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The phenomenon of hysteresis is commonly observed in many UV thermal experiments involving unmodified or modified nucleic acids. In presence of hysteresis, the thermal curves are irreversible and demand a significant effort to produce the…

The goal of hyperparameter tuning (or hyperparameter optimization) is to optimize the hyperparameters to improve the performance of the machine or deep learning model. spotPython (``Sequential Parameter Optimization Toolbox in Python'') is…

Machine Learning · Computer Science 2023-06-08 Thomas Bartz-Beielstein

Although the Harrow-Hassidim-Lloyd (HHL) algorithm offers an exponential speedup in system size for treating linear equations of the form $A\vec{x}=\vec{b}$ on quantum computers when compared to their traditional counterparts, it faces a…

It is highly desirable to borrow information from external data to augment a control arm in a randomized clinical trial, especially in settings where the sample size for the control arm is limited. However, a main challenge in borrowing…

Methodology · Statistics 2023-11-01 Dehua Bi , Tianjian Zhou , Wei Zhong , Yuan Ji

Adaptive methods for derivation of analytical and numerical solutions of heat diffusion in one dimensional thin rod have investigated. Comperhensive comparsion analysis based on the homotopy perturbation method (HPM) and finite difference…

Computational Physics · Physics 2018-07-26 Mehran Makhtoumi

Computing accurate periodic responses in strongly nonlinear or even non-smooth vibration systems remains a fundamental challenge in nonlinear dynamics. Existing numerical methods, such as the Harmonic Balance Method (HBM) and the Shooting…

Numerical Analysis · Mathematics 2025-10-28 Limin Cao , Yanmao Chen , Li Wang , Loic Salles , Zechang Zheng

Solving linear systems of equations plays a fundamental role in numerous computational problems from different fields of science. The widespread use of numerical methods to solve these systems motivates investigating the feasibility of…

We study Hibridizable Discontinuous Galerkin (HDG) discretizations for a class of non-linear interior elliptic boundary value problems posed in curved domains where both the source term and the diffusion coefficient are non-linear. We…

Numerical Analysis · Mathematics 2021-12-30 Nestor Sánchez , Tonatiuh Sánchez-Vizuet , Manuel E. Solano

Type 1 diabetes (T1D) management can be significantly enhanced through the use of predictive machine learning (ML) algorithms, which can mitigate the risk of adverse events like hypoglycemia. Hypoglycemia, characterized by blood glucose…

Quantitative Methods · Quantitative Biology 2025-04-02 Beyza Cinar , Jennifer Daniel Onwuchekwa , Maria Maleshkova

In this paper we established the condition for a curve to satisfy stochas- tic fractional HP (Hamilton-Pontryagin) equations. These equations are described using It^o integral. We have also considered the case of stochastic fractional…

Differential Geometry · Mathematics 2009-06-25 Chis Oana , Opris Dumitru

The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the HPA axis are correlated with many stress-related diseases such as post-traumatic…

Neurons and Cognition · Quantitative Biology 2016-04-20 Lae Un Kim , Maria R. D'Orsogna , Tom Chou

Hierarchical Temporal Memory (HTM) is a biomimetic machine learning algorithm imbibing the structural and algorithmic properties of the neocortex. Two main functional components of HTM that enable spatio-temporal processing are the spatial…

Hardware Architecture · Computer Science 2016-11-10 Lennard Streat , Dhireesha Kudithipudi , Kevin Gomez

In this paper, Optimal Homotopy Perturbation Method (OHPM) is employed to determine an analytic approximate solutions for nonlinear MHD Jeffery-Hamel flow and heat transfer problem. The Navier-Stokes equations, taking into account Maxwell's…

Numerical Analysis · Mathematics 2015-07-13 Vasile Marinca , Remus-Daniel Ene

Linear solvers are major computational bottlenecks in a wide range of decision support and optimization computations. The challenges become even more pronounced on heterogeneous hardware, where traditional sparse numerical linear algebra…

Computational Engineering, Finance, and Science · Computer Science 2024-01-26 Kasia Świrydowicz , Nicholson Koukpaizan , Maksudul Alam , Shaked Regev , Michael Saunders , Slaven Peleš

Hypertensive retinopathy (HR) is a severe eye disease that may cause permanent vision loss if not diagnosed early. Traditional diagnostic methods are time-consuming and subjective, highlighting the need for an automated, reliable system.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Suleyman Burcin Suyun , Mustafa Yurdakul , Sakir Tasdemir , Serkan Bilic

Hyperspectral (HS) imaging presents itself as a non-contact, non-ionizing and non-invasive technique, proven to be suitable for medical diagnosis. However, the volume of information contained in these images makes difficult providing the…

We present the Physics-Informed Optimal Homotopy Analysis Method (PI-OHAM) for solving nonlinear differential equations. PI-OHAM, based on classical HAM, employs a physics-informed residual loss to optimize convergence-control parameters…

Computational Engineering, Finance, and Science · Computer Science 2026-01-15 Ziya Uddin

We develop a prediction-based prescriptive model for learning optimal personalized treatments for patients based on their Electronic Health Records (EHRs). Our approach consists of: (i) predicting future outcomes under each possible therapy…

Machine Learning · Statistics 2018-12-06 Ruidi Chen , Ioannis Paschalidis

Hamiltonian simulation is one of the most promising candidates for the demonstration of quantum advantage within the next ten years, and several studies have proposed end-to-end resource estimates for executing such algorithms on…

Quantum Physics · Physics 2025-06-11 Tyler LeBlond , Ryan S. Bennink

Quadratic eigenvalue problems (QEP) and more generally polynomial eigenvalue problems (PEP) are among the most common types of nonlinear eigenvalue problems. Both problems, especially the QEP, have extensive applications. A typical approach…

Numerical Analysis · Mathematics 2017-11-07 Yiling You , Jose Israel Rodriguez , Lek-Heng Lim