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Derivative-free optimization methods are numerical methods for optimization problems in which no derivative information is used. Such optimization problems are widely seen in many real applications. One particular class of derivative-free…
Hyperbolic Programming (HP) --minimizing a linear functional over an affine subspace of a finite-dimensional real vector space intersected with the so-called hyperbolicity cone-- is a class of convex optimization problems that contains…
Diffusion models have demonstrated significant applications in the field of image generation. However, their high computational and memory costs pose challenges for deployment. Model quantization has emerged as a promising solution to…
We propose a new method for constructing rational spatial Pythagorean Hodograph (PH) curves based on determining a suitable rational framing motion. While the spherical component of the framing motion is arbitrary, the translation part is…
Using a residuum approach, we provide a complete description of the space of the rational spatial curves of given tangent directions. The rational Pythagorean hodograph curves are obtained as a special case when the norm of the direction…
In this paper, we explore using the Harrow-Hassidim-Lloyd (HHL) algorithm to address scientific and engineering problems through quantum computing, utilizing the NWQSim simulation package on a high-performance computing platform. Focusing…
Purpose: Thyroid scintigraphy plays a vital role in diagnosing a range of thyroid disorders. While deep learning classification models hold significant promise in this domain, their effectiveness is frequently compromised by limited and…
Many problems plague empirical Phillips curves (PCs). Among them is the hurdle that the two key components, inflation expectations and the output gap, are both unobserved. Traditional remedies include proxying for the absentees or…
Motivated by a practical need for the comparison of hemolysis curves at various treatment levels, we propose a novel method for pairwise comparison of mean functional responses. The hemolysis curves - the percent hemolysis as a function of…
High-intensity focused ultrasound (HIFU) is a promising treatment modality for the non-invasive ablation of pathogenic tissue in many organs. Optimal treatment planning strategies based on high-performance computing methods are expected to…
Network meta-analysis (NMA) is an extension of pairwise meta-analysis which facilitates the estimation of relative effects for multiple competing treatments. A hierarchy of treatments is a useful output of an NMA. Treatment hierarchies are…
To approximate solutions of complex nonlinear partial differential equations remains a computational challenge, especially for sets of equations relevant in industry, such as Euler or Navier-Stokes equations. Even the most sophisticated…
Background: trials to identify the minimal effective treatment duration are needed in different therapeutic areas, including bacterial infections, TB and Hepatitis--C. However, standard non-inferiority designs have several limitations,…
The Homotopy Perturbation Method (HPM) is used to solve the Burgers-Huxley non-linear differential equations. Three case study problems of Burgers-Huxley are solved using the HPM and the exact solutions are obtained. The rapid convergence…
The Harrow-Hassidim-Lloyd (HHL) algorithm is a quantum algorithm for solving systems of linear equations that, in principle, offers an exponential improvement in scaling with the system size compared to classical approaches. In this work,…
Thyroid cancer is the most common endocrine malignancy, and accurately distinguishing between benign and malignant thyroid tumors is crucial for developing effective treatment plans in clinical practice. Pathologically, thyroid tumors pose…
We propose an iterative improvement method for the Harrow-Hassidim-Lloyd (HHL) algorithm to solve a linear system of equations. This is a quantum-classical hybrid algorithm. The accuracy is essential to solve the linear system of equations.…
This paper presents a new method for solving a class of nonlinear optimal control problems with a quadratic performance index. In this method, first the original optimal control problem is transformed into a nonlinear two-point boundary…
Most causal inference methods consider counterfactual variables under interventions that set the treatment deterministically. With continuous or multi-valued treatments or exposures, such counterfactuals may be of little practical interest…
Hydrogen electrocatalysis (HER/HOR) exhibits an anomalous, non-Nernstian pH dependence that has motivated competing mechanistic narratives yet still lacks a unified, transferable, and quantitatively predictive description across conditions.…