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Network models are widely used as structural summaries of biochemical systems. Statistical estimation of networks is usually based on linear or discrete models. However, the dynamics of these systems are generally nonlinear, suggesting that…

Applications · Statistics 2014-06-03 C. J. Oates , F. Dondelinger , N. Bayani , J. Korola , J. W. Gray , S. Mukherjee

In a recent paper it was shown that, for chemical reaction networks possessing a subtle structural property called concordance, dynamical behavior of a very circumscribed (and largely stable) kind is enforced, so long as the kinetics lies…

Molecular Networks · Quantitative Biology 2012-04-26 Guy Shinar , Martin Feinberg

We consider a system of two stochastic differential equations (SDEs) with competing two-way interactions driven by Brownian motions and spectrally positive $\alpha$-stable random measures. Such a SDE system can be identified as a…

Probability · Mathematics 2026-03-09 Jie Xiong , Xu Yang , Xiaowen Zhou

We investigate the possibility that for any given reaction rate vector $k$ associated with a network $G$, there exists another network $G'$ with a corresponding reaction rate vector that reproduces the mass-action dynamics generated by…

Dynamical Systems · Mathematics 2024-09-10 Samay Kothari , Jiaxin Jin , Abhishek Deshpande

A simple model of biological extinction with variable system size is presented that exhibits a power-law distribution of extinction event sizes. The model is a generalization of a model recently introduced by Newman (Proc. R. Soc. Lond.…

Biological Physics · Physics 2016-09-08 C. Wilke , T. Martinetz

We investigate an extremal dynamics model of evolution with a variable number of units. Due to addition and removal of the units, the topology of the network evolves and the network splits into several clusters. The activity is mostly…

Statistical Mechanics · Physics 2009-10-31 Frantisek Slanina , Miroslav Kotrla

We study the biodiversity problem for resource competition systems with extinctions and self-limitation effects. Our main result establishes estimates of biodiversity in terms of the fundamental parameters of the model. We also prove the…

Dynamical Systems · Mathematics 2018-09-12 Vladimir Kozlov , Sergey Vakulenko , Uno Wennergren , Vladimir G. Tkachev

Many mathematical models for biological phenomena, such as the spread of diseases, are based on reaction-diffusion equations for densities of interacting cell populations. We present a consistent derivation of reaction-diffusion equations…

Analysis of PDEs · Mathematics 2026-02-23 Marzia Bisi , Davide Cusseddu , Ana Jacinta Soares , Romina Travaglini

Analyzing coexistence and survival scenarios of Lotka-Volterra (LV) networks in which the total biomass is conserved is of vital importance for the characterization of long-term dynamics of ecological communities. Here, we introduce a…

Populations and Evolution · Quantitative Biology 2013-04-26 Johannes Knebel , Torben Krüger , Markus F. Weber , Erwin Frey

The dynamics of stochastic reaction networks within cells are inevitably modulated by factors considered extrinsic to the network such as for instance the fluctuations in ribsome copy numbers for a gene regulatory network. While several…

Quantitative Methods · Quantitative Biology 2015-06-19 Christoph Zechner , Heinz Koeppl

Relativistic energy density functionals have become a standard framework for nuclear structure studies of ground-state properties and collective excitations over the entire nuclide chart. We review recent developments in modeling nuclear…

Nuclear Theory · Physics 2015-10-28 N. Paar , T. Marketin , D. Vale , D. Vretenar

In this paper we consider a porous-elastic system consisting of nonlinear boundary/interior damping and nonlinear boundary/interior sources. Our interest lies in the theoretical understanding of the existence, finite time blow-up of…

Analysis of PDEs · Mathematics 2018-08-01 Vo Anh Khoa , Le Thi Phuong Ngoc , Nguyen Thanh Long

We investigate the contact process on scale-free networks evolving by a stationary dynamics whereby each vertex independently updates its connections with a rate depending on its power. This rate can be slowed down or speeded up by virtue…

Probability · Mathematics 2024-09-18 Emmanuel Jacob , Amitai Linker , Peter Mörters

The so-called Fundamental Theorem of Dynamical Systems -- which(1) relates attractors and repellers to the chain recurrent set and (2) gives the existence of a complete Lyapunov function -- can be seen as a means of separating out…

Dynamical Systems · Mathematics 2025-08-15 Andrew D. Lewis

We consider the chemical reaction networks and study currents in these systems. Reviewing recent decomposition of rate functionals from large deviation theory for Markov processes, we adapt these results for reaction networks. In…

Mathematical Physics · Physics 2019-12-16 Johannes Zimmer , D. R. Michiel Renger

We study the multi-species replicator model with linear fitness and random fitness matrices of various classes. By means of numerical resolution of the replicator equations, we determine the survival probability of a species in terms of its…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Sebastian Bouzat , Damian Zanette

In living cells, chemical reactions form a complex network. Complicated dynamics arising from such networks are the origins of biological functions. We propose a novel mathematical method to analyze bifurcation behaviors of a reaction…

Molecular Networks · Quantitative Biology 2018-08-08 Takashi Okada , Je-Chiang Tsai , Atsushi Mochizuki

We analyze purely competitive many-species Lotka-Volterra systems with random interaction matrices, focusing the attention on statistical properties of their asymptotic states. Generic features of the evolution are outlined from a…

adap-org · Physics 2009-10-30 Guillermo Abramson , Damian Zanette

The fundamental decomposition of a chemical reaction network (also called its "$\mathscr{F}$-decomposition") is the set of subnetworks generated by the partition of its set of reactions into the "fundamental classes" introduced by Ji and…

Dynamical Systems · Mathematics 2020-02-19 Bryan S. Hernandez , Eduardo R. Mendoza , Aurelio A. de los Reyes

Some populations, such as red blood cells (RBCs), exhibit a pattern of population decline that is closer to linear rather than exponential, which has proven to be unexpectedly challenging to describe with a single simple mathematical model.…

Populations and Evolution · Quantitative Biology 2020-04-14 Irina Kareva , Georgy Karev