingjing Li , Shengming Zhao , Lingfeng Ma , Tianyi Ye , Ion Pop , Yanbo Zhang , Jie Chen

Single-agent large language model (LLM) systems struggle to simultaneously support diverse conversational functions and maintain safety in behavioral health communication. We propose a safety-aware, role-orchestrated multi-agent LLM…

Artificial Intelligence · Computer Science 2026-04-02 Ha Na Cho

The rapid spread of misinformation in the digital era poses significant challenges to public discourse, necessitating robust and scalable fact-checking solutions. Traditional human-led fact-checking methods, while credible, struggle with…

Artificial Intelligence · Computer Science 2025-06-24 Tam Trinh , Manh Nguyen , Truong-Son Hy

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

Human-Computer Interaction · Computer Science 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

Patient simulation is essential for developing and evaluating mental health dialogue systems. As most existing approaches rely on snapshot-style prompts with limited profile information, homogeneous behaviors and incoherent disease…

Computation and Language · Computer Science 2026-03-25 Baihan Li , Bingrui Jin , Kunyao Lan , Ming Wang , Mengyue Wu

Synthetic data generation with Large Language Models (LLMs) has emerged as a promising solution in the medical domain to mitigate data scarcity and privacy constraints. However, existing approaches remain constrained by their derivative…

Artificial Intelligence · Computer Science 2026-01-07 Yunghwei Lai , Ziyue Wang , Weizhi Ma , Yang Liu

Background: Cognitive biases in clinical decision-making significantly contribute to errors in diagnosis and suboptimal patient outcomes. Addressing these biases presents a formidable challenge in the medical field. Objective: This study…

Computation and Language · Computer Science 2024-05-14 Yu He Ke , Rui Yang , Sui An Lie , Taylor Xin Yi Lim , Hairil Rizal Abdullah , Daniel Shu Wei Ting , Nan Liu

Simulating high-fidelity patients offers a powerful avenue for studying complex diseases while addressing the challenges of fragmented, biased, and privacy-restricted real-world data. In this study, we introduce SynthAgent, a novel…

Artificial Intelligence · Computer Science 2026-02-10 Arman Aghaee , Sepehr Asgarian , Jouhyun Jeon

Psychiatric comorbidity is clinically significant yet challenging due to the complexity of multiple co-occurring disorders. To address this, we develop a novel approach integrating synthetic patient electronic medical record (EMR)…

Artificial Intelligence · Computer Science 2026-02-24 Tianxi Wan , Jiaming Luo , Siyuan Chen , Kunyao Lan , Jianhua Chen , Haiyang Geng , Mengyue Wu

Recent advances in large language models (LLMs) have accelerated the development of conversational agents capable of generating human-like responses. Since psychiatric assessments typically involve complex conversational interactions…

Computation and Language · Computer Science 2025-01-06 Jingoo Lee , Kyungho Lim , Young-Chul Jung , Byung-Hoon Kim

Access to electronic health records (EHRs) for digital health research is often limited by privacy regulations and institutional barriers. Synthetic EHRs have been proposed as a way to enable safe and sovereign data sharing; however,…

Machine Learning · Computer Science 2026-03-10 Guanglin Zhou , Armin Catic , Motahare Shabestari , Matthew Young , Chaiquan Li , Katrina Poppe , Sebastiano Barbieri

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a…

The clinical diagnosis of most mental disorders primarily relies on the conversations between psychiatrist and patient. The creation of such diagnostic conversation datasets is promising to boost the AI mental healthcare community. However,…

Computation and Language · Computer Science 2024-12-30 Congchi Yin , Feng Li , Shu Zhang , Zike Wang , Jun Shao , Piji Li , Jianhua Chen , Xun Jiang

We present an end-to-end framework for generating synthetic users for evaluating interactive agents designed to encourage positive behavior changes, such as in health and lifestyle coaching. The synthetic users are grounded in health and…

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